Anita Huttner

Anita Huttner, MD is an Associate Professor of Pathology at Yale School of Medicine with extensive affiliations across Yale's research ecosystem. She holds primary appointments in the Department of Pathology and participates in numerous specialized research centers including the Alzheimer's Disease Research Center (ADRC), Brain Tumor Center, Genomics, Genetics, and Epigenetics Program, and Yale Cancer Center. Her dual expertise spans neuropathology and molecular diagnostic pathology, creating a unique interdisciplinary approach to understanding brain diseases.

Dr. Huttner's research focuses on neurological disorders with particular emphasis on Alzheimer's disease, brain tumors, and epilepsy. She employs innovative techniques including subcellular proteomics, induced pluripotent stem cell (iPSC) modeling, and advanced imaging analysis to investigate disease mechanisms. Her work bridges traditional microscopic examination with modern genomic analysis, allowing her to incorporate genetic sequencing results into visual tumor analysis. Recent publications demonstrate her leadership in identifying biomarkers for neurological conditions and developing novel diagnostic approaches for brain disorders.

Analysis of Dr. Huttner's recent publications (2023-2025) reveals a strong focus on Alzheimer's disease mechanisms, brain tumor classification using advanced imaging techniques, and neurological conditions like Tourette Disorder and epilepsy. Her work frequently employs cutting-edge methodologies including single-cell transcriptomics, subcellular proteomics, and AI-based analysis of medical imaging. These publications appear in high-impact journals such as Nature Neuroscience, Nature Aging, and Biological Psychiatry, demonstrating the significance of her contributions to the field.

• Averill A. Liebow Award for Excellence in the Teaching of Pathology Residents (2009)
• Nomination for the Alice Bohmfalk Teaching Award in Basic Science (2005)

Dr. Huttner maintains an active research program with numerous collaborations across Yale and beyond. Her work involves both basic science investigations and clinical applications, with a particular focus on translating laboratory findings into improved diagnostic approaches and potential treatments. She serves as a Sub Investigator for the SV2A PET Imaging clinical trial focused on epilepsy patients, demonstrating her commitment to translational research that directly impacts patient care. Her mentorship extends to pathology residents, with recognition for excellence in teaching.

Based at the Brady Memorial Laboratory at Yale, Dr. Huttner's work integrates multiple research approaches to understand brain pathology at both cellular and molecular levels. Her laboratory investigations focus on recreating brain disorders using stem cell technology to model conditions like epilepsy and Alzheimer's disease, with the ultimate goal of developing better treatments for neurological conditions and brain tumors.