جست‌وجوی استاد و پژوهشگر

Liliana Mancio Silvaمشاهده پروفایل

پژوهشگر

• Host-pathogen interactions
• Malaria
• Parasitology
• +۷ مورد دیگر

Liliana Mancio Silva is a researcher at the Institut Pasteur in Paris, France, where she leads projects focused on malaria pathogenesis and drug discovery. She is the Principal Investigator of the PANDORA project, which aims to identify drugs effective against all stages of malaria using data from the COSIPOP cohort. Her research leverages advanced bioengineered human liver systems and single-cell technologies to study host-pathogen interactions, particularly in Plasmodium vivax and Plasmodium falciparum infections. Her research interests include host-pathogen interactions, metabolism in infectious disease, parasite dormancy (hypnozoites), single-cell analysis, and drug repurposing. She investigates how malaria parasites manipulate host hepatocyte metabolism and how circadian rhythms influence drug responses. Her work bridges molecular parasitology, systems biology, and translational medicine. The recent publications highlight a strong trend in single-cell and transcriptomic analysis of Plasmodium infection, the development of humanized liver models, and the exploration of host metabolic pathways as therapeutic targets. Her work spans from basic mechanisms of parasite biology to applied drug discovery. Scientific Awards: Liliana Mancio Silva advises several PhD students and postdoctoral researchers and is involved in collaborative drug discovery initiatives at the Institut Pasteur. She has no listed formal education in the provided text, but her publication record suggests a strong background in molecular parasitology and cell biology. She is actively involved in the development and application of bioengineered liver platforms (microlivers) for studying hepatotropic pathogens such as malaria parasites and hepatitis viruses.

Marc Monotمشاهده پروفایل

پژوهشگر

• Genomics
• Transcriptomics
• Bioinformatics
• +۷ مورد دیگر

Marc Monot is a researcher and platform manager at the Biomics platform within the Institut Pasteur, a leading institution in microbiology and infectious diseases. He plays a central role in managing next-generation sequencing (NGS) technologies and bioinformatics resources, supporting both internal and external research teams. His work bridges technological infrastructure and scientific discovery, particularly in microbial genomics and host-pathogen interactions. His research interests span genomics, transcriptomics, bioinformatics, phage biology, Clostridioides difficile pathogenesis, single-cell analysis, and microbial biofilms . He applies high-throughput sequencing and computational tools to understand bacterial virulence, adaptation, and gene regulation. His work often involves developing and applying bioinformatics pipelines for NGS data analysis. The recent publications highlight a strong focus on microbial genomics and host-pathogen dynamics. Key themes include pathogen evolution (e.g., Listeria, Candida, C. difficile), phage biology, biofilm formation, and vaccine development . The use of advanced techniques like single-cell transcriptomics and long-read sequencing (e.g., Oxford Nanopore) is evident, reflecting a commitment to cutting-edge methodologies. His work bridges fundamental biology with potential clinical and public health applications. Marc Monot has led and contributed to significant research projects such as CDPhages – ANR JCJC and the Single Cell Transcriptomics, Epigenetics and Genomics initiative. He has also developed key bioinformatics tools like PhageTerm and COV2HTML , demonstrating expertise in both wet-lab and computational biology. He has been actively involved in training and education, organizing and teaching workshops on bacterial RNAseq and NGS data analysis, contributing to capacity building in genomics both at Institut Pasteur and internationally (e.g., in Tunis). His collaborations span multiple teams and international partners, reflecting an integrative and collaborative research approach.

Nadia Naffakhمشاهده پروفایل

پژوهشگر

• Virology
• Influenza virus
• RNA synthesis and processing
• +۷ مورد دیگر

Nadia Naffakh is a permanent researcher at the Institut Pasteur in Paris, affiliated with the Stroma, inflammation and tissue repair group within the Department of Biochemistry and Chemobiology. She leads multiple research projects focused on influenza virus molecular biology, including viral RNA trafficking, transcription mechanisms, and host-pathogen interactions. Her work is highly collaborative, involving partnerships with institutions such as EMBL Grenoble and CSIC Madrid. University: Institut Pasteur School: Stroma, inflammation and tissue repair Department: Biochemistry and Chemobiology Position: Researcher Email: nadia.naffakh@pasteur.fr Her research focuses on the molecular mechanisms of influenza virus replication, particularly how the virus hijacks host cellular machinery such as RNA polymerase II. She also investigates host factors influencing viral susceptibility across populations, including differences in monocyte responses between individuals of African and European ancestry. Her lab employs cutting-edge techniques such as engineered tagged viruses and high-throughput screening assays. The recent publications (2018–2024) reflect a strong emphasis on viral transcription, RNA processing, host interactions, and antiviral strategies, including work on SARS-CoV-2. Topics span from basic virology to drug discovery, indicating a broad and impactful research program. Scientific Contributions: Elucidated the role of host RNA polymerase II CTD in influenza genome replication. Developed sensitive luciferase assays for antiviral screening. Demonstrated population-level differences in innate immune responses to influenza. Explored host splicing machinery as a target for anti-influenza therapy. Nadia Naffakh mentors several PhD students and postdoctoral researchers and is actively involved in the Chemogenomic and Biological Screening Platform (PF-CCB) and the ATC-DDS initiative at the Institut Pasteur. She has not received any explicitly mentioned scientific awards in the provided texts, but her publication record in high-impact journals underscores her scientific leadership. Her laboratory contributes significantly to understanding viral pathogenesis and developing novel therapeutic approaches.

Lluis Quintana-Murciمشاهده پروفایل

استاد

• Human Evolutionary Genetics
• Population Genetics
• Genomics
• +۳ مورد دیگر

Lluis Quintana-Murci is a Professor at Collège de France and leads the Human Evolutionary Genetics team at Institut Pasteur. His work bridges evolutionary biology, genomics, and immunology, focusing on how genetic and environmental factors shape human immune variation. Key projects include Milieu Intérieur (genetics-environment-immunity interplay) and studies on natural selection footprints in the human genome. 2019: Appointed Professor at Collège de France Awards: Allianz-Institut de France Prize (2019), Prix Duquesne (2019) Research spans: Human adaptation to pathogens and environmental stressors Evolutionary genomics of innate/adaptive immunity Ancient DNA analysis for tracking immune evolution Steroid hormone genetic regulation Epigenetic aging mechanisms in African populations His recent publications highlight genetic epidemiology of SARS-CoV-2 responses, cytokine autoantibody impacts, and transposable element roles in protein isoform diversity. Collaborations include LabEx Milieu Intérieur and ERC-funded projects on human evolutionary immunogenomics. Scientific awards: Allianz-Institut de France Prize (2019) Prix Duquesne (2019)

• Microbiology
• Parasitology
• Environmental Science
• +۴ مورد دیگر

Nicolas BLOT is a Lecturer (HDR) at the Université Clermont Auvergne's Faculty of Biology. His primary affiliation is with the UMR CNRS/UCA laboratory focusing on microorganisms and environmental genomics. He also serves as a Guest Researcher at the Plant Protection Center (UMR Cirad/U.Réunion) in Saint-Pierre, Réunion, studying plant pests and tropical ecosystems. Research interests include bee health, interactions between stress factors (e.g., Varroa, Nosema, pesticides), and their impacts on bee populations. His work encompasses epidemiological surveillance, genetics of parasite populations, and bee response mechanisms (transcriptomics, microbiota, behavior). Previous research involved Blastocystis hominis organelles, marine cyanobacteria physiology, DNA-protein interactions, and plant pathogen virulence. Teaching responsibilities include microbiology, cellular/molecular biology, and biochemistry at undergraduate and graduate levels at the Faculty of Biology. He also contributes to continuing education for science teachers in Auvergne. Affiliations include the Cézeaux University Campus (Aubière, France) and the Saint-Pierre Plant Protection Center. No academic awards or grants are explicitly mentioned in the provided texts.

• Antibiotic resistance
• Biofilm research
• Microbial genetics
• +۳ مورد دیگر

Nicolas CHARBONNEL is a permanent research staff member at the Laboratoire Microorganismes : Génome et Environnement (LMGE) at Université Clermont Auvergne, where he conducts research on bacterial pathogenesis, antibiotic resistance, and biofilm formation mechanisms. His work is primarily focused on Klebsiella pneumoniae and other pathogenic bacteria. His research interests center around understanding the molecular mechanisms of biofilm formation and developing novel strategies to combat antibiotic-resistant bacteria. CHARBONNEL's work spans from fundamental studies of bacterial communication and gene regulation to applied research on antimicrobial compounds and CRISPR-Cas9 based resensitization approaches. He has made significant contributions to understanding how bacteria develop resistance within biofilm communities and how to overcome these defenses. Analysis of his recent publications reveals a strong focus on developing novel antimicrobial compounds, particularly peptoid-based molecules that mimic natural antimicrobial peptides. His work also demonstrates increasing application of CRISPR-Cas9 technology to target antibiotic resistance genes directly within bacterial communities. A consistent theme across his research is the investigation of Klebsiella pneumoniae biofilm formation mechanisms and vulnerabilities. CHARBONNEL collaborates extensively with Christiane Forestier and other researchers at LMGE, as well as with clinical researchers studying hospital-acquired infections. His research bridges fundamental microbiology with practical applications for combating antibiotic-resistant infections.

• Bioinformatics
• Genomics
• Microbial Ecology
• +۳ مورد دیگر

Damien COURTINE is a Staff Scientist and Bioinformatician at the Microorganisms: Genome and Environment Laboratory (LMGE) at Clermont Auvergne University, where he has held a permanent position since December 2021. His work spans two research teams (MEB and IHP), focusing on bioinformatics analysis of microbial communities and genome analysis. Dr. COURTINE earned his PhD in Microbiology from the University of Western Brittany (2017), an MSc in Bioinformatics from Blaise Pascal University (2014), a BSc in Biology (2012), and a Technical Diploma in Biology laboratory technician work (2011). Prior to his current position, he was a Post-doctoral Fellow at the Center d'Immunologie de Marseille-Luminy (2019-2021). His research interests include bioinformatics, genomics, microbial ecology, metagenomics, and comparative genomics. Dr. COURTINE specializes in analyzing high-throughput sequencing data from microbial communities, developing genome analysis tools, and providing technical support related to sequencing methods. He works extensively with metagenomic, metatranscriptomic, and metabarcoding approaches, particularly focused on lake microorganism communities in Lake Pavin. Dr. COURTINE's publication record demonstrates expertise in microbial ecology, particularly in extremophiles, microbial eukaryotes, and bacterial communities in meromictic lakes. His work often involves comparative genomics of archaea (particularly Thermococcales), metagenomic analysis of freshwater ecosystems, and development of bioinformatics tools. Recent publications span from 2021-2025, showing consistent productivity across multiple high-impact journals. Since 2024, Dr. COURTINE has been teaching in the bioinformatics master's course at the University of Clermont Auvergne, where he instructs students in algorithms for short-read alignments using Python and the Burrow-Wheeler transform method. His technical expertise includes Linux, high-performance computing (SLURM), version control with git, SnakeMake pipelines, Docker/Singularity containers, and programming in Python, R, and BASH.

• Microbiology
• Parasitology
• Microsporidia Research
• +۴ مورد دیگر

Dr. Frederic Delbac is a researcher at Clermont Auvergne University, affiliated with the Faculty of Biology and the Laboratoire Microorganismes : Génome et Environnement (LMGE), which operates under the auspices of the Centre National de la Recherche Scientifique (CNRS). With a prolific publication record spanning over two decades, Dr. Delbac has established himself as a leading expert in microsporidian biology and honeybee pathology. His research bridges fundamental microbiology with practical applications in apiculture and environmental health. Dr. Delbac's primary research focus centers on microsporidia, obligate intracellular parasites that infect diverse hosts including honeybees. His work on Nosema ceranae has significantly advanced understanding of how this pathogen affects honeybee physiology, particularly lipid metabolism in the fat body. He has also conducted extensive research on Blastocystis, another protist parasite with implications for human and animal health. His methodological approach integrates genomic, transcriptomic, and molecular techniques to elucidate parasite biology, evolutionary relationships, and host-pathogen interactions. Dr. Delbac's research frequently addresses critical questions in pollinator health, contributing to solutions for honeybee colony losses worldwide. Analysis of Dr. Delbac's publication trajectory from 2019-2025 reveals evolving research priorities with consistent themes. Early work focused on fundamental aspects of microsporidian biology, particularly the polar tube structure and invasion mechanisms, as evidenced by his 2008 and 2014 book chapters. More recent publications demonstrate a shift toward applied research addressing honeybee health crises, including probiotic strategies against foulbrood, the impact of Nosema ceranae on lipid reserves, and microbiome dysbiosis in pesticide-parasite co-exposures. His 2024-2025 publications indicate growing interest in bioinformatics approaches to microsporidian genomics and paleogenomic studies of microsporidian evolution in environmental contexts. Dr. Delbac maintains active collaborations across multiple institutions, including international partnerships with researchers in Ireland and the United Kingdom. His work has practical implications for apiculture, environmental monitoring, and understanding host-parasite coevolution. As evidenced by his ongoing research projects and recent publications, Dr. Delbac continues to make significant contributions to parasitology and environmental microbiology.

• Genomics
• Microbiology
• Bioinformatics
• +۳ مورد دیگر

Valerie Polonais is a Researcher affiliated with the IUT Clermont Auvergne at Université Clermont Auvergne . Her research focuses on microbial genomics, particularly the study of microsporidian pathogens, with emphasis on genome annotation workflows, protein localization, and comparative genomics. She has contributed to understanding the genetic mechanisms of these obligate intracellular parasites through analysis of model organisms like Drosophila melanogaster. Key research themes include: Microbial genome sequencing and annotation Host-pathogen interactions at molecular level Evolutionary genomics of minimal eukaryotic organisms Development of bioinformatics tools for genomic analysis Her work bridges fundamental microbiology with computational approaches, addressing both basic science questions and potential applications in infectious disease research. Recent studies emphasize functional characterization of polar tube proteins and genomic features of parasitic microbes.

Gabriel Peyréمشاهده پروفایل

استاد پژوهشی

• Optimal Transport
• Machine Learning
• Data Science
• +۴ مورد دیگر

Gabriel Peyré is a CNRS Research Professor at the Department of Mathematics and Applications (DMA) of École normale supérieure (ENS) in Paris, France. A specialist in data science and artificial intelligence, he is renowned for his work on optimal transportation theory and its applications to imaging, machine learning, and neural network training. His research bridges mathematical theory with computational algorithm design, earning him the CNRS Silver Medal (2021) and multiple European Research Council (ERC) grants, including the 2024 Advanced Grant. Research interests include: Optimal Transport Machine Learning AI Theory Image Processing Computational Mathematics Neural Network Training His recent publications focus on advancing optimal transport methods in AI, with applications in neural network learning, spatial transcriptomics, and unsupervised data analysis. He has developed algorithms for large-scale optimal transport computations and contributed to theoretical understanding of transformer models and residual networks. Scientific awards: CNRS Silver Medal (2021) ERC Advanced Grant (2024) ERC Consolidator Grant (2016) ERC Starting Grant (2011) Blaise-Pascal Prize from the Academy of Sciences (2017) He supervises PhD students and postdoctoral researchers, including Raphaël Barboni, Valérie Castin, and Geert-Jan Huizing. His work involves collaborations with institutions like INRIA, MIT, and Heriot-Watt University. Peyré's affiliations include the Center for Data Sciences at ENS, where he contributes to interdisciplinary projects in biology and physics.

Chen Yiranمشاهده پروفایل

استاد

• Mass Spectrometry
• Proteomics
• Peptidomics
• +۷ مورد دیگر

Chen Yiran is a Researcher at the Agricultural Biotechnology Research Center, Academia Sinica , where he has contributed to mass spectrometry , proteomics , and plant immunity . He serves as Chairman of the Taiwan Mass Spectrometry Society and holds Professor positions at National Chung Hsing University (Center for Biotechnology Development), National Taiwan University (Institute of Biotechnology/Systems Biology Program), and National Taiwan Ocean University (Department of Life Science and Biotechnology). His work spans peptidomics , DNA adductomics , and plant-microbe interactions . Chen's research integrates mass spectrometry with bioinformatics to study environmental health risks, plant immune signaling, and disease mechanisms. His team has developed tools like the FeatureHunter software for adduct detection and UniQua signal processor for proteomics. Current projects include CAPE9 peptide characterization for plant immunity and oxidative stress analysis in metabolic disorders. 2025: Outstanding Talent Development Foundation Leap Lecture 2024: Taiwan Mass Spectrometry Society Outstanding Scholar Award 2016: Academia Sinica Young Scholars Research Book Award 2015: Yang Xiangfa Agricultural Sciences Young Scholar Award Laboratory members include doctoral students Ying Guangting , Anciotti , and Jiefan . The lab operates at Academia Sinica's Agricultural Science Building A523 , with equipment for advanced chromatography-mass spectrometry and proteome analysis . Collaborations span National Taiwan University , Stanford , and UC Davis alumni networks.

Vincent Rouillyمشاهده پروفایل

پژوهشگر

• Immunology
• Infectious Diseases
• Systems Biology
• +۳ مورد دیگر

Vincent Rouilly is a researcher at Institut Pasteur , Paris, specializing in systems immunology and infectious disease diagnostics. He is a key member of the Milieu Intérieur Consortium , focusing on standardized immunomonitoring techniques and host-pathogen interactions. Current projects analyze TLR4-IFNβ-IL-12p70 signaling in tuberculosis and SARS-CoV-2 infections Led development of next-generation diagnostic tools like TruCulture assays His research spans: Immunology : Innate/adaptive immunity, cytokine networks Infectious Diseases : Tuberculosis, SARS-CoV-2, Mycobacterium tuberculosis Systems Biology : Transcriptional profiling, nCounter assays Microbiota : Diet-gut-immune axis Inflammatory Disorders : TNF-blocker mechanisms in spondyloarthritis From 2015–2022, his publications demonstrate expertise in standardized whole blood stimulation, digital ELISA integration, and multi-center immunomonitoring. Collaborations include teams studying HIV-1, Aspergillus, and antibiotic resistance.

Marie-Laure Delignette-Mullerمشاهده پروفایل

پژوهشگر

• Biostatistics
• Ecotoxicology
• Microbial Risk Assessment
• +۳ مورد دیگر

Marie-Laure Delignette-Muller is a teacher-researcher at the Veterinary Campus, specializing in biostatistics and ecotoxicology. She is affiliated with the Basic Sciences Teaching Department and the Biometrics and Evolutionary Biology Laboratory. Her ORCID is 0000-0001-5453-3994. Research Interests: Biostatistics, Bayesian inference, dose-response modeling, species sensitivity distributions, and microbial risk assessment. She has developed tools like DRomics and MOSAIC for ecological and toxicological data analysis. Publication Trends: Recent works focus on veterinary diagnostics (e.g., ELISA tests for C. burnetii), environmental toxicology (tire particles, triclosan), and microbial ecology (Wolbachia, STEC). Her articles integrate statistical modeling with biological applications. Teaching: Biostatistics, linear and mixed models, distribution fitting, and critical reading of scientific articles. Educational resources available at https://biostatistique.vetagro-sup.fr .

Antonin Tortereauمشاهده پروفایل

پژوهشگر

• Pathology
• Histology
• Oncology
• +۳ مورد دیگر

Antonin Tortereau serves as a Researcher at VetAgro Sup within the Veterinary School, holding dual affiliations with the Companion Animal Clinic, Leisure and Sport teaching department and the UR ICE (Cell Environment Interactions) research unit. His work is clinically supported by the Veterinary University Hospital (CHUV) companion animal facilities, where he conducts translational research bridging veterinary and human medicine. His research spans Pathology, Histology, Oncology, and Molecular Biology with specific focus on tumor suppressor mechanisms, metabolic disorders, and cell-environment interactions. Key investigations include netrin-1/DCC signaling in lymphomas, EDAR receptor function in melanoma, oral tumorigenesis pathways, and renal complications in glycogen storage diseases—demonstrating a consistent emphasis on molecular pathogenesis and therapeutic targeting across species. Publications from 2016-2018 reveal a cohesive research trajectory in cancer biology and metabolic disease, characterized by mechanistic studies using mouse models and human tissue analyses. His work frequently explores cell death pathways and receptor signaling, with direct implications for developing targeted interventions in both veterinary and human oncology contexts. No scientific awards are documented in the provided materials. Teaching responsibilities encompass Pathological anatomy and Histology instruction, though no student advisement details or grant funding information appear in the source text. He operates within the UR ICE research unit investigating cellular microenvironment dynamics and utilizes CHUV's companion animal hospital for clinical correlations, maintaining strong integration between basic science and veterinary clinical practice.

Françoise Lericheمشاهده پروفایل

پژوهشگر

• Food Microbiology
• Dairy Science
• Pathogen Control
• +۳ مورد دیگر

Françoise Leriche is a faculty member at VetAgro Sup's Agronomic Campus, serving in the Food Quality and Economics department. She is affiliated with the UMR-F (UMR on Cheese) research unit and contributes to technical platforms like the Food Characterization Laboratory (Biotic Fraction). Her work bridges teaching and research in microbiology. Research Keywords : Food Microbiology, Pathogen Control, Microbial Interactions, Dairy Science, Flow Cytometry, Food Safety. Françoise Leriche's research focuses on microbial behavior in food systems, particularly raw milk cheeses. Her work includes studying antimicrobial activity of essential oils, pathogen survival under gastrointestinal and environmental conditions, and microbial interactions in dairy products. She employs advanced techniques like flow cytometry and transcriptomics. Recent articles highlight her expertise in pathogen detection (E. coli, Salmonella, Pseudomonas), terroir-based agricultural development, and microbial safety of fermented foods. These studies span molecular biology, food processing, and environmental microbiology. Leriche serves as an expert for the French National Agency for Food, Environmental and Occupational Health & Safety (ANSES). She has led projects funded by BPI France, FEDER, Région Auvergne, and CPER/DGAL, focusing on foodborne pathogens and cheese quality. Her laboratory affiliations include the UMR-F research unit and Flow Cytometry platform at VetAgro Sup. She collaborates with institutions like Université Lyon 1, CNRS, and industry partners such as Lallemand and Pôle fromager AOP Massif central.