معرفی
Alexander Bartelt serves as Professor of Cardiovascular Metabolism and DZHK Junior Research Group leader at the Institute for Cardiovascular Prevention, Ludwig Maximilian University of Munich. His work investigates molecular mechanisms of cellular stress in metabolic diseases including obesity, diabetes, and atherosclerosis, with emphasis on metabolic adaptation and homeostasis disruption through nutrient excess and cellular waste accumulation.
His research targets brown adipose tissue thermogenesis, endoplasmic reticulum/mitochondrial stress responses, and inflammatory pathway activation in metabolic disease clusters. The lab employs cell models, transgenic mice, and clinical collaborations to translate basic findings into human relevance, focusing on adipocyte health, energy balance regulation, and obesity-associated comorbidities.
Analysis of recent publications reveals consistent focus on brown adipose tissue's protective roles in lipid metabolism, cholesterol homeostasis, and cardiovascular protection. His work demonstrates mechanistic links between thermogenic adipocytes, reverse cholesterol transport, and atherosclerosis prevention, with growing emphasis on oxidative stress responses and protein recycling pathways as evidenced by 2024 publications.
Major recognitions include:
- Karl Lohmann Award of the GBM
- European Atherosclerosis Society Young Investigator Award
- Norman Salem Jr. Early Career Award of ISSFAL
- Friedmund Neumann Award of the Ernst Schering Foundation
- ERC Starting Grant 2019 for muscle cell metabolism research
The Bartelt Lab operates within Munich's Institute for Cardiovascular Prevention with core funding from the DZHK and ERC. Current projects explore muscle-adipose tissue crosstalk in metabolic homeostasis using advanced models including transgenic mice and clinical partnerships, with recent 2024 discoveries in mitochondrial thermogenesis control and oxidative stress protection mechanisms.
