Albert S Edge

Albert S. Edge is the Eaton-Peabody Professor of Otolaryngology Head and Neck Surgery at Harvard Medical School, with primary affiliation at the Massachusetts Eye and Ear Infirmary (MEEI) in Boston, MA.

His research focuses on auditory neuroscience and regenerative medicine, particularly exploring molecular mechanisms of hair cell regeneration and auditory neuron differentiation. Key areas include

• Wnt/Notch signaling pathways
• Lgr5 stem cell activation
• Epigenetic regulation of gene expression
• CRISPR/siRNA-based gene editing

Recent publications highlight

• cochlear organoid development
• transcriptional programs in cell fate
• pharmacological approaches to hearing recovery
• cross-species regeneration comparisons

His lab at the Eaton-Peabody Laboratory investigates epithelial cell dynamics in the inner ear, aiming to rebuild damaged sensory circuits through stem cell therapies and molecular interventions.