Brian Michael Luna

Brian Michael Luna is an Assistant Professor at the University of Southern California's Department of Molecular Microbiology and Immunology. His research focuses on combating antibiotic tolerance mechanisms in bacterial pathogens, particularly ESKAPE organisms. Utilizing synthetic biology, microbial genetics, and preclinical mouse models, he investigates resistance and persister cell formation to guide next-generation therapeutics.

Key research areas include antibiotic resistance dynamics, immunomodulatory therapies, and pharmacokinetic/pharmacodynamic modeling. His work spans molecular microbiology, infectious disease pathogenesis, and antimicrobial development.

Recent publications highlight advancements in polymyxin efficacy testing under physiological conditions, humanized antibiotic dosing strategies, and monoclonal antibody therapies for Acinetobacter baumannii. He employs cutting-edge pharmacokinetic modeling and infection models to optimize treatment regimens.

Dr. Luna's email is brianlun@usc.edu, and his research contributes to reducing healthcare costs associated with antibiotic-resistant infections.