David Sept

David Sept, Ph.D., is a Professor in the Department of Biomedical Engineering at the University of Michigan, Ann Arbor. His research focuses on cytoskeletal dynamics, ion channel dysfunction, and drug delivery systems. He leads the Sept Lab, which investigates molecular mechanisms underlying cell migration, drug targeting for parasitic diseases, and nanoparticle pharmacokinetics. His work integrates computational modeling and experimental approaches to study actin and microtubule interactions, ion channel regulation in epilepsy, and multiscale biophysical systems.

Research interests include:

• Cytoskeleton dynamics and cell motility
• Design of drugs targeting sub-cellular filaments
• Ion channel regulation in disease
• Nanoparticle-based drug delivery systems
• Biomedical computation and modeling

Recent studies emphasize actin polymerization, microtubule tail interactions, and motor protein regulation. His lab develops innovative tools like the Phase Intensity Nanoscope (PINE) for live-cell imaging. No specific scientific awards are listed, though his work has been widely cited in the field of molecular dynamics simulations and drug design.