B J R Whittle

B J R Whittle is a Professor at the William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London. His research focuses on inflammation, immunology, and pharmacology, particularly in the context of inflammatory bowel disease, prostaglandins, and leukotriene biology. He has led studies on the attenuation of colitis using novel inhibitors of leukotriene A4 hydrolase and has contributed to understanding mechanisms of gastrointestinal inflammation and drug development.

Whittle's work includes investigations into pulmonary hypertension, prostacyclin receptor agonists, and the role of nitric oxide in mucosal injury. His affiliations include collaborations with Johnson & Johnson Pharmaceutical Research & Development, LLC, and he has published extensively on topics ranging from cytokine regulation to vascular biology. His research has implications for therapeutic strategies in gastrointestinal and respiratory diseases.