Constantina Pyrkotis

Dr Constantina Pyrkotis is a Lecturer in Pharmaceutical Chemistry at the Department of Health Sciences, University of Nicosia. She holds a PhD in Synthetic Organic Chemistry from Imperial College London (2008) and a BSc in Chemistry from Aristotle University of Thessaloniki (2004). Her research focuses on organic synthesis of bioactive compounds, fragment-based drug discovery, and development of antibiotics, anticancer agents, and UV-protective compounds.

Education:

• BSc in Chemistry, Aristotle University of Thessaloniki (2000-2004)
• PhD in Synthetic Organic Chemistry, Imperial College London (2004-2007)

Research interests include asymmetric synthesis, RNA-targeted antibiotics, and drug discovery strategies for tuberculosis and fungal infections. Her work contributes to UN Sustainable Development Goal 3 (Good Health and Well-being) through innovative pharmaceutical solutions.

Scientific achievements include:

• Development of novel RNA-binding molecules with nM potency against bacterial ribosomes
• Discovery of antifungal agents targeting pantetheine biosynthesis (Bill & Melinda Gates Foundation-funded)
• Design of UV-protective compounds with antioxidant activity
• Leadership in 18 research projects including cancer drug development and antibiotic resistance studies

Teaching responsibilities include organizing and instructing Pharmaceutical Chemistry courses (I-III) at the University of Nicosia, and serving as Deputy Chair of the Second Year Program in Pharmacy.