معرفی
Konstantinos Meletis is a Professor at the Department of Neuroscience, Karolinska Institutet, Stockholm. His research focuses on understanding the neural circuit mechanisms underlying motivated behaviors and the circuit imbalances associated with mood disorders. He leads a research group investigating how brain circuits regulate emotional states, stress responses, and decision-making processes.
Education & Appointments:
- PhD in Cell and Molecular Biology, Karolinska Institutet (2006)
- Docent in Systems Neuroscience, Karolinska Institutet (2015)
- Professor of Systems Neuroscience, Karolinska Institutet (2021–present)
Research Interests:
Dr. Meletis' work combines cutting-edge techniques such as optogenetics, spatial transcriptomics, and circuit mapping to study dopamine systems, striatal pathways, and the molecular basis of mood disorders. Key themes include:
- Circuit mechanisms of chronic stress and aversive states
- Neural substrates of prosocial motivation
- Mapping brain-wide neuronal connectivity
- Role of hypothalamic-habenula circuits in emotional regulation
Grants & Awards:
- 2024 Arvid Carlsson Foundation Prize for neuropsychiatric research
- Swedish Research Council grants (multiple awards since 2013)
- Knut and Alice Wallenberg Foundation grant (2020–2025)
Lab & Collaborations:
His group collaborates with teams across neurobiology and computational neuroscience. Key projects include developing molecular atlases of brain regions and studying neuronal vulnerability in Parkinson’s disease. The lab uses advanced imaging and genetic tools to dissect circuit-level dysfunction in mental health disorders.
