معرفی
Brian D. Keith is an Adjunct Professor in the Department of Cancer Biology at the University of Pennsylvania and a member of the Abramson Family Cancer Research Institute. He is affiliated with the Cell and Molecular Biology Graduate Group and collaborates with leading researchers like Dr. Celeste Simon and Dr. Carl June.
- Education:
- Sc.B. in Biology, Brown University, 1980
- Ph.D. in Plant Molecular Biology, The Rockefeller University, 1987
Research Interests focus on cellular adaptation to hypoxia, particularly through hypoxia-inducible factors (HIFs), with applications in cancer progression, metabolic stress, and tumor microenvironmental dynamics. His work includes mouse genetic models and CAR-T cell therapy adaptation for solid tumors.
Awards and Collaborations include high-impact publications in journals like Nature, PNAS, and Genes & Development. His research intersects metabolism, transcriptional regulation, and microenvironmental stress in cancer and development.
Lab Affiliation: Works closely with Dr. Celeste Simon's lab, contributing to studies on hypoxia-induced metabolic shifts and lipid homeostasis in tumors.
