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Pierre Vandergheynst is a Full Professor at the Swiss Federal Institute of Technology Lausanne (EPFL) in the Department of Electrical Engineering, with a courtesy appointment in Computer and Communication Sciences. He serves as EPFL’s Vice-Provost for Education since 2015 and leads the Signal Processing Laboratory 2 (LTS2). His research spans harmonic analysis, sparse approximations, mathematical data processing, and applications in signal/image processing, computer vision, machine learning, and graph-based data analysis. PhD in Mathematical Physics (1998), Université catholique de Louvain Postdoctoral Researcher at EPFL (1998-2001) Assistant Professor at EPFL (2002-2007) His research explores geometry/symmetry in high-dimensional data, redundant dictionaries for dimensionality reduction, and computational harmonic analysis on manifolds. Recent work focuses on protein structure modeling, geometric deep learning, and graph-based signal processing. Key article trends include graph neural networks for protein analysis, geometric deep learning in neuroscience, and structured knowledge priors in neural models. His 2023-2025 publications emphasize interpretable AI, long-range dependencies in graphs, and molecular representation learning. Scientific Awards: IEEE Signal Processing Magazine Best Paper Award (2023) Signal Processing Society Best Paper Award (2022) Apple ARTS Award (2007) De Boelpaepe Prize, Royal Academy of Sciences of Belgium (2009-2010) He has supervised over 30 PhD theses and contributed to foundational work in graph signal processing, compressive sensing, and geometric deep learning. His lab develops tools for data science on non-Euclidean structures, with applications in medicine, astronomy, and wireless systems.

• Data Science
• Machine Learning
• Computational Harmonic Analysis
• +6 more

Zhe Ji is an Assistant Professor in the Department of Biomedical Engineering at McCormick School of Engineering and the Department of Pharmacology at Feinberg School of Medicine, Northwestern University. His research integrates computational and experimental genomics to study gene transcription and RNA translation in cell fate commitment and oncogenic processes, aiming to develop precision medicine strategies. **Education**: Postdoctoral Fellow in Cancer Systems Biology, Harvard Medical School Postdoctoral Fellow in Computational Biology, Broad Institute of MIT and Harvard Ph.D. in Computational Genomics, Rutgers University B.S. in Biotechnology, Nanjing University, China **Research Focus**: Keywords include Data Science, Computational Biology, Functional Genomics, RNA, Cancer, Inflammation, and Machine Learning. The lab explores regulatory mechanisms underlying disease, with a focus on translational control, cancer metastasis, and inflammatory networks. **Grants & Advising**: No specific grants or student advisees listed. The lab emphasizes collaborative projects and computational-experimental approaches. **Lab Affiliations**: Zhe Ji’s lab is part of Northwestern’s interdisciplinary environment, bridging engineering and medicine to advance genomic technologies and therapeutic strategies.

• Data Science
• Computational Biology
• Functional Genomics
• +4 more

Dr. John A. Copland III is a Professor of Cancer Biology and Biochemistry & Molecular Biology at Mayo Clinic in Jacksonville, Florida. He leads the Cancer Biology and Translational Research Laboratory, focusing on molecular mechanisms of carcinogenesis, tumor progression, and development of targeted cancer therapies. Education: PhD in Physiology & Endocrinology (Medical College of Georgia), MS in Endocrinology (Medical College of Georgia), BS in Chemistry (Columbus College), with postdoctoral training at University of Texas Medical Branch. Research interests center on: Identifying tumor suppressor genes (e.g., RhoB, TBR3, GATA3) and oncogenes (e.g., FOXO3a, SCD1, NPTX2). Developing patient-derived xenografts and live cell models for personalized medicine. Designing SCD1 inhibitors via in silico modeling for clinical trials. Recent publications highlight his work on SCD1 inhibition in leukemia and thyroid cancer ImmunoPET imaging of thyroid tumors CRISPR-identified drug synergies in cholangiocarcinoma Patient-specific combination therapies using xenograft models

• Cancer Biology
• Molecular Carcinogenesis
• Translational Research
• +3 more

Eduardo Rocha is a Professor and Head of the Microbial Evolutionary Genomics laboratory at the Institut Pasteur, within the Department of Genomes and Genetics. His research integrates bioinformatics, molecular evolution, and genomics to understand bacterial genome organization and dynamics, particularly focusing on mobile genetic elements and their role in adaptation and antibiotic resistance. His research interests include microbial evolutionary genomics, genome organization, horizontal gene transfer, mobile genetic elements (plasmids, phages, integrons), bacterial pathogen evolution, and computational biology. His work lies at the intersection of molecular evolution, population genetics, and molecular epidemiology, with strong translational implications for understanding antimicrobial resistance and infectious disease emergence. The recent publications highlight a consistent focus on mobile genetic elements, genome plasticity, and bacterial adaptation. Key themes include the role of integrons and CRISPR-Cas systems in bacterial immunity, plasmid-mediated spread of antibiotic resistance, phage-plasmid interactions, and the development of bioinformatics tools for microbial genomics. These works frequently appear in high-impact journals such as Science , Nature Microbiology , and PLoS Biology , reflecting significant contributions to the field. Eduardo Rocha leads multiple funded research projects, including ERC-2011-StG EVOMOBILOME, ANR Magisbac, and ANR SHAPE. He has developed and maintains several widely used bioinformatics software tools: IntegronFinder, MacSyFinder, PanACoTA, SatelliteFinder, CapsuleFinder, TXSScan, and others. He mentors a large team of PhD students, postdoctoral researchers, and engineers, and has supervised numerous former students who now hold independent research positions worldwide. Eduardo Rocha has received research funding from major agencies including the European Research Council (ERC) and the French National Research Agency (ANR). His work is central to the LabEx IBEID and the INCEPTION convergence program, where he serves on the steering committee, promoting interdisciplinary research in infectious disease emergence. His laboratory, part of the Genomes and Genetics department, actively contributes to microbial evolutionary genomics through both methodological development and biological discovery. The team participates in networks such as Phages.fr, GDR BIM, and GDR AIEM, reinforcing its collaborative and integrative approach.

• Microbial Evolutionary Genomics
• Genome Organization
• Mobile Genetic Elements
• +13 more

Brinton Seashore-Ludlow is an Associate Professor at the Department of Oncology-Pathology, Karolinska Institute (KI), where he serves as team leader in Olli Kallioniemi's research group and group leader of the biology team at Chemical Biology Consortium Sweden (CBCS), SciLifeLab's national infrastructure. PhD in Biochemistry, KTH Royal Institute of Technology (2012) MSc in Chemical Biology, California Institute of Technology (2007) BA in Biochemistry, Macalester College (2001) His research bridges precision medicine and cancer biology through: Developing ex vivo patient-derived models for drug response prediction Molecular determinants of therapeutic efficacy Integration of high-content imaging with translational studies Focus on ovarian, breast, and pediatric cancers AI-driven analysis of drug sensitivity data Recent articles demonstrate: 3D tumor spheroid platforms for drug testing Epigenetic regulators in neuroblastoma Microfluidics for high-throughput assays Cancer-stroma interactions in treatment resistance Clinical validation of precision diagnostics He co-organizes the Overview Course in Cancer Drug Discovery at KI and leads projects funded by the Swedish Childhood Cancer Foundation.

• Precision Medicine
• Cancer Biology
• Drug Discovery
• +5 more

Prof. Dr. Ralph Bock serves as Director of Department 3: Organelle Biology, Biotechnology and Molecular Ecophysiology at the Max Planck Institute of Molecular Plant Physiology in Potsdam, Germany, where he also leads the Organelle Biology and Biotechnology research group. Previously, he held positions as C4 Professor for Plant Biochemistry and Biotechnology at the University of Münster (2001-2004) and Group Leader at the Institute of Biology III, University of Freiburg (1996-2001). His academic credentials include: Habilitation: University of Freiburg, 1999 Doctorate: University of Freiburg, 1996 Diploma: University of Halle, 1993 Prof. Bock's research focuses on plant molecular biology with particular emphasis on chloroplast biology, organelle biotechnology, and molecular ecophysiology. His work spans genetic engineering of plastids, photosynthesis research, plant biotechnology applications, and understanding organelle-nucleus communication. He has made significant contributions to developing chloroplast transformation systems and applying them to molecular farming, metabolic engineering, and understanding fundamental processes in plant cell biology. His research has important implications for sustainable agriculture, bioenergy, and pharmaceutical production, particularly through the development of plant-based systems for producing vaccines and therapeutic proteins. Analysis of Prof. Bock's recent publications (2023-2025) reveals a strong focus on chloroplast biology, genetic engineering, and molecular farming applications. His work spans fundamental research on organelle genetics, photosynthesis, and stress responses, as well as applied research on using plant and algal systems for biopharmaceutical production. A notable trend is the increasing use of advanced genetic engineering techniques, including CRISPR-based approaches, to manipulate organelle genomes. His research also shows growing interest in algal systems as alternative expression platforms for molecular farming, particularly red algae like Porphyridium for producing viral antigens and glycoproteins.

• Plant Molecular Biology
• Chloroplast Biology
• Organelle Biotechnology
• +7 more

Miler T. Lee is an Associate Professor at the University of Pittsburgh , focusing on gene regulation during early embryonic development through high-throughput experimental and computational genomics. He earned his Ph.D. in Genomics and Computational Biology in 2009 from the University of Pennsylvania under Dr. Junhyong Kim, followed by postdoctoral work with Dr. Antonio Giraldez at Yale University. Joining the university in 2016, his research spans maternal-to-zygotic transition (MZT), RNA stability, pluripotency networks, and evolutionary developmental biology, utilizing model organisms like zebrafish, Xenopus, and Hydractinia symbiolongicarpus. Key Research Themes: Maternally inherited RNA dynamics during embryogenesis Mechanisms of RNA degradation and transcriptome remodeling Evolution of pluripotency networks in hybrid species Role of zinc signaling in fertilization barriers Computational tools for RNA regulation and sensing Scientific Awards: Pan-American Society for Evolutionary Developmental Biology Junior Faculty Award (2024) Outstanding New Investigator – International Xenopus Board (2023) Basil O'Connor Scholar – March of Dimes (2017-2019) Recent publications highlight his work on enhancer classification, RNA degradation mechanisms, and cross-species MZT comparisons. His lab develops innovative methods like RESA for regulatory sequence analysis and studies evolutionary divergence in RNA localization patterns. While the articles span computational and experimental approaches, they consistently address RNA's role in cellular identity, developmental timing, and evolutionary adaptation. Applications include understanding pluripotency, designing RNA biosensors, and elucidating fertilization barriers. Prospective Ph.D. students are encouraged to contact him for opportunities in gene regulation, development, evo-devo, and computational genomics.

• Gene Regulation
• Developmental Biology
• Computational Genomics
• +9 more

Markus Riessland is an Assistant Professor at Stony Brook University’s Renaissance School of Medicine, part of the Empire Innovation Program focused on the Aging Brain. He holds a PhD from the University of Cologne, Germany, specializing in molecular biology, neuroscience, and neurodegenerative diseases. His research centers on cellular senescence in neurons, particularly post-mitotic dopaminergic neurons linked to Parkinson’s disease. He discovered that these neurons can undergo senescence, a process typically absent in non-dividing cells, which has implications for aging and neurodegeneration. Dr. Riessland’s lab employs stem cell models, mouse studies, and advanced sequencing techniques (TRAP-seq, RNA-seq) to investigate senescence mechanisms, identify genetic modifiers influencing neuronal vulnerability, and explore therapies to counteract senescence-driven pathology. His work bridges molecular biology and clinical implications, emphasizing translational approaches for age-related diseases. Notable achievements include an F1000 Exceptional Rating for his 2017 Cell Stem Cell paper and an AJHG Editor’s Corner Highlight for his ribosome profiling study. His research has led to insights on SATB1’s role in senescence, lipid-driven senescence in dopaminergic neurons, and midbrain inflammation in Parkinson’s. Collaborative efforts span international projects on SMA and neuroprotective modifiers like Neurocalcin Delta. While no students are listed here, his work impacts therapeutic development in neurodegenerative diseases through senolytic strategies and genetic interventions. Education: PhD in Molecular Biology from University of Cologne, Germany. Awards: F1000 Exceptional Rating (2017), AJHG Editor’s Corner Highlight (2017). Labs/Teams: Leads research on neuronal senescence mechanisms and therapeutic targets, integrating stem cell biology and systems biology approaches.

• Cellular Senescence
• Neurodegenerative Diseases
• Parkinson's Disease
• +3 more

Ralf Zimmer is a Full Professor for Practical Informatics and Bioinformatics at Ludwig Maximilian University of Munich (LMU) since 2001, affiliated with the Department of Informatics in the Faculty of Mathematica, Informatics and Statistics. He concurrently serves as Head of Section III and Head of the Research Group Network Regulation and Modeling / Machine Learning at the Leibniz Institute for Food Systems Biology at TUM (Leibniz-LSB@TUM) in Freising, Germany. His academic foundation includes a Diploma with distinction in Computer Science, Applied Mathematics and Operations Research from the University of Bonn (1981-1986), followed by a summa cum laude Doctorate in Computer Science and Applied Mathematics from CAU Kiel in 1990, where he received dual honors: the CAU Dissertation Award and Best Dissertation Award. Zimmer's research pioneers the integration of bioinformatics, systems biology, and machine learning to decode molecular food-consumer interactions. His group develops causal system models for biological networks, validated through in silico simulations and multi-omics perturbation experiments (transcriptomics/proteomics). Core methodologies include network regulation modeling, algorithmic bioinformatics, and database construction linking food compounds to biochemical networks and cellular phenotypes, with translational goals for food and biotech innovation. His 14 most recent publications (2012-2024) reveal dominant trends in multi-omics immunology and cardiovascular research, featuring computational innovations for high-throughput data analysis. Key themes include host-pathogen dynamics (viral infections), inflammatory disease mechanisms (atherosclerosis), and methodological advances in proteomics/transcriptomics, consistently bridging fundamental bioinformatics with clinical applications. Major scientific recognitions include: CAU Dissertation Award and Best Dissertation Award (1990) Director of LMU's Informatics Department (2010-2012) DFG Review Board membership for biomedical foundations (2008-2016) Leadership of the DFG Bioinformatics Munich Center (2001-2008) Academic Senate election at LMU München (2011) Zimmer directs LMU/TUM's joint B.Sc./M.Sc. bioinformatics programs since 2001 as founding architect of the DFG-funded Bioinformatics Munich initiative. His educational leadership spans spokesperson roles for international training groups (IRTG RECESS), collaborative research centers (SFB1123 Atherosclerosis), and elite programs (Data Science, Munich Center for Machine Learning). Grant stewardship includes directing the DFG Bioinformatics Munich Center and shaping national funding policy via the DFG review board. At Leibniz-LSB@TUM, his research group pioneers databases connecting food compounds to cellular phenotypes through molecular networks, collaborating with Munich universities, clinics, and biotech partners to develop high-throughput sequencing/proteomics applications for future food and health innovations.

• Bioinformatics
• Systems Biology
• Machine Learning
• +5 more

Jonathan Weissman is a Professor of Biology at the Massachusetts Institute of Technology (MIT) and a Member of the Whitehead Institute. He is also an Investigator of the Howard Hughes Medical Institute and the Landon T. Clay Professor of Biology. His research spans protein folding mechanisms, ribosome profiling, CRISPR-based tools (CRISPRi/a), and genetic interaction mapping. Whitehead Institute Member MIT Professor HHMI Investigator Co-founder, Maze Therapeutics & KSQ Therapeutics Research Interests focus on: Protein folding in cellular contexts Endoplasmic reticulum (ER) function and stress responses Genome-wide CRISPR screening for gene regulation High-density genetic interaction maps in mammals Mitochondrial protein targeting and quality control Epigenomic engineering with synthetic tools Scientific Awards include: Protein Society Irving Sigal Young Investigator Award (2004) Raymond & Beverly Sackler Prize (2008) National Academy of Sciences election (2009) NAS Award for Scientific Discovery (2015) Genetics Society of America Ira Herskowitz Award (2020) Labs & Collaborations : Leads the Weissman Lab at MIT/Whitehead Institute, co-leads the Laboratory for Genomic Research with GlaxoSmithKline, and chairs the Stowers Institute Scientific Advisory Board.

• Protein Folding
• Systems Biology
• Genomics
• +6 more

Yulong Wei is a Researcher in the Department of Microbial Pathogenesis at Yale School of Medicine. His work focuses on understanding viral persistence mechanisms, particularly in HIV-1 and SARS-CoV-2, using cutting-edge genomic and immunological approaches. He explores how host cellular environments influence viral integration, reservoir formation, and immune evasion. Research interests include: HIV reservoir dynamics and latency mechanisms Host-pathogen interactions in viral persistence Single-cell multiomics analysis of viral infections Antiviral drug discovery and repurposing Ribosomal adaptation and translation mechanisms in bacteria Recent work highlights his contributions to understanding how interferon signaling and chromatin structure affect HIV integration sites, as well as computational studies of griseofulvin's potential in combating SARS-CoV-2. He has also investigated evolutionary genomic signatures in microbes related to translation efficiency and environmental adaptation. His lab is part of the Yale School of Medicine's broader efforts in microbial pathogenesis and infectious disease research, with a focus on translational applications for persistent viral infections.

• HIV Research
• Virology
• Immunology
• +3 more

Susanne Bornelöv is a Professor in the Department of Biochemistry at the University of Cambridge. Her research focuses on computational genomics and gene regulation, particularly exploring posttranscriptional mechanisms such as codon optimality-mediated mRNA decay and transposon silencing. She uses computational methods, ribosome profiling, and Drosophila models to study how codon usage, tRNA availability, and RNA modifications influence gene regulation and genome evolution. Her work integrates artificial intelligence (AI) and comparative genomics to model gene regulatory processes and design novel regulatory elements. Key research areas include piRNA clusters' roles in suppressing retroviruses, codon usage bias in pluripotent stem cells, and the interplay between mRNA methylation and protein synthesis. The Bornelöv Group collaborates widely, including with institutions like Cold Spring Harbor Laboratory, to advance understanding of fundamental gene expression principles. Publications highlight contributions to topics like deep learning in genomics, evolutionary conserved piRNA mechanisms, and transcriptional regulation. She leads a group open to interns, students, and researchers, fostering interdisciplinary approaches to address complex biological questions.

• Computational Genomics
• Gene Regulation
• RNA Biology
• +4 more

Prof. Dr. Kirsten Jung is a faculty member at the Department of Microbiology , Faculty of Biology , Ludwig Maximilian University of Munich . Her research focuses on bacterial signal transduction, stress response mechanisms, and systems biology approaches to understand microbial regulatory networks. Key research areas include stress-dependent gene expression in bacterial populations Structural and functional analysis of membrane-integrated receptors Metabolism-based chemical communication in bacteria Integration of experimental and computational systems biology Recent publications highlight her lab's work on Escherichia coli epitranscriptomic modifications under heat stress, m 5 C rRNA dynamics, and the role of RNA methylation in host-pathogen interactions. Collaborative studies address bacterial acid stress responses and their implications for antibiotic tolerance. Her interdisciplinary work bridges microbiology with ecological studies, as evidenced by research on biodiversity conservation in forest and urban ecosystems. Publications also demonstrate expertise in advanced imaging techniques (e.g., arterial spin labeling for glioma analysis) and bioinformatics approaches. Current advisees include Gloria Gessinger and Tania P. Gonzalez-Terrazas . She can be contacted at jung@lmu.de .

• Bacterial Signal Transduction
• Stress Response Mechanisms
• Membrane Protein Structure-Function Analysis
• +3 more

Gustavo Alberto Nader is a Professor of Kinesiology at The Pennsylvania State University , holding the Dorothy Foher and J. Lloyd Huck Chair in Molecular, Cellular and Integrative Physiology. His research focuses on skeletal muscle growth control , ribosome biogenesis , and transcriptional/epigenetic regulation in health and disease contexts. Affiliated with the Huck Institutes of the Life Sciences and College of Health and Human Development Principal Investigator on NIH-funded projects examining ribosomal control of muscle mass Research Interests span molecular mechanisms of muscle adaptation to exercise, cancer cachexia, chronic disease impacts on muscle, and cross-species Wnt signaling regulation by CO₂ levels. Key methodologies include human/animal/cell models, ribosomal analysis, and epigenetic profiling. Publication Trends show sustained focus on: Ribosome biogenesis in muscle hypertrophy (2012–2025) Cancer-induced muscle wasting mechanisms (2015–2024) CO₂/Wnt pathway interactions (2015–2019) Exercise-induced transcriptional responses (2001–2016) Scientific Awards include the Huck Chair, while his Grants & Collaborations involve NIH-funded studies on transcriptional/epigenetic mechanisms (2019–2026) with cross-disciplinary teams in physiology, oncology, and respiratory medicine.

• Skeletal Muscle Physiology
• Ribosome Biogenesis
• Transcriptional Regulation
• +4 more

John Prensner is an Assistant Professor in the Department of Pediatrics - Hematology Oncology at the University of Michigan. He is a physician-scientist and pediatric hematologist/oncologist specializing in childhood brain tumors, particularly medulloblastoma and diffuse intrinsic pontine glioma. Education: Tufts University (BS 2005), University of Michigan (MD/PhD 2014) Clinical training: Boston Combined Residency, Boston Children's Hospital/Dana-Farber Cancer Institute fellowship Postdoctoral research: Broad Institute of MIT and Harvard His research focuses on: Molecular mechanisms of childhood brain cancers Synthetic lethality in cancer genomics Metabolic dependencies in Group-3 medulloblastoma Non-canonical RNA translation and microproteins in oncogenesis CRISPR screening for therapeutic targets Recent work highlights PELO as a synthetic lethal target in 5% of adult cancers and metabolic vulnerabilities in medulloblastoma, including cuproptosis mechanisms. Collaborations include: @LyssiotisLab (metabolism) @vennetilab @CancerDepMap Carl Koschmann Paul Northcott Deepak Nagrath

• Childhood Brain Tumors
• Medulloblastoma
• Atypical Teratoid/Rhabdoid Tumor
• +8 more