Bernice E. Morrow

Bernice E. Morrow, Ph.D., is a Professor holding positions in three departments at Albert Einstein College of Medicine: Genetics, Obstetrics & Gynecology and Women's Health, and Pediatrics (Pediatric Cardiology). She holds the Sidney L. and Miriam K. Olson Chair in Cardiology and serves as Director of the Division of Translational Genetics and Faculty Advisor for the Genomics Core. Her research focuses on understanding the genetic and epigenetic mechanisms underlying birth defects, particularly in 22q11.2 deletion syndrome (22q11.2DS). Using single-cell omics and functional genomic approaches, her lab investigates congenital heart defects, neural crest cell signaling, and inner ear development.

Her research integrates human genetic studies with mouse models to identify modifiers of disease severity in 22q11.2DS. Key genes under study include TBX1, DGCR8, and CRKL, which are linked to heart and neural defects. Collaborations with the Montefiore-Einstein Regional Center for 22q11.2DS enable international recruitment of patients for genomic analyses.

Recent work emphasizes chromatin regulation, epigenetic pathways, and single-cell transcriptomics to dissect disease mechanisms. Articles highlight discoveries in Tbx1-dependent developmental pathways and genetic modifiers of heart defects. While no scientific awards are explicitly listed, her contributions to understanding congenital disorders are recognized through her academic leadership roles. Advising and grant details are not provided in the text, but her roles in core facilities and division leadership reflect active involvement in translational research.

Labs and teams include the Division of Translational Genetics and Genomics Core, where she oversees functional genomic studies. Her work bridges basic science with clinical insights into congenital anomalies, aiming to improve diagnostic and therapeutic strategies for patients with genetic syndromes.