معرفی
Dana Silverbush, PhD, serves as Assistant Professor of Cancer Biology at the University of Pennsylvania, focusing on computational approaches to decode cancer mechanisms in glioblastoma and leukemia through epigenetic and single-cell analyses.
Her academic foundation includes:
- BSc in Computer Science (magna cum laude), Tel-Aviv Academic College, Israel (2010)
- MSc in Computer Science (magna cum laude), Tel-Aviv University, Israel (2013)
- PhD in Computational Biology (magna cum laude), Tel-Aviv University, Israel (2018)
Dr. Silverbush specializes in computational oncology, integrating epigenetic dynamics, temporal signaling models, and single-cell genomics to study tumor evolution. Her work reveals how DNA methylation shifts drive glioblastoma recurrence and how neural circuits integrate with tumors, bridging computational biology with clinical neuro-oncology through advanced algorithmic frameworks.
Recent publications (2019-2024) demonstrate consistent leadership in high-impact cancer genomics, with emphases on epigenetic neural signatures in glioma, CAR T-cell therapy responses, and tumor microenvironment plasticity. Her collaborative studies in Nature, Cell, and Nature Genetics establish computational paradigms for modeling cancer progression across molecular, cellular, and circuit levels.
Her postdoctoral training at Mass General Hospital and The Broad Institute (2018-2023) and internships at Cambridge/MIT Microsoft Research groups cultivated expertise in temporal expression modeling and acute myeloid leukemia signaling.
