Jonathan Weissman

Jonathan Weissman is a Professor of Biology at the Massachusetts Institute of Technology (MIT) and a Member of the Whitehead Institute. He is also an Investigator of the Howard Hughes Medical Institute and the Landon T. Clay Professor of Biology. His research spans protein folding mechanisms, ribosome profiling, CRISPR-based tools (CRISPRi/a), and genetic interaction mapping.

• Whitehead Institute Member
• MIT Professor
• HHMI Investigator
• Co-founder, Maze Therapeutics & KSQ Therapeutics

Research Interests focus on:

• Protein folding in cellular contexts
• Endoplasmic reticulum (ER) function and stress responses
• Genome-wide CRISPR screening for gene regulation
• High-density genetic interaction maps in mammals
• Mitochondrial protein targeting and quality control
• Epigenomic engineering with synthetic tools

Scientific Awards include:

• Protein Society Irving Sigal Young Investigator Award (2004)
• Raymond & Beverly Sackler Prize (2008)
• National Academy of Sciences election (2009)
• NAS Award for Scientific Discovery (2015)
• Genetics Society of America Ira Herskowitz Award (2020)

Labs & Collaborations: Leads the Weissman Lab at MIT/Whitehead Institute, co-leads the Laboratory for Genomic Research with GlaxoSmithKline, and chairs the Stowers Institute Scientific Advisory Board.