معرفی
Charles Parkos, MD, PhD is the Carl V. Weller Professor and Chair of the Department of Pathology at the University of Michigan Medical School. He trained at University of California at San Diego/Scripps Research Institute (MD/PhD, 1987), Brigham and Women’s Hospital (Pathology residency/fellowship), and Harvard Medical School before joining Emory University (1997–2014), where he served as Director of Experimental Pathology and full Professor.
Research Focus: Dr. Parkos investigates
- Mucosal inflammation mechanisms in inflammatory bowel disease (IBD)
- Neutrophil trafficking across intestinal epithelium
- Epithelial barrier dysfunction and repair
- Role of CD11b/CD18, CD47, SIRPα, and JAM family proteins
- Molecular regulation of leukocyte-epithelial interactions
- In vivo/ex vivo inflammation models
Scientific Contributions: His work has been instrumental in defining leukocyte migration dynamics across mucosal barriers, with over 189 publications in top journals (Nature, Cell, J Exp Med). He has held continuous NIH R01 funding since 1995 and served as President of the American Society for Investigative Pathology (2010–2011).
Mentorship & Leadership: Dr. Parkos has trained numerous graduate students and postdocs, many of whom hold prominent academic positions. He directed Emory’s Medical Scientist Training Program (2001–2014), expanding it to 88 students, and chairs grant review committees for the Crohn’s and Colitis Foundation of America.
