معرفی
Anders Karlén is a Professor at the Department of Medicinal Chemistry; Drug Design and Discovery at Uppsala University. He specializes in computational medicinal chemistry, focusing on hit identification, lead development, and drug discovery targeting infectious diseases like Tuberculosis and Gram-negative infections. His current role includes leading five anti-bacterial drug discovery projects.
Research Focus
His research integrates computational methods with synthetic chemistry to develop novel antibiotics. Key areas include signal peptidase inhibition, lipopolysaccharide synthesis targeting, and macrocyclic drug design.Recent Publications
Publications emphasize antibiotic development partnerships (Nature Reviews Drug Discovery, 2025), novel antibiotic classes (PNAS, 2024), and p53-targeted cancer therapies (Frontiers in Molecular Biosciences, 2022). Work spans enzymology, synthetic chemistry, and computational modeling.Awards & Grants
No specific awards listed, but his leadership in EU initiatives like ENABLE and AMR Accelerator highlights collaborative grant efforts.Labs & Teams
Leads a multidisciplinary team in drug discovery, collaborating across academia and industry to tackle antibiotic resistance.۰مقاله منتشرشده
