معرفی
Megan Madonna is an Assistant Research Professor in the Department of Biomedical Engineering at Duke University, where she earned her Ph.D. in 2020. She teaches multiple Bass Connections research teams (ISS 796T/795T/396T/395T) focused on Information, Society & Culture, alongside engineering project courses including BME 493/494, BME 462L, BME 791, and EGR 393.
Her research centers on optical metabolic imaging to investigate cancer metabolism, particularly in breast cancer subtypes. She develops advanced multi-probe and multi-scale imaging platforms capable of simultaneously quantifying metabolic and vascular endpoints such as fatty acid uptake, mitochondrial activity, and oxygen saturation in vivo. Her work specifically targets chemoresistance mechanisms in triple-negative and Her2+ breast cancer, identifying metabolic vulnerabilities during residual disease and recurrence.
Analysis of her 15 most recent publications reveals a consistent focus on translating optical imaging techniques into clinical applications for cancer therapy guidance. Her work demonstrates strong interdisciplinary collaboration, particularly with Dr. Nimmi Ramanujam's lab, and spans from fundamental metabolic imaging development to clinical implications for chemotherapy monitoring.
Dr. Madonna actively mentors students through graduate independent study (BME 791) and capstone projects (BME 493/494), while leading interdisciplinary Bass Connections teams that integrate engineering with societal considerations. She contributes to Duke's Global Women's Health Technologies ecosystem through her editorial work on gender-specific biomedical research.
