معرفی
Delyth Graham is a Senior Research Scientist in the Institute of Cardiovascular and Metabolic Science (C&MS) at the British Heart Foundation Glasgow Cardiovascular Research Centre, University of Glasgow. Her research is focused on vascular diseases and comorbidities, with particular emphasis on hypertension, kidney disease, pregnancy complications, and stroke.
Dr. Graham's research interests span vascular structure and function, cellular signaling mechanisms, kidney disease biomarkers, cardiac remodeling, cognitive impairment, and dementia. Her work frequently examines the role of uromodulin in blood pressure regulation and salt-sensitive hypertension, as well as sex differences in preclinical models of hypertension and the cardiovascular effects of pregnancy complications like pre-eclampsia. She has made significant contributions to understanding vascular collagen type-IV in hypertension and cerebral small vessel disease.
Analysis of Dr. Graham's recent publications reveals a strong focus on molecular mechanisms underlying hypertension and vascular dysfunction, with particular attention to uromodulin biology, sex differences in cardiovascular disease, and the interplay between kidney function and blood pressure regulation. Her work often employs the stroke-prone spontaneously hypertensive rat model to investigate genetic and molecular pathways involved in cardiovascular disease.
Dr. Graham has been actively involved in mentoring and collaborative research, with numerous publications featuring junior researchers and students. Her work spans basic science investigations into molecular mechanisms through to translational research with potential clinical applications.
She is part of the research team at the British Heart Foundation Glasgow Cardiovascular Research Centre, working within the Institute of Cardiovascular and Metabolic Science. Her laboratory likely focuses on vascular physiology, molecular mechanisms of hypertension, and the role of kidney function in cardiovascular disease, utilizing both in vitro and animal model approaches.
