Bill B. Messer

William B. Messer is an Assistant Professor in the Department of Medicine at Oregon Health & Sciences University (OHSU), with a focus on virology and immunology. Previously, he was a Clinical Assistant Professor at the University of North Carolina (UNC) School of Medicine. His research emphasizes dengue virus genetics, alphavirus pathogenesis, and immune responses to SARS-CoV-2. He holds an M.D. and Ph.D. from UNC, where his doctoral work investigated dengue virus evolution in Sri Lanka.

Education:

• Ph.D., Ecology, University of North Carolina at Chapel Hill, 2003
• M.D., University of North Carolina School of Medicine, 2006
• Residency in Internal Medicine, UNC Hospitals, 2009
• Fellowship in Infectious Diseases, UNC School of Medicine, 2012

Research Interests:

Dr. Messer studies viral evolution, immune responses to flaviviruses (e.g., dengue, Zika), and vaccine development. His work includes multi-omic profiling of immune dysregulation in viral infections and antibody dynamics in SARS-CoV-2. His lab explores viral genetics and host-pathogen interactions, with implications for public health and clinical interventions.

Publications:

His work spans high-impact journals, focusing on viral pathogenesis, vaccine efficacy, and immune correlates of disease severity. Recent studies include analyses of SARS-CoV-2 antibody responses and cross-neutralizing immunity against alphaviruses.

Labs/Teams:

Collaborates with OHSU and international teams on viral research, including projects on dengue epidemiology and SARS-CoV-2 diagnostics.