Bruno Fève

Bruno Fève is a Professor at Sorbonne University, affiliated with the Pierre and Marie Curie Faculty of Medicine. He serves as team leader for the Lipodystrophies, Metabolic and Hormonal Adaptations, and Aging research group at Saint-Antoine Site, Paris. His work integrates clinical and fundamental research through collaborations with CRSA, IHU ICAN, and European networks ECLip/Endo-ERN.

• Research Pillars: Genetic/acquired lipodystrophies, HIV-related metabolic alterations, glucocorticoid-induced insulin resistance, reproductive metabolism interactions
• Methodologies: Translational approaches combining clinical cohorts, transgenic mouse models, and cellular systems
• Clinical Impact: Development of diagnostic tools, therapeutic education programs, and metabolic risk stratification

Publication Trends reveal expertise in adipose tissue pathophysiology, nuclear receptor modulation (RORα, glucocorticoid receptor), and metabolic complications of HIV/antiretroviral therapies. Key contributions appear in Cell, Diabetes, and Journal of Clinical Endocrinology & Metabolism.

Collaborations span genetics (LMNA/AGPAT2/PLIN1), cardiovascular research (AOC3/RIPK3), and reproductive endocrinology (anti-Müllerian hormone studies). His work addresses both rare monogenic diseases and common metabolic disorders through multidisciplinary frameworks.