معرفی
Anja Sandström is a Professor at the Department of Medicinal Chemistry; Drug Design and Discovery, Uppsala University, with a focus on peptides and peptidomimetics in drug discovery for infectious diseases. She serves as Deputy Dean of Education at the Faculty of Pharmacy and has held leadership roles including Study Director and Assistant Head of Department.
Her research spans
- Antiviral protease inhibitors (SARS-CoV-2, hepatitis C, Zika, tick-borne encephalitis)
- Antibacterial agents targeting LpxH and signal peptidase
- Peptidomimetic analgesics for neuropathic pain
- Chemical methodologies in solid-phase peptide synthesis
- Structure-activity relationships in drug design
- Computational and experimental screening techniques
Recent publication trends highlight her work on
- Broad-spectrum antivirals against coronaviruses and flaviviruses
- Novel scaffolds for protease inhibition
- Metabolic stability and permeability of peptide-based drugs
- Advanced synthetic methods via palladium catalysis
- Modulation of substance P fragments for pain relief
- Targeting bacterial enzymes for antibiotic development
Scientific accolades include multiple teaching awards from Uppsala University and the Pharmaceutical Student Union, with recognition as an excellent teacher in 2017. She has contributed to 15+ peer-reviewed articles in journals like Antimicrobial Agents and Chemotherapy, Journal of the American Chemical Society, and European Journal of Medicinal Chemistry, covering antivirals, antibiotics, and neuropharmacological agents.
Her laboratory collaborates on multidisciplinary projects integrating
- Organic synthesis
- Biochemical assays
- Computational modeling
- Pharmacokinetic studies
- Structure-based drug design
- Translational research in pain and infectious diseases
