معرفی
Adrián Cordido is a Research Fellow in the Somlo Lab at the Yale School of Medicine, Yale University. His research focuses on the molecular pathogenesis of polycystic kidney disease (PKD), with emphasis on polycystin signaling, cystogenesis mechanisms, and therapeutic development. He holds a PhD in Molecular Medicine (2021) from the University of Santiago de Compostela, following a Master’s in Biomedical Research (2015) and BSc in Biology (2014).
His current research spans three core areas: 1) Polycystin-1 function and localization, 2) Pkd1/Pkd2 re-expression in mouse models, and 3) identification of downstream targets of Pkd1/2 inactivation. His work integrates genetic, molecular, and proteomic approaches to uncover therapeutic pathways for PKD.
Recent publications highlight his contributions to understanding extracellular matrix dynamics, VEGFR2 signaling inhibition, and Gremlin/Notch pathway interactions in cyst progression. His studies utilize advanced mouse models and 3D cell culture systems to validate novel therapeutic targets. Collaborative efforts include the development of CystAnalyser, a software tool for automated cyst quantification in PKD models.
While no academic awards are explicitly listed, his research has advanced preclinical insights into PKD pathophysiology and potential treatments. He contributes to the Somlo Lab’s interdisciplinary environment, bridging basic science and translational medicine.
