معرفی
Bo Liu is a Professor in the Department of Surgery at the University of Wisconsin–Madison School of Medicine and Public Health. With a focus on vascular pathology, his research explores molecular mechanisms of vascular inflammation, necroptosis in occlusive diseases, and biomedical material development. He directs active NIH-funded projects on RIPK3 in aneurysms and thrombosis, while advancing gene delivery systems and 3D-printed vascular grafts.
- Education: MS (1986, Beijing University), PhD (1993, SUNY Downstate)
- Mentorship: Trained 12 postdocs and graduate students including Jason Ren, Ting Zhou, and Vijayah Pilli
Research interests span vascular inflammation, regulated cell death, and extracellular matrix biology, with translational applications in abdominal aortic aneurysm and venous thrombosis. His lab pioneered necroptosis inhibitors and characterized TSP1 as a key inflammatory mediator.
Recent publications highlight single-cell RNA sequencing of disease heterogeneity, RIPK3 phosphorylation during cell division, and EV-mediated signaling in thrombosis. Collaborations span biochemistry, materials science, and clinical disciplines.
- Scientific Awards:
- NIH R01HL149404 (PI, 2020-2024)
- NIH R01 HL158073 (PI, 2021-2025)
- AHA Transformation Award 20TPA35490307 (2021-2023)
- University of Wisconsin Research Forward Grant (2022-2024)
His lab integrates CRISPR gene editing, proteomics, and nanotechnology, maintaining a multidisciplinary environment with engineers and clinicians. Current projects include developing self-powered stents and characterizing pathogenic signaling networks in vascular diseases.
