معرفی
Sudheer Kumar Cheppali is an Associate Research Scientist in the Department of Cellular & Molecular Physiology at Yale School of Medicine, Yale University. His research focuses on membrane biology, protein interactions, and cellular defense mechanisms against pathogens like SARS-CoV-2. Collaborations include work with Erdem Karatekin, Derek Toomre, and Craig B. Wilen.
Key research areas include:
- SNARE complex dynamics and membrane fusion mechanisms
- Role of synaptotagmin-1 in calcium-mediated vesicle docking
- Protein chaperone activities in seminal plasma proteins
- Biophysical studies using FRET and optical tweezers
- Antiviral defense mechanisms involving PLSCR1
Recent publications (2021-2025) highlight advancements in understanding:
- Membrane remodeling processes in migrasomes
- Molecular mechanisms of SNARE disassembly
- Drug delivery via lipid-based systems
- Heat-shock protein functions in thermal/oxidative stress
His work integrates biophysical techniques with cellular biology to explore fundamental membrane processes with implications for neurobiology, virology, and drug delivery.
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