معرفی
David Gatfield is an Associate Professor at the Center for Integrative Genomics (CIG), University of Lausanne. He holds a PhD from the University of Tübingen and completed postdoctoral training at EMBL Heidelberg and the University of Geneva, focusing on mRNA transport and circadian clocks. His research integrates circadian biology and RNA regulation, exploring post-transcriptional mechanisms in rhythmic gene expression. Key areas include translational control via ribosomes, uORFs, and circadian links to metabolism.
Education:
- PhD in Biochemistry, University of Tübingen
- Postdoc at EMBL Heidelberg (mRNA transport/degradation)
- Postdoc at University of Geneva (circadian clocks/RNA biology)
Research Interests:
- Circadian clock regulation of translational processes
- uORF-dependent gene expression control
- Ribosomal collisions and translational pausing
- Connections between circadian rhythms and metabolic health
Recent Work Trends:
- Exploring ribosome dynamics in obesity and aging
- Linking NMD pathways to circadian clock function
- Investigating SARS-CoV-2 translation mechanisms
- RNA decay pathways' role in metabolic regulation
Funding & Grants:
- Swiss National Science Foundation
- Fondation Leenaards
- Novartis Foundation for Biomedical Research
Labs/Teams: Leads CIG research group focusing on translational control and circadian clocks, collaborating across multiple institutions including ETH Zurich and University Hospital Lausanne.
