معرفی
Thomas Perlmann is a Professor in Molecular Developmental Biology at the Karolinska Institutet, leading research at the Department of Cell and Molecular Biology and serving as Director of the Stockholm Branch of the Ludwig Institute for Cancer Research. He also holds the position of Secretary General of the Nobel Assembly and Nobel Committee for Physiology or Medicine since 2016.
- Ph.D., Karolinska Institutet, 1991
- M.Sc., Stockholm University, 1987
Research Interests: The Perlmann lab investigates the specification and maintenance of dopamine neurons in the central nervous system, with a focus on transcriptional regulation, signaling pathways, and regenerative medicine applications for Parkinson’s disease and other neurodegenerative disorders. His work bridges developmental biology and neuroscience, emphasizing the role of transcription factors in neuronal identity and function.
Recent Research Trends: Perlmann’s recent publications highlight the use of single-cell RNA sequencing to dissect dopamine neuron heterogeneity, epigenetic regulation during development, and transcriptomic changes in Parkinson’s disease models. His studies increasingly leverage multiomics and bioinformatics to map neuronal lineage trajectories and gene expression dynamics.
- Scientific Awards:
- Royal Medal by HM the King (2025)
- Nicholson Lecturer, Rockefeller University (2011)
- Göran Gustafsson Prize in Molecular Biology (1999)
- Eric K. Fernström Young Investigator Prize (1997)
Advising & Collaborations: While no student names are explicitly listed, Perlmann collaborates extensively with researchers such as Malin Parmar, Agnete Kirkeby, and Per Svenningsson on projects related to neuronal development and cell therapy. His lab receives funding from institutions like the Ludwig Institute for Cancer Research.
Labs & Teams: The Perlmann Lab at Karolinska Institutet includes researchers like Linda Gillberg, Laura Lahti, and Behzad Yaghmaeian Salmani, who work on mouse models, single-cell transcriptomics, and bioinformatics to study dopamine neuron biology.
