Derek Bartlett

Derek Bartlett, Ph.D., is an Assistant Professor in the Division of Pharmacotherapy and Experimental Therapeutics at the UNC Eshelman School of Pharmacy. He holds a B.S. in Chemical Engineering from Stanford University and M.S./Ph.D. degrees in Chemical Engineering from Caltech, followed by postdoctoral training in cancer immunotherapeutics at the City of Hope. His research focuses on integrating PK-PD modeling with microfluidic systems to improve translational drug discovery, particularly in cancer therapeutics.

Education:

• B.S., Chemical Engineering, Stanford University
• M.S., Chemical Engineering, California Institute of Technology (Caltech)
• Ph.D., Chemical Engineering, Caltech
• Postdoctoral Training, Beckman Research Institute (City of Hope)

Research Interests:

Dr. Bartlett’s lab bridges pharmaceutical sciences, engineering, and medicine. Key areas include:

• Microfluidic platforms for PK-PD analysis
• Animal-alternative drug testing systems
• Functional precision medicine via in vitro/ex vivo drug testing
• Targeted drug delivery and molecular imaging

Publications:

Recent work emphasizes protein degradation mechanisms, microfluidic systems for dose optimization, and translational PK-PD modeling. These studies aim to enhance preclinical study reliability and precision medicine applications.

Labs/Teams:

The Bartlett Lab collaborates across disciplines to develop innovative drug discovery tools. Projects include:

• Combining computational modeling with experimental systems
• Designing microfluidic perfusion platforms for drug evaluation
• Exploring therapeutic strategies for cancer and immune-related conditions