جستجوی استاد راهنمای دانشگاهی

Dr. Min Xu is a Courtesy Professor in the Computational Biology Department within the School of Computer Science at Carnegie Mellon University. His research focuses on advancing computer vision and machine learning for biomedical image analysis, particularly cellular cryo-electron tomography (Cryo-ET) and automated science video analysis. He leads a lab developing cutting-edge computational tools for structural biology and medical imaging. Key research directions include: High-resolution 3D Cryo-ET image analysis AI-driven medical image segmentation Few-shot learning for cryo-EM analysis Video analysis frameworks for laboratory automation Notable contributions include the AITom toolkit for Cryo-ET analysis and pioneering work in adapting foundation models for medical imaging tasks. His work has been published in top venues like CVPR, MICCAI, and Nature-associated journals. No academic awards or grants are explicitly listed in the provided text. He maintains an active lab focused on translating computational methods into impactful biomedical research tools.

• Biomedical Image Analysis
• Computer Vision
• Machine Learning
• +۴ مورد دیگر

Dr. Jamie Warner is a Professor and Temple Foundation Endowed Professor in the Walker Department of Mechanical Engineering at The University of Texas at Austin, leading the TMI Electron Microscopy Facility within the Cockrell School of Engineering. His research focuses on nanostructured materials, advanced transmission electron microscopy, and opto-electronic applications. Prior to UT Austin, he held a Full Professorship at the University of Oxford's Department of Materials, where he led the Nanostructured Materials Group and graduated 30 PhD students. Key roles include Director of the Texas Materials Institute and Visiting Professorships at MIT and Sungkyunkwan University. Education: PhD in Physics (University of Queensland, 2004), Postdoc (New Zealand/Australia, 2005-2006) Research Interests: Atomic-scale characterization of 2D materials (graphene, MoS₂, WS₂), electron microscopy techniques, nanoelectronic devices, and energy storage materials. His articles span advanced TEM techniques, 2D material synthesis, and opto-electronic device fabrication. Notable awards include the Royal Society University Research Fellowship (2010), ERC Consolidator Grant (2017), and ACS Nano Lectureship (2019). Awards: Fellow of the Royal Society of Chemistry (2019), Top 10 'Highly Prolific' ACS Nano Author (2018) Advising: 30+ PhD graduates, extensive postdoc and master's supervision Grants: ERC Consolidator Grant for opto-electronics, multiple industry and academic collaborations He leads the Warner Group, which operates cutting-edge facilities for electron microscopy and nanofabrication. Current projects include cryo-TEM for battery materials and single-atom catalysts.

• Nanostructured Materials
• Advanced Transmission Electron Microscopy
• 2D Materials
• +۵ مورد دیگر

Daniel Sage is a Lecturer and Scientific Advisor at École polytechnique fédérale de Lausanne (EPFL) , affiliated with the Biomedical Imaging Laboratory (LIB) under the College of Engineering (STI) and School of Life Sciences (SV) . He specializes in bioimage informatics , structured-illumination microscopy , and deep learning applications for biomedical imaging. His work spans algorithm development for single-molecule localization microscopy (SMLM) , fluorescence imaging , and 3D reconstruction . His research group has developed open-source tools like FlexSIM for light inhomogeneity correction, DeepImageJ for integrating deep learning in ImageJ, and Steer'n'Detect for orientation-accurate template detection. His publications focus on correcting multiple-blinking artifacts in PALM, optimal transport metrics for SMLM evaluation, and contextual feature analysis for xenograft cell classification. He mentors PhD students and contributes to interdisciplinary education through courses such as Bioimage Informatics and Fundamentals of Image Analysis , emphasizing practical software solutions and Java programming for bioimage processing. His collaborations include institutions like Howard Hughes Medical Institute and Centre National de la Recherche Scientifique (CNRS) .

• Biomedical Imaging
• Image Processing
• Deep Learning Applications
• +۵ مورد دیگر

Silvia Cavagnero is a Professor in the Department of Chemistry at the University of Wisconsin–Madison, with a research focus on protein folding and misfolding in cellular contexts. Her work integrates biomolecular spectroscopy, chemical biology, and computational methods to address fundamental questions in structural biology. B.S., First University of Rome ‘La Sapienza’ (1988) M.S., University of Arizona (1990) Ph.D., California Institute of Technology (1996) Her research explores the role of molecular chaperones like Hsp70 in protein biogenesis, the development of laser-driven NMR techniques for enhanced sensitivity, and the implications of protein aggregation in neurodegenerative diseases. Key projects include cotranslational folding studies at ribosomal exit tunnels and hyperpolarization methods for low-concentration NMR analysis. The 15 most recent publications highlight interdisciplinary advances in NMR spectroscopy optimization Protein folding kinetics Cryo-EM structural analysis Chaperone-client interactions Hsp70 antimicrobial design Hydration dynamics in folding Scientific contributions include A Prize for Going in Vivo (2017) Recognition for Diversity and Inclusion Efforts Students from the Cavagnero Group have pursued careers in academia, pharmaceutical industries, and national laboratories. Her lab emphasizes interdisciplinary training, blending physical chemistry, biology, and computational analysis.

• Protein Folding
• Biomolecular Spectroscopy
• Neurodegenerative Diseases
• +۴ مورد دیگر

Professor Chris Greening is a Research Professor in the Department of Microbiology at Monash University, leading the One Health Microbiology group at the Biomedicine Discovery Institute. He holds a first-class degree in Molecular and Cellular Biochemistry from the University of Oxford (2010) and a PhD from the University of Otago (2013). His career includes postdoctoral roles at Otago, CSIRO, and the Australian National University, followed by appointments as a group leader in Monash’s School of Biological Sciences (2016) and a medically-focused NHMRC EL2 Fellow in the Department of Microbiology (2020). Research Focus: Bacterial persistence mechanisms, microbial metabolism, antimicrobial resistance (AMR), and One Health approaches linking environmental, clinical, and public health challenges. Awards: Fenner Medal (2022) and Jim Pittard Award (2019). Key Projects: RISE, Global Research Alliance on Agricultural GHGs, SAEF, and the ARC Carbon Utilisation Hub. Leads Monash’s AMR R&D Facility. Research spans metabolic pathways enabling bacterial survival in extreme conditions (e.g., hydrogen oxidation, F420 cofactor roles), climate impacts (greenhouse gas regulation), and translational programs addressing diarrheal diseases and AMR. Grants: ARC DECRA Fellowship, NHMRC EL2 Fellowship. Cross-disciplinary collaborations with engineers, ecologists, social scientists, and industry. Lab facilities include advanced microbiology, structural biology, and systems biology tools. Contributions align with UN SDGs: climate action (SDG13), good health (SDG3), and sustainable cities (SDG11).

• Microbial Metabolism
• Antimicrobial Resistance
• Environmental Microbiology
• +۵ مورد دیگر

Ulrich Vogt is a Professor in Applied Physics at Kungliga Tekniska Högskolan (KTH) and leads the X-ray Optics and Nanoimaging group within the Bio-Opto-Nano unit. He serves as Vice-head of the Applied Physics department for undergraduate education. His research focuses on developing advanced X-ray microscopy techniques, particularly at synchrotron facilities like MAX IV’s NanoMAX beamline. He specializes in X-ray optics, nanoimaging, and diffractive optical elements for applications in materials science, biology, and medicine. Key contributions include the design of the NanoMAX beamline, optimization of X-ray zone plates via metal-assisted chemical etching, and advancements in multi-beam ptychography. Vogt has pioneered compact X-ray microscopy systems using laser-plasma sources and liquid-jet targets. His work integrates nanofabrication, computational imaging, and synchrotron instrumentation to achieve sub-100 nm resolution in hard and soft X-ray regimes. Teaching responsibilities include courses on experimental physics, photonics, and X-ray applications. His lab collaborates internationally on projects like the European XFEL, emphasizing high-brightness sources and radiation-resistant optics. Recent innovations include adaptive multi-beam ptychography and stereo X-ray imaging for 3D nanoscale visualization. Research highlights span over 100 peer-reviewed articles, with a focus on coherence characterization, beamline instrumentation, and nanostructured materials. Vogt’s grants include a Röntgen-Ångström Cluster award supporting multi-beam ptychography and cryo-microscopy advancements.

• X-ray Optics
• Nanoimaging
• Synchrotron Radiation
• +۳ مورد دیگر

Tina Izard, Ph.D., serves as a Professor at The Scripps Research Institute in Jupiter, Florida, leading the SR-CHEM-IZARD LAB. Her institutional affiliation includes a business mailing address at 130 SCRIPPS WAY # 2C1, Jupiter, FL 33458 (Location C234) and a business phone number (561) 228-2000. The laboratory was equipped with a cryoARM300 electron microscope installation in 2020, indicating a strong focus on high-resolution structural analysis techniques. Her research centers on the molecular mechanisms of environmental toxicants, particularly their disruption of integrin-mediated cell signaling within specialized membrane microdomains known as lipid rafts. This work bridges environmental health sciences with structural biochemistry, investigating how pollutants interfere with fundamental cellular communication pathways. Her approach integrates cryo-electron microscopy with biochemical assays to visualize and quantify toxicant-induced alterations in protein complexes involved in cell adhesion and signal transduction. Dr. Izard's 2025 publication in BioEssays exemplifies her research trajectory, demonstrating how environmental contaminants target lipid raft-organized signaling hubs. This work reveals novel mechanisms by which toxicants dysregulate integrin function, with implications for understanding environmental contributions to diseases involving cellular adhesion defects. Her research consistently emphasizes the structural basis of toxicant interactions with membrane-associated protein complexes. No scientific awards or honors were documented in the provided source material. While no student advisees or specific grant funding are listed in the available information, Dr. Izard directs the SR-CHEM-IZARD LAB, which maintains advanced cryo-electron microscopy capabilities. The laboratory's infrastructure supports structural investigations of protein-membrane interactions, with ongoing research focused on elucidating the molecular architecture of signaling complexes vulnerable to environmental disruption. Current work appears to be developing structural models of toxicant-bound integrin complexes to identify potential intervention points.

• Environmental Toxicology
• Integrin Signaling
• Biochemistry
• +۳ مورد دیگر

Professor Guillermo Montoya is a Research Director and Group Leader at the Protein Structure & Function Program of the Novo Nordisk Foundation Center for Protein Research (CPR), University of Copenhagen, Denmark. His work focuses on unraveling cellular mechanisms at the atomic level through advanced methodologies including X-ray crystallography and cryo-electron microscopy. PhD in Chemistry, University of Zaragoza (1989–1993) MSc in Biochemistry, University of the Basque Country (1984–1989) Montoya's research spans Structural Molecular Biology and Genome Integrity , with specific emphasis on: Activation mechanisms of oligomeric kinases CRISPR-Cas12a conformational dynamics Macromolecular complexes in telomere maintenance His publications reveal significant contributions to CRISPR-Cas systems , kinase activation , and DNA/RNA degradation mechanisms . Scientific Awards: EMBO Member (2018) Spanish National Prize in Biomedicine (2009) Multiple Fellowships (EMBO, Marie Curie, FEBS, Marie Curie) Montoya's group integrates structural biology with cell biology to address fundamental questions in genome stability and biomedical applications. His work has been cited over 188 times for studies on CRISPR-Cas endonucleases and has attracted attention from 41 patents.

• Genome Integrity
• Structural Molecular Biology
• CRISPR-Cas Systems
• +۳ مورد دیگر

Hartmut Michel is a Scientific Member and Director at the Max Planck Institute of Biophysics in Frankfurt, Germany, where he leads the Department of Molecular Membrane Biology. He has held this position since 1987 and has also served as an Adjunct Professor at the University of Frankfurt since 1989. Michel received his PhD in Biochemistry from the University of Wuerzburg in 1977 and completed postdoctoral work there before joining the Max Planck Institute of Biochemistry as a research associate. Michel's research focuses on membrane proteins, particularly in the areas of structural biology, biochemistry, photosynthesis, and respiratory complexes. His work has centered on understanding the structure and function of membrane proteins, especially cytochrome c oxidase and photosynthetic reaction centers. He pioneered techniques for membrane protein crystallization and has made significant contributions to understanding electron transfer processes and proton pumping mechanisms in respiratory enzymes. His publication record spans over four decades, with recent work focusing on cryo-EM structural analysis of membrane proteins including cytochrome bd oxidases, ABC transporters, and photosynthetic complexes. The research demonstrates a consistent trajectory from fundamental structural studies toward understanding functional mechanisms and applications in areas like antibiotic development and bioenergetics. Scientific Awards 1986 Leibniz Prize of the German Research Foundation 1988 Otto Bayer Prize (with Johann Deisenhofer) 1988 Nobel Prize in Chemistry (with Johann Deisenhofer and Robert Huber) 2008 Keilin Medal of the British Biochemical Society Honorary doctorates from the Universities of Wuerzburg and Bologna Michel has maintained an active research program with numerous collaborations across Europe and internationally. His laboratory has developed innovative approaches for membrane protein expression, purification, and structural characterization. The team has made significant contributions to understanding the structure-function relationships in respiratory chain components and photosynthetic apparatus. His department at the Max Planck Institute serves as a leading center for membrane protein research, with specialized facilities for protein crystallization, cryo-electron microscopy, and functional characterization of membrane proteins. The research has implications for understanding fundamental biological energy conversion processes and developing new therapeutic approaches targeting membrane proteins.

• Membrane Proteins
• Structural Biology
• Biochemistry
• +۵ مورد دیگر

Hongyi Xu is a Senior Lecturer at the Australian National University's Research School of Chemistry and a researcher/principle investigator at Stockholm University (0.2 FTE). He holds a PhD in Materials Engineering from the University of Queensland (2013) and a Bachelor of Engineering (Mechatronics) from the same institution (2008). His research focuses on developing electron crystallography methods for studying materials, small molecules, peptides, and macromolecules, with applications in drug design and structural biology. He has pioneered MicroED techniques, including solving the first new protein structure using this method and demonstrating protein-inhibitor binding analysis. Key research areas include electron crystallography methodology, multidimensional electron microscopy toolkits, metalloenzyme charge state analysis, and fragment-based drug design. He has secured grants such as the Swedish Research Council Starting Grant and has collaborated with over 25 international groups. Notable achievements include the development of SerialED and contributions to cryo-EM advancements like Single Particle Analysis (SPA) and cryo-ET. Recent publications highlight advancements in perovskite photovoltaics, electrocatalytic hydrogen peroxide production, and zeolite structural analysis. His work bridges materials science and biology, addressing challenges in structural determination through innovative microscopy techniques. Awards include the Dean’s Accommodation for Academic Excellence (2013) and the Best Thesis Award (2013).

• Electron Crystallography
• Biomolecular Structure Determination
• Material Science
• +۳ مورد دیگر

Lori Passmore is a Research Fellow at the Medical Research Council Laboratory of Molecular Biology (MRC-LMB), part of the University of Cambridge's School of Clinical Medicine. Her work focuses on understanding the molecular mechanisms of multi-protein complexes involved in gene expression regulation and DNA repair. Studied pre-mRNA 3′-end processing via the Cleavage and Polyadenylation Factor (CPF) complex Investigated DNA crosslink repair through the Fanconi Anemia pathway Developed cryo-EM methodologies for structural analysis Her laboratory employs a hybrid approach combining electron cryo-microscopy , X-ray crystallography, biochemical assays, and genetic techniques to elucidate complex architectures and functional dynamics. Notable discoveries include structural insights into the FANCD2-FANCI complex and mechanisms of poly(A) tail length regulation. Current research spans topics such as: 3′-end processing coordination mRNA deadenylation pathways DNA replication stress responses Protein complex assembly principles Lori Passmore's group includes trainees and staff studying these fundamental biological processes. Their work contributes to understanding gene regulation, RNA metabolism, and DNA repair mechanisms critical for preventing diseases like cancer.

• Molecular Biology
• Biochemistry
• Structural Biology
• +۵ مورد دیگر

Professor Stephan A. Sieber is a leading researcher in bioorganic chemistry at the Technical University of Munich (TUM), where he holds the Chair of Organic Chemistry II within the TUM School of Natural Sciences. His research program focuses on developing new drugs against multidrug-resistant bacteria through a multi-disciplinary approach that integrates synthetic chemistry, functional proteomics, microbiology, and protein biochemistry. His laboratory has made significant contributions to identifying unprecedented antibacterial targets beyond the scope of current antibiotics and exploiting these for chemical manipulation. Recent work has increasingly incorporated machine learning approaches to accelerate antibiotic discovery, with notable publications on AI-guided pipelines, drug-target interaction prediction, and high-throughput screening optimization. Sieber's research has resulted in the discovery of new active substances, some of which are currently being optimized for medical applications. His group's publications reveal a strong focus on chemical proteome mining, natural product mode of action studies, and novel antibacterial target identification. The lab has published extensively in top journals including Nature Chemistry, Nature Communications, and ACS Central Science. Inhoffen Medal (2024) Max Bergmann Medal (2023) ERC Advanced Grant (2023) Merck Future Insight Prize (2020) Klaus Grohe Prize (2020) ERC Consolidator Grant (2016) Professor Sieber leads an active research group that maintains a strong presence in the scientific community through regular publications, conference presentations, and collaborations. His laboratory website and BlueSky presence (@sieberlab.bsky.social) demonstrate ongoing research activities and engagement with the broader scientific community. He has successfully secured significant research funding including multiple ERC grants that have supported his innovative work in antibiotic discovery.

• Bioorganic Chemistry
• Antibiotic Development
• Chemical Proteomics
• +۵ مورد دیگر

Prof. Torsten Ochsenreiter is a Group Leader at the Institute of Cell Biology, University of Bern, and part of the Multidisciplinary Center for Infectious Diseases (MCID). His research focuses on molecular parasitology, particularly on trypanosomes and malaria parasites, utilizing advanced microscopy techniques to study fundamental biological processes. His primary research interests include mitochondrial biogenesis, kinetoplast genome maintenance, RNA editing mechanisms, and cytoskeletal dynamics in Trypanosoma brucei . He investigates how mitochondrial DNA is segregated during cell division and how post-translational modifications regulate parasite transmission. His work bridges cell biology, structural biology, and infectious disease research to understand pathogenic mechanisms in neglected tropical diseases. Analysis of his recent publications reveals a consistent focus on the tripartite attachment complex (TAC), mitochondrial genome inheritance, and expansion microscopy applications. His research demonstrates how structural adaptations in parasite organelles enable survival and transmission, with significant implications for developing novel therapeutic strategies against African sleeping sickness and malaria. No scientific awards were mentioned in the provided text. Prof. Ochsenreiter advises students and leads an active research team at the University of Bern. The Ochsenreiter lab provides opportunities for undergraduate and graduate students to engage in cutting-edge parasitology research, though specific grant funding details were not provided in the text. The Ochsenreiter lab operates within the Institute of Cell Biology and specializes in molecular parasitology techniques including expansion microscopy, cryo-electron tomography, and genetic manipulation of trypanosomes. The team investigates mitochondrial biology and cytoskeletal organization to uncover vulnerabilities in parasite life cycles.

• Molecular Parasitology
• Mitochondrial Biogenesis
• Protozoan Parasites
• +۵ مورد دیگر

Julia Chamot-Rooke is a Principal Investigator and Researcher at the Institut Pasteur in Paris, France, affiliated with the Department of Structural Biology and Chemistry and the Mass Spectrometry for Biology unit (UTechS MSBio), a joint CNRS service and research unit (USR2000). She leads multiple projects in advanced proteomics and is the PI for the Institut Pasteur in the European Proteomics Infrastructure Consortium providing access (EPIC-XS). Her research focuses on developing innovative methods in top-down proteomics , cross-linking mass spectrometry , and structural proteomics to study intact proteins, post-translational modifications, and protein complexes. Her work has applications in microbiology, infectious diseases, and host-pathogen interactions. She has developed the ProteoCombiner software to integrate proteomics data for improved proteoform characterization. The recent publications reflect a strong emphasis on structural and functional proteomics , particularly in microbial systems and immune interactions. Trends include the use of advanced mass spectrometry techniques (HDX-MS, cross-linking MS, top-down MS) to investigate protein structure, dynamics, and interactions in pathogens and host systems. There is also a growing focus on software and tool development to enhance data analysis and reproducibility in proteomics. Principal Investigator, EPIC-XS at Institut Pasteur Coordinator, Joint Research Activity on Future and Emerging Proteomics Technologies Lead Developer, ProteoCombiner software She supervises PhD students and research engineers and collaborates widely on projects involving bacterial pathogenesis, immune evasion, and structural biology. Her lab is equipped with state-of-the-art Orbitrap mass spectrometers and participates in transnational access programs, providing cutting-edge proteomics services to the European research community.

• Proteomics
• Structural Biology
• Mass Spectrometry
• +۷ مورد دیگر

Baoyu Chen is an Associate Professor in the Department of Internal Medicine at UT Southwestern Medical Center and a member of its Division of Digestive and Liver Diseases. He holds a bachelor's degree in chemical engineering from Hunan University (China), a master's in biochemistry and molecular biology from Tsinghua University (China), and a doctorate in chemical biology from Pennsylvania State University (USA). His research integrates biochemical, biophysical, computational, and structural approaches to investigate molecular mechanisms linking membrane signaling to cytoskeletal dynamics. Education: BSc in Chemical Engineering, Hunan University, China MS in Biochemistry & Molecular Biology, Tsinghua University, China PhD in Chemical Biology, Pennsylvania State University, USA Research Interests: Dr. Chen’s work focuses on protein assemblies regulating actin polymerization and endosomal trafficking (WAVE, WASH, CCC-Retriever, Retromer complexes) and their roles in cellular processes like migration, adhesion, immune activation, and neural development. His lab employs cryo-electron microscopy and collaborations with clinicians to uncover disease mechanisms. Recent Research Trends: His publications emphasize structural insights into WAVE complex activation, endosomal trafficking regulation, and pathogen hijacking of cytoskeletal systems. These studies span cell biology, structural biology, and synthetic biology applications. Scientific Awards: His work is supported by prestigious grants including the NIH MIRA NSF CAREER Award Professional Affiliations: Active member of American Heart Association American Society for Cell Biology Society for Neuroscience Laboratory: The Stone Chen Lab at UT Southwestern investigates membrane-to-cytoskeleton signaling and its implications in human disease. The lab collaborates with biologists and clinicians and welcomes opportunities for collaboration.

• Cell Biology
• Structural Biology
• Biochemistry
• +۳ مورد دیگر