معرفی
Carlos J. Camacho, PhD, is an Associate Professor in the Department of Computational and Systems Biology at the University of Pittsburgh. His research focuses on modeling molecular recognition mechanisms and developing computational tools for structural prediction and drug discovery. Key areas include protein-protein interactions, protein-DNA interactions, and drug development targeting protein-protein interfaces. He leads the Camacho Lab, which has pioneered technologies such as ClusPro and PepDock-PDZ for predicting biomolecular complexes.
Dr. Camacho holds a PhD in Physics from the University of Maryland, College Park. His work integrates thermodynamics and molecular dynamics to address fundamental questions in structural biology, with applications to cancer therapy, neurodegenerative diseases, and viral pathogenesis. Notable projects include the design of small-molecule inhibitors for Kv2.1/syntaxin interactions and the development of nanobody-based drug delivery systems.
His lab has contributed to open-source software tools like AnchorQuery and ZINCPharmer, enabling efficient virtual screening of chemical libraries. Collaborative efforts span disciplines from computational biophysics to clinical translation, reflecting his commitment to bridging basic science and healthcare innovation.
- Education: PhD in Physics, University of Maryland, College Park
- Labs/Teams: Camacho Lab, Center for Simulation and Modeling at the University of Pittsburgh
- Key Tools: ClusPro, PepDock-PDZ, Anchor Database
