David J. Greenblatt

David J. Greenblatt is the Louis Lasagna, M.D. Professor at Tufts University School of Medicine with joint appointments in Psychiatry, Medicine, and Anesthesia. He serves as Special and Scientific Staff at Tufts Medical Center and holds an h-index of 121. His work focuses on clinical pharmacology and drug metabolism research.

Education:

• Doctor of Medicine, Harvard Medical School (1970)
• Bachelor of Arts, Amherst College (1966)

Research interests span molecular pharmacokinetics/pharmacodynamics, genetic/environmental factors in drug metabolism, drug-drug interactions, and determinants of drug response across demographics. Core methodologies include HPLC-mass spectroscopy, in vitro metabolism models, and pharmacokinetic modeling.

Publications demonstrate concentrated focus on obesity pharmacology, drug interactions, and personalized medicine strategies (2019-2025). Recent clinical studies examine altered drug disposition in special populations while methodological innovations include PBPK modeling and mass spectrometry techniques.

Awards and Honors:

• Oscar B. Hunter Career Award in Clinical Pharmacology (2022)
• Excellence in Clinical Pharmacology Award (2016)
• Man of Good Conscience Award (2016)
• Distinguished Faculty Award (2015)

Extensive grant history includes NIH-funded projects on drug metabolism, obesity pharmacology, and natural substance interactions. Leads translational pharmacology coursework at Tufts and maintains collaborations with key researchers at other institutions.

Directs laboratory operations focused on human drug metabolism using liver microsomal preparations and recombinant enzyme systems. Critical external collaborators include Lisa L. von Moltke, Hermann R. Ochs, Darrell R. Abernethy, and Michael H. Court.