معرفی
Alain HEDOUX is a Professor at the University of Lille within the Materials and Transformations Unit (UMET, CNRS UMR 8207), specifically in the Molecular and Therapeutic Materials research team. His office is located at Building P5, room 253, in the Scientific City campus, Villeneuve d'Ascq, France. He actively contributes to pharmaceutical materials research and doctoral supervision at the university.
His educational background includes:
- Physics studies at IUT A (Measurements department) covering mechanics of point particles, rigid solids, and deformable solids (elasticity)
- Master's degree in Structural organization of condensed states of matter
Professor HEDOUX specializes in analyzing structural organization and dynamics of glass-forming molecular materials in amorphous/crystalline states, phase transformation mechanisms, and stabilization of therapeutic materials (small molecules, proteins) using excipients. His work leverages Raman spectroscopy, neutron scattering, X-ray diffraction, and calorimetry to address pharmaceutical stability and bioavailability challenges.
His recent publications (2021-2025) demonstrate consistent application of low-frequency Raman spectroscopy to investigate polyamorphism in drugs like linezolid, co-amorphous/deep eutectic solvent formulations, and molecular confinement in mesoporous silica carriers. Key trends include metastable state exploration, drug loading optimization, and excipient-driven stabilization mechanisms for hydrophobic therapeutics.
No scientific awards are documented in the provided text.
He has co-directed seven PhD students: Basma MOUTAMENNI (2024) on mesoporous silica drug loading, Benjamin MALFAIT (2019) on drug bioavailability, Tatiana STARCIUC (2017) on biomolecular stabilization, Sarah Nasser (2017) on caseinate powders, Samira Achir (2014) on protein stabilization, Adrien Lerbret (2005) on sugar bioprotection, and Thomas Denicourt (2002) on subcooled systems. Graduates now work at Astrazeneca, Ingredia Dairy Experts, and academic institutions. While UMET participates in ANR/ERC/Interreg projects, specific grants under his leadership are not detailed.
As part of the Molecular and Therapeutic Materials team, he utilizes UMET's experimental platforms including the PMEL electron microscopy facility and FireResist platform for advanced materials characterization.
