معرفی
Colin Rickman is an Associate Professor at Heriot-Watt University, affiliated with the School of Engineering & Physical Sciences, and holds roles in the Institute of Biological Chemistry, Biophysics and Bioengineering and the Institute of Chemical Sciences. His research focuses on molecular mechanisms of eukaryotic membrane secretion, particularly the spatial organization and regulation of SNARE proteins, using advanced optical techniques like super-resolution microscopy (PALM) and Förster resonance energy transfer (FRET).
- Affiliations: School of Engineering & Physical Sciences, Institute of Biological Chemistry, Biophysics and Bioengineering, Institute of Chemical Sciences
- Expertise: Molecular Biology, Biophysics, Membrane Fusion, Neuroendocrine Physiology
- Equipment Management: Edinburgh Super-Resolution Imaging Consortium (ESRIC), Tissue Culture Facility, Wet Lab Facility
Research interests include understanding how SNARE proteins mediate membrane fusion in specialized cellular regions, such as synaptic vesicle release sites. His work also explores SNARE accessory proteins (e.g., complexin, synaptotagmin) and their roles in regulating secretion. Advanced microscopy techniques are central to his investigations, including super-resolution imaging to map molecular arrangements at high resolution.
Publications span topics like metasurface-based filters for photonics, super-resolution microscopy methodology, and single-photon imaging technologies. His interdisciplinary approach bridges molecular biology, engineering, and biophysics.
He has contributed datasets and peer-reviewed manuscripts, including for the Journal of Neurochemistry. Collaborations involve experts in optics, biochemistry, and imaging technology.
