معرفی
Alexandra Badea is an Associate Professor in Radiology and Neurology, and an Assistant Professor of Biomedical Engineering at Duke University. She holds a joint appointment at the Center for Brain Imaging and Analysis (BIAC) and is a core faculty member at the Center for in Vivo Microscopy. Her research focuses on neuroimaging techniques for characterizing neurological conditions like Alzheimer’s disease, leveraging MRI and diffusion tensor imaging (DTI) to study brain microstructure and connectivity.
Dr. Badea’s work integrates imaging with genetics and behavioral data to develop multivariate biomarkers for early disease detection. She uses high-performance computing for advanced image analysis, including compressed sensing and deformable registration. Key projects include studying genetic risk factors (APOE alleles) and the impact of exercise on brain networks in mouse models. She has led Bass Connections teams involving undergraduate students in translational research, offering courses like BME 394/493 and NEUROSCI 493.
Her grants include funding from NIH and NIA for studies on Alzheimer’s-cardiac interactions, aging mouse models, and immune-regulated metabolism. She has published extensively in journals like Neuroimage, PLoS One, and Brain Structure & Function. Dr. Badea also mentors graduate students and postdocs, emphasizing interdisciplinary approaches to neuroimaging and promoting STEM inclusion for women.
Her lab develops tools like the SAMBA pipeline for small-animal brain analysis and collaborates on open-source software. She maintains active roles in Duke’s medical school and radiology departments, contributing to both clinical and preclinical imaging research.
