Bruce F. Smith

Dr. Bruce F. Smith is a Professor at Auburn University's College of Veterinary Medicine, Director of the Auburn University Research Initiative in Cancer (AURIC), and Scientist at the Scott-Ritchey Research Center. He holds a VMD (1988) and PhD in Molecular Biology and Genetics (1993) from the University of Pennsylvania.

• University of Pennsylvania, VMD (1988)
• University of Pennsylvania, PhD in Molecular Biology and Genetics (1993)

Dr. Smith's research bridges genetic therapy for inherited muscular dystrophies and cancer treatment through oncolytic virus development. His work focuses on canine models of Duchenne Muscular Dystrophy (DMD) and personalized viral vectors for tumors using synthetic biology. Current projects analyze cardiac defects in DMD and employ RNA sequencing for cancer gene expression profiling.

His 15 most recent publications emphasize synthetic virology for VSV engineering, oncolytic virus design with immune checkpoint modulation, osteosarcoma combination therapies, and multi-omics tumor characterization. Key disciplines include virology, gene therapy, and comparative oncology.

Scientific awards include the Kleberg Fellowship in Medical Genetics. Collaborations span Auburn University, Washington University St. Louis, and University of Alabama Birmingham. Research involves canine adenovirus, CRISPR/Cas9 applications, and tumor microenvironment analysis.