معرفی
Carsten Daub is an Associate Professor ("Docent" in the Swedish academic system) and Principal Researcher at Karolinska Institutet, where he leads the Clinical Transcriptomics research group within the Department of Medicine, Huddinge. His research focuses on understanding the molecular basis of gene regulation in diseases, particularly inflammation-related conditions such as asthma and obesity-related type 2 diabetes.
Dr. Daub's educational background includes a Master's degree in Chemistry from Technical University Berlin (2000) and a PhD in Bioinformatics from Max-Planck-Institute in Golm (2004). His career path includes a postdoc position at Karolinska Institutet (2004-2006), followed by work at RIKEN Yokohama where he became Team Leader at the Omics Science Center in 2007 and Facility Director of the Bioinformatics Core Facility in 2008. He returned to Karolinska Institutet in 2012 to establish his current research group and was appointed Principal Researcher in 2024.
His research program spans multiple interconnected areas:
- Genome-wide gene expression analysis using various RNA-Sequencing approaches
- Identification of transcription factors and regulatory elements responsible for disease-related expression differences
- Analysis of alternative promoters, anti-sense RNA, enhancers, and repeat elements
- Development of bioinformatics tools for high-throughput sequencing data analysis
- Spatial Transcriptomics applications for cancer classification and gene expression signature identification
Dr. Daub has published 56 peer-reviewed publications with an H-index of 30 and over 4000 citations. His recent work (2021-2025) shows strong emphasis on asthma research (nasal transcriptomic profiling and enhancer regulation), autism-associated environmental factors in neural development, zebrafish and canine genomics through consortium efforts (DANIO-CODE and DoGA), and metabolic disorders related to obesity and diabetes. His publications consistently integrate transcriptomic data with clinical phenotypes to elucidate disease mechanisms.
Dr. Daub actively supervises multiple PhD students and postdocs, and maintains close collaborations with clinical research groups at Karolinska Hospitals. He is involved in several major international research consortia including DANIO-CODE, DoGA, FANTOM5, and FANTOM6, contributing to genome annotation projects for zebrafish and canine models.
