Daniela E Matei

Daniela E Matei serves as Chief of Reproductive Science in Medicine and Diana, Princess of Wales Professor of Cancer Research at Northwestern University Feinberg School of Medicine. She holds dual professorships in Medicine (Hematology and Oncology) and Obstetrics and Gynecology (Gynecologic Oncology), with clinical practice at Northwestern Memorial Hospital.

Her academic foundation includes:

• MD from University of Medicine, Bucharest (1992)
• Internship and Residency at Stony Brook University Medical Center (1996)
• Fellowship at University of California, Los Angeles (2002)

Dr. Matei's research pioneers metabolic targeting in ovarian cancer, investigating ferroptosis induction through selenium deprivation and lipid oxidation manipulation. Her work bridges epigenetic regulation with immunotherapy enhancement, focusing on overcoming chemotherapy resistance through CRISPR-based metabolic vulnerability mapping and mRNA vaccine development.

Recent 2025 publications demonstrate clinical-translational integration across prehabilitation protocols, combination immunotherapies, and mechanistic cancer metabolism studies, establishing ovarian cancer as the central disease model for therapeutic innovation.

She leads active clinical trials including ACR-368-201 for platinum-resistant ovarian carcinoma and directs research within the Robert H. Lurie Comprehensive Cancer Center and Center for Reproductive Science.

National leadership roles span NRG Oncology committees, ASCO Taxonomy Committee, and Department of Defense Ovarian Cancer Academy, driving collaborative advances in gynecologic oncology standards.