Scott Lovell

Dr. Scott Lovell is a Senior Lecturer in Chemical Biology at the University of Bath's Department of Life Sciences. He leads the Lovell Group researching covalent drug discovery at the chemistry-biology-medicine interface, focusing on cancer and antibiotic-resistant infections. His team specializes in peptide synthesis, chemical proteomics, and phage display technologies.

Dr. Lovell's research interests include:

• Covalent phage display for undruggable proteins
• Targeted covalent macrocycles (TCMs)
• Protease-activated imaging agents
• Covalent fragment libraries for cancer treatment

His recent publications demonstrate a focus on developing covalent inhibitors through innovative screening platforms, with applications spanning transcription factor inhibition, antimicrobial strategies, and peptide-based drug discovery. Research strongly emphasizes translational approaches combining synthetic chemistry with molecular biology.

Dr. Lovell is currently PI on multiple funded projects including:

• Tackling the Undruggable Cancer Proteome with Covalent Macrocycles (EPSRC)
• Synthesis of Targeted Covalent Macrocycle Libraries (Royal Society)
• A Phage Display Approach for Undruggable Proteins (Academy of Medical Sciences)

He welcomes doctoral students to his interdisciplinary research team investigating novel chemical modalities for disease treatment.