Charles Wang

Charles Wang is a Professor in the Department of Basic Sciences at Loma Linda University School of Medicine, specializing in the Microbiology Division. He holds an MD, PhD, and MPH, reflecting a multidisciplinary expertise in medicine, toxicology, and public health. His research is centered on genomics and epigenetics, with a focus on molecular mechanisms underlying cancer, neurodevelopmental effects of environmental exposures, and microbiome interactions.

Dr. Wang’s research interests lie at the intersection of genomics, epigenetics, and molecular biology. He investigates how environmental factors such as e-cigarettes and chemical pollutants induce epigenetic changes that contribute to diseases like cancer and diabetes across generations. His work also explores the role of non-coding RNAs in chemoresistance, the genomics of cancer stem cells, and the impact of oxidative stress on oral pathogens. He employs advanced technologies including single-cell RNA sequencing, whole-genome sequencing, and DNA methylation profiling to uncover disease mechanisms and improve diagnostic and therapeutic strategies.

His recent publications reveal a strong trend in methodological innovation and biomedical application. He has contributed significantly to benchmarking studies for genomic technologies, including single-cell RNA-seq and cancer mutation detection, often publishing in high-impact journals. His work spans cancer biology, neurotoxicology, environmental health, and microbiology, demonstrating a broad and integrative research program.

Dr. Wang has not been mentioned with specific scientific awards in the provided text. However, his extensive publication record in top-tier journals and leadership in multi-center consortium studies (e.g., SEQC2) suggest significant recognition in his field.

He is actively involved in teaching and mentoring, as evidenced by his role in supervising dissertation research (IBGS 699) and directing multiple research courses (NSBB 697, PHRM 697, BCHM 697). His research is supported by collaborative grants and participation in large-scale genomic initiatives, although specific grant details are not listed. He works within a robust network of collaborators across various institutions, contributing to large consortia focused on genomic quality control and cancer genomics.

Dr. Wang leads a research program that integrates computational and experimental approaches to study gene regulation, epigenetic inheritance, and disease mechanisms. His laboratory likely focuses on generating and analyzing high-throughput genomic data to understand complex biological systems in cancer, neurology, and toxicology.