Anders Nykjær is a Professor at the Department of Biomedicine , Aarhus University , and Director of the DANDRITE - Nykjær Group . His research focuses on the role of VPS10p-domain receptors, particularly sortilin and SorCS2 , in neuronal viability, neurotrophic signaling, and neurodegenerative diseases. University: Aarhus University Department: Department of Biomedicine Lab: DANDRITE - Nykjær Group Nykjær's work spans neurodegenerative diseases (Alzheimer's, Huntington's), neurotrophic factors (BDNF, NGF), and receptor biology . His studies investigate how receptors like sortilin modulate amyloid-beta catabolism, dopaminergic neuron development, and neurovascular coupling. Recent articles highlight SorCS2 in motor neuron development and progranulin interactions. Article trends include neurovascular signaling (SorCS2 in astrocytic function), neurotrophic receptor dynamics (TrkB/GluN2B/SorCS2 complexes), and cardiovascular-neurological cross-talk (sortilin in atherosclerosis and diabetic retinal degeneration). His methods involve in vivo models, proteomics, and receptor-ligand interaction studies. Scientific contributions emphasize receptor biology in Neurodegenerative disease mechanisms Lipoprotein and neurotrophin receptor trafficking Neurovascular and synaptic signaling pathways






