Charlotte von Gall

Charlotte von Gall is a Professor at the Institute of Anatomy II, Heinrich-Heine-University. Her research focuses on the cellular and molecular mechanisms of synchronization within the mammalian circadian system, particularly studying the suprachiasmatic nucleus (SCN) as the endogenous rhythm generator.

• Investigates SCN integration of light signals and peripheral oscillator coordination
• Uses conditional knockout mice to study clock gene roles in feeding regulation, glia-neuron interactions, neurogenesis, and synaptic function
• Links circadian dysfunction to accelerated aging, metabolic disruption, and cognitive deficits

Her publications highlight circadian rhythm analysis across neurobiology, endocrinology, and developmental biology domains. Key trends include:

• Mechanisms of SCN synchronization in aging and genetic models
• Melatonin signaling pathways in the pars tuberalis
• CREB-mediated integration of photic and neurochemical stimuli
• Role of ubiquitin pathway defects in neurodegenerative circadian disruption
• Ontogenetic development of circadian clock proteins
• Photoperiodic memory and clock resetting protocols

The research emphasizes cross-disciplinary approaches to circadian system dysfunction in metabolic, neurological, and age-related contexts.