Richard Cornall

Richard Cornall is the Nuffield Professor of Clinical Medicine at the University of Oxford and Head of the Nuffield Department of Clinical Medicine. He is also a Professor of Immunology and an MRC Investigator, affiliated with Magdalen College, Oxford.

• Major research focus: understanding immune system formation, regulation, and causes of autoimmunity, particularly systemic autoimmune diseases.
• Collaborates with Professor Simon Davis on lymphocyte engineering for cancer and inflammation.
• Uses transgenic models to study genetic susceptibility to autoimmunity and immunodeficiency.

His research explores how adverse immune reactions to self/foreign antigens cause disease burden and how natural selection maintains genetic variation in immune responses.

Recent publications address:

• T cell activation in prolidase deficiency and lupus-like autoimmunity
• B cell requirement for DOCK8 in T cell help integration
• Immune checkpoints in autoimmunity
• SARS-CoV-2 antibody prevalence and neutralization
• Hypoxia-inducible factor regulation in B cell development
• ZIP7 zinc transporter's role in B cell biology

Scientific Awards:

• Fellow of the Royal College of Physicians (FRCP)
• Fellow of the Academy of Medical Sciences (FMedSci)

Collaborations span institutions including Australian National University, UCSF, NIH, University of Bristol, Newcastle University, and Weatherall Institute of Molecular Medicine.