Andre M. Oliveira

Dr. Andre M. Oliveira is a distinguished Medical Geneticist and Pathologist at Mayo Clinic in Rochester, Minnesota. He holds dual appointments in the Department of Laboratory Medicine and Pathology with a focus on Anatomic Pathology. Dr. Oliveira is a leading expert in molecular pathology of sarcomas and bone tumors, with particular expertise in gene fusions and oncogenes like USP6.

His educational background includes:

• PhD in Pathology from Escola Paulista de Medicina, Universidade de São Paulo (2010)
• Postgraduate Fellowship in Cytogenetics from Mayo Medical School (2005)
• Residency in Molecular Genetic Pathology from Mayo School of Graduate Medical Education (2004)
• Postgraduate Fellowship in Clinical Molecular Genetics from Brigham and Women's Hospital and Harvard (2004)
• MD from Federal University of Rio de Janeiro (1995)

Dr. Oliveira's research primarily focuses on the molecular mechanisms of sarcomas and bone tumors, with special emphasis on USP6 oncogene and its role in tumor development. His work has significantly advanced understanding of gene fusions in sarcomas, particularly in aneurysmal bone cysts and nodular fasciitis. He has pioneered research showing how USP6 functions both as an oncogene and tumor suppressor depending on context, with implications for immunotherapy approaches in Ewing sarcoma.

His recent publications demonstrate a strong focus on molecular diagnostics for sarcomas, with particular attention to developing clinical next-generation sequencing assays for detecting gene fusions. His work spans from basic molecular mechanisms to clinical applications, with an increasing emphasis on how molecular findings can inform treatment approaches, particularly in the realm of immunotherapy.

Dr. Oliveira has received several prestigious awards throughout his career:

• Hobart K.B. Allenbach Award for Outstanding Resident in Pathology (2001)
• Pediatrics Award from Universidade Federal do Rio de Janeiro (1995)
• Doctor of Medicine cum laude from Universidade Federal do Rio de Janeiro (1995)
• Internal Medicine Award from State Secretary of Health of Rio de Janeiro (1995)
• Internal Medicine Award from Brazilian Navy Army (1995)

As a senior researcher at Mayo Clinic, Dr. Oliveira has mentored numerous trainees and junior faculty in molecular pathology. His laboratory has been consistently funded through NIH and foundation grants supporting research on sarcoma genetics and molecular diagnostics. He serves as a principal investigator on multiple studies focused on developing molecular diagnostic tools for sarcomas and understanding the pathogenesis of rare bone and soft tissue tumors.

Dr. Oliveira leads a research team within the Department of Laboratory Medicine and Pathology that specializes in molecular analysis of sarcomas. His laboratory utilizes advanced genomic techniques including next-generation sequencing to identify novel gene fusions and molecular markers that can improve diagnosis and treatment of sarcomas. The team collaborates extensively with surgical pathologists, orthopedic oncologists, and medical oncologists to translate molecular findings into clinical practice.