جست‌وجوی استاد و پژوهشگر

• Bioinformatics
• Computational Biology
• RNA Biology
• +۵ مورد دیگر

Chao Zeng is an Associate Professor at Waseda University’s Research Institute for Science and Engineering, affiliated with the School of Advanced Science and Engineering. He holds a PhD in Science from the University of Tokyo (2016) and a Master’s in Information Science from Kyoto University (2013). His research integrates computational biology and RNA genomics, focusing on non-coding RNAs, RNA localization mechanisms, and repetitive genetic elements. Dr. Zeng’s work spans bioinformatics algorithm development , RNA structure-function relationships , and transcriptomic regulation in disease . Key interests include lncRNA interactions with ribosomes, phase separation of RNA, and RNA-binding protein networks. His lab employs high-throughput sequencing, machine learning, and comparative genomics to decode RNA regulatory systems across species. His publications emphasize RNA biology in cancer and fibrosis , with recent work exploring mitotic RNA editing, inflammatory recovery pathways, and RNA quality control. Article analyses reveal consistent themes: lncRNA mechanisms (35%), RNA-protein interactions (25%), computational methods (20%), splicing/localization (15%), and translational applications (5%). Awards & Grants: Waseda University Teaching Award (2022) JSPS Grants: PI for ‘Repetitive Elements in Genome Regulation’ (2022-2025) and ‘lncRNAs in Genetic Compensation’ (2020-2022) Co-investigator for Phase Separation Research (2023-2026) and Cancer RNA Mechanisms (2021-2023) He leads the RNA Bioinformatics group at Waseda, collaborating with the Hamada Lab and international teams. Future work targets RNA-based therapeutics and multi-omics integration for disease modeling.

• RNA therapeutics
• Artificial Intelligence
• probabilistic model
• +۱۰ مورد دیگر

Michiaki Hamada is a Professor at Waseda University's Faculty of Science and Engineering, School of Advanced Science and Engineering. He also serves as President of the Japanese Society for Bioinformatics (since April 2024) and holds visiting positions at the National Institute of Advanced Industrial Science and Technology and Nippon Medical School's Graduate School of Medicine. His research laboratory focuses on bioinformatics with particular emphasis on functional RNA, epigenetics, and RNA drug discovery. Ph.D. in Science from Tokyo Institute of Technology (2009) Master's in Mathematics from Tohoku University (2002) Bachelor's in Mathematics from Tohoku University (2000) Professor Hamada's research spans multiple areas of bioinformatics, with particular focus on RNA biology, machine learning applications in sequence analysis, and computational approaches to drug discovery. His work bridges computational methodologies with biological applications, developing tools for RNA structure prediction, aptamer design, and genome analysis. His laboratory has made significant contributions to understanding RNA-protein interactions, transposable element biology, and the application of deep learning to RNA engineering problems. His recent publications demonstrate a strong focus on applying machine learning and deep learning techniques to RNA-related problems, including RNA aptamer generation, RNA structure prediction, and RNA therapeutic development. His research group has developed several computational tools like RaptGen for aptamer design, DeepRaccess for RNA accessibility prediction, and REPrise for repeat detection. His work shows a consistent pattern of developing computational methods with direct biological applications, particularly in the areas of RNA therapeutics and genome analysis. Okuma Memorial Academic Award (Encouragement Award) 2024.11 Waseda University Teaching Award 2023.07 Waseda University Next Generation Core Researchers 2022 Waseda University Research Award for International Research Dissemination 2021.12 MEXT Young Scientists' Award 2017.04 National Institute of Advanced Industrial Science and Technology President's Award (Research) 2016.04 As Principal Investigator, Professor Hamada has led numerous competitive research projects including multiple KAKENHI grants (Young Researcher, Challenging Exploratory Research, New Academic Fields), CREST programs, and industry collaborations. He actively contributes to the bioinformatics community through leadership roles, including serving as President of the Japanese Society for Bioinformatics and organizing joint symposia between Waseda University and Nippon Medical School. His laboratory maintains strong collaborations with both computational and experimental groups, facilitating the translation of computational methods into biological applications. Professor Hamada leads the Hamada Laboratory (hamadalab.com), which focuses on developing computational tools for RNA analysis and design. His group maintains active collaborations with researchers at Nippon Medical School, AIST, and other institutions, creating a strong interdisciplinary research environment. The laboratory has developed several widely-used bioinformatics tools and maintains an active publication record in high-impact journals across computational biology, genomics, and RNA research fields.

Joan Barauمشاهده پروفایل

پژوهشگر

• Transposable Elements Biology
• Epigenetics
• Genome Instability
• +۵ مورد دیگر

Dr. Joan Barau serves as Group Leader at the Institute of Molecular Biology (IMB) in Mainz since 2019, affiliated with Johannes Gutenberg University. His research focuses on transposable elements and their impact on mammalian genome regulation during development and evolution. His laboratory investigates how transposon biology influences genome stability through epigenetic mechanisms, particularly DNA methylation in germ cells and pluripotent stem cells. Key research areas include: piRNA-guided DNA methylation pathways involving DNMT3C Evolutionary arms races between transposons and host defense mechanisms Intergenerational transmission of epigenetic information Transposon-driven phenotypic variation (e.g., Agouti epiallele) Recent publications reveal a strong emphasis on epigenetic control of transposons in germline development, with significant contributions to understanding DNMT3 enzymes and their role in genomic stability. His work bridges molecular genetics, evolutionary biology, and epigenetics using mouse models and advanced genomic techniques. Dr. Barau mentors a multicultural research team with emphasis on scientific passion and career development, actively seeking motivated researchers for projects in transposon biology and epigenetic inheritance.

René Kettingمشاهده پروفایل

استاد

• RNA Biology
• Epigenetics
• Developmental Biology
• +۴ مورد دیگر

René Ketting is a Professor at the Faculty of Biology, Johannes Gutenberg University Mainz (JGU), and Scientific Director at the Institute of Molecular Biology (IMB), Mainz. His research focuses on small RNA-driven gene regulatory mechanisms in the germline, particularly piRNAs and their role in controlling transposable elements and epigenetic inheritance.

Jan Padekenمشاهده پروفایل

پژوهشگر

• Epigenetics
• Chromatin Biology
• Genome Stability
• +۶ مورد دیگر

Jan Padeken is a Group Leader at the Institute of Molecular Biology (IMB) in Mainz since 2022. His research focuses on epigenetic regulation through histone H3 lysine 9 methylation (H3K9me), exploring its roles in heterochromatin establishment, genome stability, and tissue integrity. Education: PhD in Cell Biology, Max Planck Institute of Immunobiology and Epigenetics, Freiburg (2013) Diploma in Biology, Albert-Ludwigs University, Freiburg (2009) Vordiploma in Biology, RWTH Aachen University (2006) His work investigates how persistent genotoxic stress alters heterochromatin dynamics in C. elegans , linking these changes to cancer, ageing, and Cockayne syndrome. He employs genetic tools, sequencing, and quantitative microscopy to analyze acute and long-term epigenetic responses. Recent research trends highlight his focus on: Pathways controlling H3K9 methylation Transposable element silencing Epigenetic stress adaptation Heterochromatin propagation

Özgen Denizمشاهده پروفایل

مدرس ارشد

• Transposable Elements
• Epigenetics
• Cancer Biology
• +۷ مورد دیگر

Dr Özgen Deniz is a Senior Lecturer and Group Leader at the Queen Mary University of London , Centre for Epigenetics. Her research focuses on the epigenetic regulation of transposable elements (TEs) and their role in blood cancers, particularly acute myeloid leukaemia (AML). She combines functional and computational genomics to investigate how TEs contribute to oncogenesis and cancer treatment efficacy. Core member of QMUL Epigenetics Hub Member of LMS Imperial TE Hub Member of European Haematology Association Theme Lead in Mobile DNA Editorial Board Her lab has uncovered TEs as novel oncogenic regulators in AML, demonstrating their ability to dysregulate gene expression and trigger anti-tumour immunity. Current projects include functional interrogation of TEs in adult and paediatric AML, supported by major grants such as the ERC Starting Grant (2024-2029) and Cancer Research UK Career Development Fellowship (2022-2028). Scientific Awards: Cancer Research UK Career Development Fellowship The Deniz Lab actively recruits researchers interested in transposon biology and cancer epigenetics, with collaborations across epigenetics and haematology networks. Their work bridges genomic instability, chromatin dynamics, and therapeutic resistance in leukaemia.

• Pathology
• Genetics
• Epigenetics
• +۴ مورد دیگر

Emma Helena Siili serves as a University Instructor in the Department of Pathology at the University of Helsinki, with clinical integration at Helsinki University Hospital (HUS). Her dual academic-hospital role positions her at the intersection of diagnostic pathology and translational research. Her research program investigates molecular underpinnings of gynecological diseases through three interconnected pillars: Genetic/epigenetic drivers of uterine leiomyomas (FGFR alterations, chromatin dynamics) Human retrotransposon biology in somatic and germline contexts Population genomics applications via the FinnGen biobank This work employs integrated genomic approaches to decode mechanisms in benign tumors with cancer relevance. Recent publications reveal a strong emphasis on collaborative, data-intensive studies leveraging Finland's national biobank resources. Dr. Siili's 2025 output demonstrates consistent high-impact contributions across pathology and genomics domains, with trends showing increasing focus on computational analysis of large-scale genomic datasets. Her publications consistently address women's health issues through molecular pathology lenses, bridging basic science and clinical applications. As a teaching-focused faculty member, she contributes to medical education while maintaining active research through departmental collaborations. Her work environment centers on the Department of Pathology's interdisciplinary teams, utilizing shared genomics infrastructure and HUS clinical resources to advance understanding of gynecological disease mechanisms.

• Computational biology
• Computational systems biology
• Biomedicine
• +۷ مورد دیگر

Dr. Kimmo Palin is a Medicum University Researcher and Docent at the University of Helsinki's Faculty of Medicine, where he serves as the Applied Tumor Genomics (ATG) Supervisor for both the Doctoral Programme in Integrative Life Science and the Doctoral Programme in Biomedicine. His research spans computational biology, tumor genomics, and cancer genetics, with particular focus on colorectal cancer, uterine leiomyomas, and the molecular mechanisms underlying cancer development. Dr. Palin integrates computational approaches with molecular and clinical data to investigate genetic and epigenetic alterations in tumors. Dr. Palin's recent publication record demonstrates significant contributions to cancer genomics, with multiple high-impact publications in 2024-2025 covering topics such as FGFR gene activation in uterine tumors, metabolomic characterization of colorectal cancer, retrotransposition events in human genomes, and large-scale genetic analyses identifying cancer susceptibility genes. He is actively involved in major research initiatives including the Centre of Excellence in Tumor Genetics Research (COETG) and the iCAN digital precision cancer medicine program, which provide substantial funding and collaborative opportunities for his research group. As a Docent and doctoral program supervisor, Dr. Palin plays a key role in training the next generation of cancer researchers, guiding students through doctoral studies with a focus on tumor genomics and computational approaches to cancer research.

• Chromatin Organization
• Epigenetics
• Plant Reproduction
• +۴ مورد دیگر

Dr. Célia Baroux is a Professor and Group Leader in the Department of Plant Developmental Genetics at the Institute of Plant Biology, University of Zurich. Her research program investigates the functional dynamics of chromatin organization in plant reproductive development, with significant contributions to understanding nuclear architecture and epigenetic regulation. Her primary research interests focus on: 3D genome organization in epigenetic regulation Chromatin dynamics during cell fate specification Nuclear envelope interactions in plant cells Reproductive development in Arabidopsis Evolutionary aspects of epigenetic mechanisms Analysis of her recent publications (2020-2022) reveals a consistent focus on chromatin architecture, with particular emphasis on histone modifications, nuclear positioning, and transposable element regulation. Her work bridges molecular genetics, epigenomics, and developmental biology, often employing innovative technical approaches like inducible gene systems in ovules. Dr. Baroux actively contributes to the scientific community through editorial roles at Frontiers in Plant Science and co-founding the INDEPTH Academy, which serves as a collaborative platform for researchers studying nuclear domains in plants. Her extensive publication record demonstrates consistent productivity in high-impact plant science journals. Her laboratory maintains an active research program with international collaborations, as evidenced by multi-institutional publications spanning Switzerland, France, the UK, and beyond. The lab's work combines molecular genetics, advanced imaging, and computational approaches to unravel fundamental mechanisms of plant reproduction.

Jeremy Lubanمشاهده پروفایل

استاد

• Virology
• Molecular Biology
• Infectious Diseases
• +۴ مورد دیگر

Jeremy Luban is the David J. Freelander Chair in AIDS Research at the University of Massachusetts Medical School, with joint appointments at the Broad Institute of MIT and Harvard, Ragon Institute of MGH, MIT and Harvard, and Massachusetts Consortium on Pathogen Readiness. He holds an M.D. from Columbia University College of Physicians and Surgeons and a B.A. in Biology and Music from SUNY Purchase. His research focuses on virology, molecular mechanisms of infectious diseases (particularly HIV/AIDS and emerging viruses), host-pathogen interactions, and genomic approaches to disease mechanisms. Work spans viral pathogenesis, retrovirology, and host defense systems, with emphasis on structural biology of viral components and therapeutic interventions. Recent publications demonstrate extensive work in viral evolution, host immune responses to pathogens like HIV, Ebola, and SARS-CoV-2, and innovative gene-editing technologies. Research consistently integrates molecular virology with computational and structural approaches to address fundamental questions in infectious disease biology. Awards/Honors: David J. Freelander Chair in AIDS Research

Emile Gluck-Thalerمشاهده پروفایل

استادیار

• Fungal Pathology
• Plant Pathology
• Horizontal Gene Transfer
• +۴ مورد دیگر

Emile Gluck-Thaler is an Assistant Professor in the Department of Plant Pathology at the University of Wisconsin-Madison, affiliated with the College of Agricultural and Life Sciences. His research focuses on fungal genetics, horizontal gene transfer, and genome evolution, particularly in plant pathogens. Education: PhD in Plant Pathology, The Ohio State University BS in Life Sciences with Microbiology Specialization, McGill University, Canada Research Interests span fungal genomics, transposable elements, and mechanisms of pathogen adaptation. He investigates how mobile genetic elements drive diversity and resistance in plant pathogens like Macrophomina phaseolina and Pyricularia species. Notable Trends in Research include the role of giant transposons in horizontal gene transfer, geostatistical modeling for pathogen distribution, and the evolutionary implications of metabolic gene clusters in fungi. Labs & Collaborations: He works in the Discovery Building at UW-Madison, contributing to interdisciplinary research on fungal biology and plant-microbe interactions.

Biswajyoti Sahuمشاهده پروفایل

پژوهشگر ارشد

• Biomedical Sciences
• Cancer Biology
• Transcriptional Regulation
• +۳ مورد دیگر

Biswajyoti Sahu is an Academy Research Fellow and Docent at the University of Helsinki, affiliated with the Doctoral Programme in Integrative Life Science and the Applied Tumor Genomics (ATG) group at Medicum. He previously served as a Visiting Scientist at the University of Cambridge (2018–2019) and the Whitehead Institute for Biomedical Research (2015). Biomedical Sciences Cancer Biology Transcriptional Regulation Epigenetics His research focuses on oncogenes, transcription factor dynamics, and epigenetic mechanisms in cancer and development. Key themes include chromatin modifier enzymes, transposable elements, and cellular reprogramming. Recent publications highlight his work on oncogene convergence pathways (2025), transposable element derepression (2025), and single-cell multiome protocols (2024). Awards include the Finnish Cultural Foundation’s Grant (2011), Endocrine Trainee Day Fellowship (2009), and multiple presentation awards.

• Plant Molecular Biology
• Genetics
• Epigenetics
• +۶ مورد دیگر

Dr. Chris Winefield is an Associate Professor in the Department of Wine Food & Molecular Biosciences at Lincoln University's Faculty of Agriculture and Life Sciences in New Zealand. His research focuses on plant molecular biology and genetics, particularly studying transposable elements in crop evolution and epigenetic regulation in response to changing environments. He works extensively with horticultural plant species such as grapevine and hops, investigating key industry issues including seasonal variation in flowering, fruit and flower development, and the development of flavor and aroma biochemistry. Dr. Winefield earned his PhD from the University of Otago and his MSc (Hons) from Waikato University. His academic career includes positions as Senior Lecturer at Lincoln University (2004-2021), Post Doctoral Fellow at the University of York (2001-2004), and Scientist at Crop & Food Research Ltd (1994-2001). His research program utilizes diverse methodologies including de-novo genome sequencing and annotation, whole genome bisulphite sequencing, traditional breeding/genetics, and agronomic assessment of grape and hop populations. A key focus is studying how controlled bursts of transposon activity can be used to develop new germplasm to meet industry challenges. His work addresses significant issues related to climate change, food security, and sustainable agricultural practices, aligning with UN Sustainable Development Goals including Zero Hunger, Quality Education, Responsible Consumption and Production, Climate Action, and Life on Land. Dr. Winefield's publication record demonstrates consistent contributions to plant genomics, epigenetics, and viticulture research. His recent work shows increasing focus on transposable elements, genome regulation, and the molecular basis of traits important to horticultural industries. He has developed expertise in both long-read and short-read sequencing technologies and their application to plant genome analysis. Chairperson Bio-safety committee (2012-present) Member Faculty Agriculture and Life Sciences research committee (2018-present) Dr. Winefield actively supervises postgraduate students, with numerous completed Masters and PhD projects focusing on various aspects of plant genetics, molecular biology, and horticultural science. His laboratory continues to develop innovative approaches to studying plant genome dynamics and their applications to crop improvement.

Simon Chong Chuمشاهده پروفایل

پژوهشگر ارشد

• Computational Biology
• Genomics
• Transposable Elements
• +۳ مورد دیگر

Simon Chong Chu, Ph.D. serves as a Caspar Wistar Fellow in the Molecular and Cellular Oncogenesis Program at The Wistar Institute. A computational biologist specializing in genomic repeats research, Chu develops innovative computational methods to investigate transposable elements and their critical roles in human health and disease. Chu's research interests focus on genomic repeats—including transposable elements (TEs), short and long tandem repeats, and large satellite repeats—that constitute over half of the human genome. His work integrates systems biology with cutting-edge genomics to uncover how these elements influence development, evolution, and disease processes. He has developed computational tools like xTea, REPdenovo, GINDEL, SpliceJumper, GAPPadder, and TrapHunter that have been widely adopted across diverse research contexts. Chu's publication record demonstrates expertise in both cancer genomics and computational methodology development. His recent work examines retroelement contributions to birth defects and childhood cancers, the landscape of human SVA retrotransposons, and comprehensive identification of transposable element insertions using multiple sequencing technologies. His research bridges computational innovation with biological discovery, particularly in understanding how genomic repeats evade suppression mechanisms and contribute to disease states. Chu earned his Ph.D. in Computer Science and Engineering from the University of Connecticut and completed postdoctoral training in the Department of Biomedical Informatics at Harvard Medical School. Prior to joining The Wistar Institute in 2025, he worked as a principal scientist at ROME Therapeutics, where he contributed to clinical drug discovery.

• Plant Genetics
• Meiosis
• Recombination
• +۵ مورد دیگر

Dr. Ian Henderson is a Reader (equivalent to Associate Professor) in Plant Sciences at the University of Cambridge, where he has maintained an active research program since 2008. His work focuses on fundamental mechanisms of plant genome organization, transmission, and evolution. His research interests span several interconnected areas: Meiotic recombination mechanisms in plants Centromere structure, function, and evolution Epigenetic regulation of genome stability Transposable element dynamics and impact on genome architecture Chromatin organization in plant genomes Dr. Henderson's laboratory employs Arabidopsis thaliana as a primary model system but extends findings to other plant species including maize and wheat. His research has revealed critical insights into how chromatin structure influences crossover formation during meiosis, the evolutionary dynamics of centromeres across plant species, and the role of epigenetic modifications in regulating genome stability. Recent work has utilized advanced genomic technologies including CRISPR-based approaches, long-read sequencing for complex genomic regions, and sophisticated computational analysis. His publication record demonstrates consistent high-impact research output, with numerous papers in top-tier journals including Nature Communications, PNAS, and Nature Plants. His work shows an increasing trajectory of research impact, with multiple significant publications appearing in 2025. The research often involves international collaborations across Europe and North America. Dr. Henderson's lab provides training opportunities for graduate students and postdoctoral researchers interested in plant genomics, meiosis, and epigenetics. Students in his laboratory develop expertise in molecular genetics, genomic analysis, and computational approaches to complex biological problems. The research has implications for both fundamental biological understanding and potential applications in plant breeding and agricultural biotechnology.