Albrecht von Arnim

Albrecht von Arnim serves as Professor in the Department of Biochemistry, Cellular and Molecular Biology at the University of Tennessee, Knoxville, where his laboratory investigates translational regulation mechanisms in plants. His research integrates molecular genetics, biochemistry, and computational approaches to study how environmental cues and developmental processes control protein synthesis.

Education

• Ph.D. from University of East Anglia (UK)

Research Focus

Professor von Arnim's work centers on mRNA translation regulation in Arabidopsis thaliana, examining how plants adapt to environmental stresses through translational control. His lab employs genome-wide translatome assays, genetic mutant analysis, and mathematical modeling to investigate ribosome function, upstream open reading frames, and circadian clock interactions. Key discoveries include chloroplast-mediated activation of the GCN2 kinase during stress and light-dependent integration of circadian signals with translational efficiency.

Publication Trends

His 2015-2020 publications reveal consistent investigation of environmental signal transduction (light, cold, salt stress) converging on translational regulation. A dominant theme involves reactive oxygen species from chloroplasts activating GCN2 kinase, while circadian clock interactions with ribosomal proteins like RPS6 emerge as recurring mechanistic foci across multiple studies.

Laboratory Operations

• Primary lab location: Hesler Hall 230
• Collaborative partnerships with Oak Ridge National Laboratory computational biologists
• Multi-pronged methodology combining genetic analysis, reporter assays, and bioinformatics