Synaptic Remodeling Professors and Supervisors | ApplySharif

جست‌وجوی استاد و پژوهشگر

استاد راهنما، استاد دانشگاه یا پژوهشگر مناسب برای مسیر پژوهشی‌تان را پیدا کنید و با او ارتباط بگیرید.

نمایش ۱-۱۵ از ۷۰۹ استاد راهنما

اطلاعات این پروفایل‌ها از صفحات عمومی دانشگاه‌ها جمع‌آوری شده و ممکن است به‌روز نباشد.

Brent Doironمشاهده پروفایل

استاد

University of ChicagoUnited States

Brent Doiron is a Professor at the University of Chicago, holding appointments in the Departments of Neurobiology and Statistics, and serving on the Committee on Computational and Applied Mathematics (CCAM). His research integrates nonlinear dynamics and statistical mechanics to study neural circuit variability, focusing on mechanisms underlying neural coding and network learning through collaborations with experimentalists in sensory systems. Education: PhD in Physics (University of Ottawa, 2004) Postdoc: Center for Neural Science at New York University (2017) Previous Roles: Mathematics Professor at University of Pittsburgh (2007-2020), Co-Director of Neural Computation Program at Carnegie Mellon Neuroscience Institute Research interests center on neuronal population dynamics, recurrent circuit mechanisms, and computational neuroscience. Current work investigates correlated variability in cortical networks, inter-areal communication, and stochastic spiking models. Recent publications emphasize cortical stability/gain modulation, asynchronous/synchronous activity balance, and Bayesian inference frameworks. Key themes include sensory processing, network plasticity, and dimensionality reduction in neural coding. Scientific Awards Alfred P. Sloan Research Fellowship in Neuroscience Vannevar Bush Faculty Fellowship Chancellor’s Distinguished Research Award (University of Pittsburgh) Active grants include NIH R01 and R90/T90 awards for neuronal dynamics research and computational neuroscience training programs.

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Jonny Kohlمشاهده پروفایل

پژوهشگر

Francis Crick InstituteUnited Kingdom

Jonny Kohl is a Group Leader at the Francis Crick Institute , where he established the State-dependent Neural Processing Laboratory in 2019. His work bridges neural circuits and internal physiological states (e.g., hunger, pregnancy) to decode instinctive behaviors like parenting and aggression in mice. PhD: MRC Laboratory of Molecular Biology, Cambridge (2013) Postdoc: Harvard University (2014–2019) with support from EMBO, HFSP, and Wellcome Trust fellowships Research Interests : Kohl investigates how hormonal and metabolic states dynamically rewire neural circuits to drive adaptive behaviors. His lab combines circuit neuroscience , molecular biology , and behavioral profiling to study: State-dependent neural processing in parental behavior Chemosensory dominance hierarchies in mice Plasticity mechanisms in aggression circuits Development of ultrafast tissue labeling and cryoanesthesia tools Scientific Trends : His recent publications highlight hormone-mediated synaptic remodeling (2023), cost-effective lab tools (2023), and brain-wide activity mapping (2016). Collaborative work spans computational biology , metabolism , and imaging disciplines. Honors: NARSAD Young Investigator Award (2019), ERC Starting Grant (2019), Wellcome Trust Discovery Award (2025) Grants: BBSRC Research Grant (2025), BBSRC Pioneer Grant (2023) His lab mentors PhD and MSc students and has developed open-source neuroscience tools (e.g., cryoanesthesia device, 2023). Kohl's research has been featured in Nature , Science , and Cell .

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Vilhelm Bohrمشاهده پروفایل

عضو هیئت علمی

University of CopenhagenDenmark

Vilhelm Bohr is an Affiliate Professor at the Department of Cellular and Molecular Medicine , University of Copenhagen, affiliated with the Molecular Aging Program and Center for Healthy Aging . His research explores the interplay between DNA maintenance , mitochondrial biology , and aging , particularly in age-associated neurodegeneration and Alzheimer’s disease. Research Interests include: Molecular mechanisms linking NAD + metabolism to mitochondrial dysfunction and neurodegeneration Role of tau pathology in DNA damage and mitochondrial stress Impact of Aprataxin (APTX) and RECQL4 helicase defects on mitochondrial DNA integrity Pharmacological strategies to improve mitochondrial health via autophagy modulation Publications (2025-2024) span topics like NAD + biosynthesis, Werner/Rothmund-Thomson syndromes, tau nuclear functions, and mitochondrial turnover, with high citations and media attention. Collaborations extend to clinical tumor samples and CRISPR-based disease models.

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Suradip Dasمشاهده پروفایل

استادیار

University of PennsylvaniaUnited States

Suradip Das is a Research Assistant Professor in the Department of Neurosurgery at the Perelman School of Medicine, University of Pennsylvania, where he serves as a Senior Research Investigator. His work bridges neural engineering and regenerative medicine to address critical challenges in nerve and muscle repair. His academic training includes: B.Tech in Biotechnology from Heritage Institute of Technology (2010) PhD in Biosciences and Bioengineering from Indian Institute of Technology Guwahati (2016) Dr. Das specializes in biomaterials development , peripheral nerve injury models , neuromuscular interface engineering , and stem cell-based regeneration . His research pioneers innervated tissue-engineered muscle constructs, demonstrating how motor neurons and endothelial cells synergistically enhance skeletal myocyte maturation. He innovates custom mechanobioreactors that apply tensile forces to guide nanofiber alignment for optimal myofiber formation, significantly advancing volumetric muscle loss treatments. Analysis of his 15 most recent publications reveals a dominant focus on neuromuscular regeneration (75% of articles), with emerging exploration of psychedelic compounds in neural repair. His work consistently integrates human iPSC-derived models , multi-cellular co-cultures , and large-animal validation to address translational gaps. Key trends include optogenetic control of motor units (2023), porcine nerve injury models (2020), and the critical role of pre-innervation in creating pro-regenerative microenvironments (2020-2022). As a core member of the Cullen Lab, Dr. Das collaborates on developing biofabricated neural microtissues for delayed nerve fusion and rapid functional recovery. His research directly informs clinical strategies for peripheral nerve repair and muscle regeneration through rigorous mechanistic studies and innovative engineering solutions.

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Matthew W. Buczynskiمشاهده پروفایل

استادیار

Virginia Polytechnic Institute and State UniversityUnited States

Matthew W. Buczynski is an Assistant Professor at the School of Neuroscience , part of the College of Science at Virginia Tech . Holding a Ph.D. in Biochemistry from the University of California San Diego (2008) and postdoctoral training at The Scripps Research Institute (2009-2016), he joined Virginia Tech in August 2016 after completing his postdoctoral fellowship. Education: B.S. in Chemistry, University of Michigan , 2001 Ph.D. in Biochemistry, University of California San Diego , 2008 Postdoctoral Training, The Scripps Research Institute , 2009-2016 Dr. Buczynski’s research program focuses on identifying novel druggable targets for addiction and neurological disorders through mass spectrometry and behavioral pharmacology . His work integrates chemical biology , molecular pharmacology , and in vivo microdialysis to study molecular changes in the brain during chronic drug exposure. Key areas include nicotine dependence , ethanol withdrawal , and cross-talk between pain and addiction mechanisms. His recent publications highlight endocannabinoid system modulation , TRPV1/TRPA1 receptor activation in pain, and diacylglycerol lipase (DAGL) mechanisms in nicotine withdrawal. He employs both self-administration and forced exposure models to validate therapeutic targets. Prospective students can contact him directly through his lab’s website .

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Casper Hoogenraadمشاهده پروفایل

استاد

Utrecht UniversityNetherlands

Prof. Casper Hoogenraad is a full professor in Molecular Neuroscience at the Department of Cell Biology, Faculty of Science, Utrecht University. His research focuses on understanding how intracellular protein trafficking underlies neuronal development and function, with particular emphasis on the microtubule cytoskeleton, synaptic cargo trafficking, and synaptic plasticity. He leads an active research group within Utrecht University's Cell Biology department and collaborates extensively with other neuroscience research groups. Education: PhD, Erasmus University Rotterdam (1996-2001) Postdoc, Massachusetts Institute of Technology (2002-2005) Hoogenraad's research spans three main themes: cytoskeleton dynamics during neurodevelopment and synaptic plasticity, motor proteins and adaptors as regulators of synaptic transport, and psychiatric and neurologic disease disorders linked to intracellular transport. His work combines genetics, biochemistry, molecular, and cellular biology methods in in vitro (neuron cultures), ex vivo (brain slices), and in vivo (mice) systems, along with advanced microscopy techniques including immunofluorescent confocal microscopy, high-resolution live cell imaging, and photo-activated localization microscopy (PALM). Analysis of Hoogenraad's recent publications reveals a strong focus on microtubule organization, neuronal polarity, and the molecular mechanisms underlying synaptic function and dysfunction. His work frequently explores how disruptions in intracellular transport contribute to neurological disorders including Alzheimer's disease, schizophrenia, and autism spectrum disorders, with particular attention to the relationship between cytoskeletal organization and cargo transport in neuronal compartments. Scientific Awards and Memberships: ZonMW-VIDI (2004) European Young Investigators (EURYI) award (2005) NWO-ALW VICI (2011) ERC Consolidator grants (2013) FENS-Kavli Network of Excellence (2014) European Molecular Biology Organization (EMBO) (2015) Young Academy of Europe (YAE) (2015) IBRO Kemali Prize (2016) Hoogenraad leads a research group studying neuronal development and function, with a particular focus on how intracellular transport mechanisms contribute to both normal brain function and neurological disorders. His laboratory employs a multidisciplinary approach combining molecular, cellular, and systems neuroscience techniques to investigate the molecular basis of neuronal polarity, synaptic plasticity, and the pathogenesis of neurological disorders. He has secured significant research funding through prestigious grants including ERC Consolidator grants. The Hoogenraad lab operates within the Cell Biology department at Utrecht University, collaborating with other research groups focusing on cellular dynamics, biophysics, and neurobiology. The lab utilizes advanced microscopy techniques including immunofluorescent confocal microscopy, high-resolution live cell imaging (spinning disc microscopy and total internal reflection fluorescence microscopy), and quantitative analysis using advanced high-resolution microscopy (photo-activated localization microscopy). Current lab technicians include Phebe Wulf and Bart de Haan.

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Stephan J. Sigristمشاهده پروفایل

استاد

Free University of BerlinGermany

Prof. Stephan J. Sigrist is a Full Professor of Genetics at the Institute of Biology, Free University of Berlin. His lab focuses on synaptic active zone architecture, neuroplasticity, and aging-related neurodegeneration. He leads the Collaborative Research Center 958 on Membrane Scaffolding and co-directs NeuroCure, a DFG Cluster of Excellence at Charité. Education: PhD in Molecular Genetics (1997) and Habilitation (2005) from the University of Göttingen. Positions: Einstein Professor (2014–present), Spokesperson CRC 958 (2012–present), and Co-Director NeuroCure (2009–present). Research explores presynaptic mechanisms using Drosophila and mouse models, combined with STED microscopy. Key contributions include discoveries of Bruchpilot's role in active zones and spermidine's protective effects against age-related synapse decline. Grants: Over €6 million in funding, including DFG CRCs, Einstein Foundation, and ERC Advanced Grant (2025). Awards: Einstein Professorship, Best Habilitation Award, EMBO/HFSP Fellowships. Collaborations span structural biology (e.g., Stefan Hell), neurophysiology (David DiGregorio), and aging research (Frank Madeo).

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Philippe Campeauمشاهده پروفایل

دانشیار بالینی

University of MontrealCanada

Dr. Philippe Campeau is an Associate Clinical Professor in the Department of Pediatrics at the Faculty of Medicine, Université de Montréal. He is affiliated with CHU Sainte-Justine, a major pediatric hospital in Montreal, Quebec, where he works in the Medical Genetics Service. His clinical and research work focuses on genetic disorders affecting children, particularly in the areas of skeletal development and neurogenetics. Dr. Campeau obtained his Doctorate in Medicine from Laval University in Quebec (1998-2003) followed by specialty training in medical genetics at McGill University (2003-2008). He completed postdoctoral training at Baylor College of Medicine (2008-2013), which further developed his expertise in genetic research methodologies. His primary research interests include bone dysplasias , skeletal dysplasias , epilepsy , and epigenetic diseases . Dr. Campeau's laboratory identifies disease-causing genes, deciphers disease pathophysiology, and works to improve the management of children affected by these conditions. His work encompasses exome analysis , functional studies with cell lines and mouse models , and investigations into urea cycle abnormalities . He has made significant contributions to understanding genetic causes of conditions such as Genitopatellar syndrome (KAT6B), osteopetrosis, dysosteosclerosis (SLC29A3), osteogenesis imperfecta, early-onset osteoporosis (WNT1), Yunis-Varón syndrome (FIG4), and DOORS syndrome (TBC1D24). Dr. Campeau's publication record demonstrates a strong trajectory in medical genetics research, with numerous high-impact publications spanning from fundamental genetic discovery to translational research. His work spans skeletal disorders, neurodevelopmental conditions, and epigenetic mechanisms. Recent publications indicate an expanding focus on chromatin modifiers, DNA methylation patterns, and spliceosome function in neurodevelopmental conditions, reflecting the evolution of his research interests toward more complex molecular mechanisms. Dr. Campeau has received several research grants in recent years (6 starting in 2014) from organizations including the Fonds de la recherche en santé du Québec, Canadian Institutes of Health Research, and Fondation Grand Défi Pierre Lavoie. While specific students are not mentioned in the available information, as a clinical professor, he mentors medical students, residents, and research trainees in the Department of Pediatrics. His research is conducted as part of the 'Musculoskeletal Diseases and Rehabilitation' axis at CHU Sainte-Justine Research Center, where he collaborates with international research teams to identify disease-causing genes and develop better management strategies for children with genetic disorders.

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Teresa Puthusseryمشاهده پروفایل

دانشیار

University of California, BerkeleyUnited States

Dr. Teresa Puthussery is an Associate Professor in the School of Optometry & Vision Science at the University of California, Berkeley. Her research focuses on retinal neurobiology and neurophysiology, investigating how visual signals are encoded in healthy retinas and disrupted during degeneration. She uses advanced techniques like patch-clamp electrophysiology, immunohistochemistry, and microscopy to study retinal circuits, neurotransmitter receptors, and ion channels. Dr. Puthussery teaches courses on vision science anatomy, physiology, and problem-based learning, including VISION SCIENCE 206B/C and 260C. Her research explores questions such as how retinal neurons extract motion/spatial details, how photoreceptor mutations cause degeneration, and how inner retinal circuits adapt post-photoreceptor loss. Recent work includes studies on ON-type direction-selective ganglion cells, optogenetic therapy for vision restoration, and calcium dynamics in foveal ganglion cells post-degeneration. She collaborates on projects involving primate and rodent models, contributing to understanding retinal disease mechanisms and therapeutic targets. Dr. Puthussery’s lab (retinalab.berkeley.edu) emphasizes translational research, bridging basic science and clinical applications. Her work has been published in journals like Nature and Cell Reports , with a focus on retinal degeneration, synaptic plasticity, and optogenetic interventions. She actively participates in training future vision scientists through Berkeley’s Optometry program and oversees GSI affairs as a faculty advisor.

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Jessica J. Walshمشاهده پروفایل

استادیار

University of North Carolina at Chapel HillUnited States

Jessica J. Walsh, PhD is an Assistant Professor in the Department of Pharmacology at the University of North Carolina at Chapel Hill School of Medicine and a member of the UNC Neuroscience Center. She leads the Walsh Lab, which focuses on understanding neural circuit mechanisms underlying motivated social behavior using a multi-level approach to elucidate the molecular and circuit mechanisms that govern social interactions and their alterations in disease states. Dr. Walsh earned her B.A. in Neuroscience & Behavior from Columbia University, where she began her research journey volunteering in Dr. Gerald Fischbach's laboratory. During her graduate work, she explored neural circuit mechanisms underlying social stress susceptibility at the Icahn School of Medicine at Mount Sinai under Dr. Ming-Hu Han. Prior to joining UNC, she completed her postdoctoral fellowship at Stanford University with Dr. Robert Malenka, investigating neural circuit mechanisms in genetic mouse models with social deficits. Her research focuses on neural circuit mechanisms underlying motivated behavior, neurodevelopmental and psychiatric disorders, and functional/anatomical brain mapping. The Walsh Lab specifically uses genetic mouse models to investigate how genetic mutations and experience lead to circuit adaptations that govern impaired behavior seen in autism spectrum disorders. They combine whole brain optical clearing methods, light sheet microscopy, in vivo imaging, and machine learning based behavioral analysis to elucidate neural adaptations responsible for motivated behavior. Her publication record demonstrates a strong focus on neural circuits related to social behavior, with particular emphasis on autism spectrum disorders, serotonin and dopamine signaling, and the neural basis of prosocial behaviors. She has published extensively in high-impact journals including Nature, Nature Neuroscience, PNAS, and Neuropsychopharmacology, with research spanning from molecular mechanisms to circuit-level analyses of behavior. Dr. Walsh mentors several trainees in her lab, including a postdoctoral fellow, multiple graduate students, and numerous undergraduate researchers. Her lab team includes researchers with diverse interests spanning from molecular biology to machine learning applications in neuroscience. The lab actively recruits postdocs and graduate students interested in joining their research on motivated behavior and psychiatric disorders. The Walsh Lab employs a comprehensive research approach including genetic manipulation, whole brain activity mapping, viral tracing, slice physiology, optogenetics, chemogenetics, fiber photometry, and machine learning based behavioral classification to gain a nuanced understanding of neural circuits involved in motivated social behavior.

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Michelle CD Bridiمشاهده پروفایل

استادیار

West Virginia UniversityUnited States

Michelle CD Bridi is an Assistant Professor in the Department of Neuroscience at West Virginia University School of Medicine , with a joint affiliation at the Rockefeller Neuroscience Institute . Her research integrates synaptic plasticity , sleep physiology , and neurological conditions to investigate dynamic synaptic regulation under typical and atypical states. Education: BS , McGill University, 2006 PhD , University of Pennsylvania, 2013 Research Focus: The Bridi Lab explores how daily oscillations in excitation/inhibition (E/I) balance are disrupted in Autism Spectrum Disorder (ASD) , aging , and post-stroke states . Current projects address: 1) synaptic adaptation to sleep/wake cycles, 2) E/I imbalance in neurodevelopmental disorders, and 3) molecular mechanisms maintaining neuronal firing rate homeostasis. Publication Trends: Recent work spans REM sleep plasticity , autism models , and neurodegenerative interventions , emphasizing synaptic oscillations , NMDA receptor pathways , and gene therapy applications. Collaborative efforts with Morgan Bridi's lab extend findings to stress and stroke contexts. Grants & Collaborations: Research is funded by NIH/NIGMS , BBRF , and NSF . The lab actively collaborates with cross-institutional teams and is recruiting postdocs and students for ongoing studies.

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Sonia Mayoralمشاهده پروفایل

استادیار

Brown UniversityUnited States

Sonia Mayoral is the Robert J. and Nancy D. Carney Assistant Professor of Neuroscience at Brown University. Her research focuses on studying cell-cell interactions in the brain, particularly the development and function of oligodendrocytes – glial cells critical for myelin formation. She explores how these cells contribute to myelination, remyelination processes, and their roles in neurological disorders like multiple sclerosis. Her work integrates cellular neuroscience, immunology, and drug screening methodologies. Research interests include glial cell biology, neuron-glial interactions, and the molecular mechanisms governing myelin repair. She investigates how environmental cues and signaling pathways regulate oligodendrocyte differentiation and function. Notable projects involve developing high-throughput screening platforms for MS therapeutics and studying sex-specific responses to neurodegenerative challenges. Her lab’s recent work includes clinical trials (Re-WRAP) evaluating Bazedoxifene for remyelination in women, and fundamental studies on regulatory T cell roles in myelin regeneration. She also examines how mechanical stimulation and epigenetic changes influence oligodendrocyte behavior. Her research bridges basic science and translational efforts, aiming to advance treatments for myelin-related disorders. Dr. Mayoral’s lab is active at Brown University, with a dedicated website detailing ongoing projects and collaborations. While no specific grants or students are listed here, her work reflects a strong focus on interdisciplinary approaches to neurodegenerative disease mechanisms.

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Yukiko Gotohمشاهده پروفایل

استاد

IT University of CopenhagenDenmark

Yukiko Gotoh is a Professor at the Department of Pharmaceutical Sciences, Graduate School of Pharmaceutical Sciences, The University of Tokyo. She serves as the Deputy Director and Principal Investigator at the International Research Center for Neurointelligence (IRCN). Her research focuses on understanding the mechanisms that regulate neural stem/progenitor cell fate during embryonic brain development and in the adult brain. Dr. Gotoh's research interests include: Genetic and epigenetic regulation of neural stem/progenitor cell fate Neuronal maturation processes Genesis and maintenance of adult neural stem cells Relevance of neural stem/progenitor cell dysregulation in neurodevelopmental disorders such as autism spectrum disorders Investigation of mechanisms regulating neural stem-progenitor cell fate during neocortical development Genetic and epigenetic regulation of neuronal activation Analysis of Dr. Gotoh's recent publications reveals a strong focus on neural stem cell biology, epigenetic regulation, and neurodevelopmental disorders. Her work demonstrates how chromatin modifiers like Polycomb group proteins and HMGA proteins regulate neural stem cell fate decisions during brain development. A significant portion of her research explores the embryonic origins of adult neural stem cells and how dysregulation of these processes contributes to conditions like autism spectrum disorders and schizophrenia. Her laboratory also investigates the basic mechanisms of cellular responses to viral infection in the brain and their relevance to neurodevelopmental disorders. Dr. Gotoh has made significant contributions to understanding: The role of Polycomb group proteins in neural development How chromatin modifiers regulate neurogenic potential Cell cycle regulation in neural stem cells The PDK1-Akt pathway in neuronal migration Layer-specific heterogeneity of astrocytes Mechanisms underlying schizophrenia-related abnormalities Dr. Gotoh's laboratory conducts research on multiple fronts related to neural development and stem cell biology. Her team investigates: Mechanisms regulating neural stem-progenitor cell fate during neocortical development Genetic and epigenetic regulation of neuronal activation The embryonic origin of adult neural stem cells Dysregulation of neural stem-progenitor cell and neuronal fate in neurodevelopmental disorders Innate immune responses in the brain

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Miler T. Leeمشاهده پروفایل

دانشیار

University of PittsburghUnited States

Miler T. Lee is an Associate Professor at the University of Pittsburgh , focusing on gene regulation during early embryonic development through high-throughput experimental and computational genomics. He earned his Ph.D. in Genomics and Computational Biology in 2009 from the University of Pennsylvania under Dr. Junhyong Kim, followed by postdoctoral work with Dr. Antonio Giraldez at Yale University. Joining the university in 2016, his research spans maternal-to-zygotic transition (MZT), RNA stability, pluripotency networks, and evolutionary developmental biology, utilizing model organisms like zebrafish, Xenopus, and Hydractinia symbiolongicarpus. Key Research Themes: Maternally inherited RNA dynamics during embryogenesis Mechanisms of RNA degradation and transcriptome remodeling Evolution of pluripotency networks in hybrid species Role of zinc signaling in fertilization barriers Computational tools for RNA regulation and sensing Scientific Awards: Pan-American Society for Evolutionary Developmental Biology Junior Faculty Award (2024) Outstanding New Investigator – International Xenopus Board (2023) Basil O'Connor Scholar – March of Dimes (2017-2019) Recent publications highlight his work on enhancer classification, RNA degradation mechanisms, and cross-species MZT comparisons. His lab develops innovative methods like RESA for regulatory sequence analysis and studies evolutionary divergence in RNA localization patterns. While the articles span computational and experimental approaches, they consistently address RNA's role in cellular identity, developmental timing, and evolutionary adaptation. Applications include understanding pluripotency, designing RNA biosensors, and elucidating fertilization barriers. Prospective Ph.D. students are encouraged to contact him for opportunities in gene regulation, development, evo-devo, and computational genomics.

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Barbara L. Hempsteadمشاهده پروفایل

استاد

Cornell UniversityUnited States

Dr. Barbara L. Hempstead is a Professor of Neuroscience and Medicine at Weill Cornell Medical College, where she has held positions since 2001 and 2002 respectively. Her research focuses on neurotrophin signaling mechanisms, particularly the roles of BDNF and its receptors in neuroinflammation, synaptic plasticity, and neurodegenerative diseases. She has made significant contributions to understanding proBDNF/proNGF signaling pathways in neuronal apoptosis and vascular biology. Education: M.D., Ph.D., Washington University School of Medicine (1982) B.A., Tufts University (1976) Dr. Hempstead's work bridges molecular neuroscience and cardiovascular biology, with a particular interest in receptor stoichiometry (p75NTR, TrkB), neurotrophin-induced synaptic remodeling, and therapeutic applications of neurotrophin modulators in Huntington's disease and post-seizure neuronal injury. Her lab investigates how genetic variants like BDNF Val66Met influence anxiety-related behaviors, social memory, and neurodegenerative disease progression through altered neurotrophin trafficking and signaling. Her recent publications highlight neuroinflammatory mechanisms (2023), immune-neurotrophin interactions (2022), and molecular pathways involving BDNF prodomain structure (2020) and SorCS2-mediated receptor trafficking (2017-2020). While no scientific awards are explicitly mentioned in the scraped text, her funded research (National Institute on Aging, NIMH) demonstrates sustained recognition of her work in neurotrophin biology. Dr. Hempstead's lab develops in vitro and in vivo models to study neurotrophin-receptor dynamics, including 3D culture systems for angiogenesis research and transgenic mouse models for Huntington's disease. Her interdisciplinary approach combines molecular neurobiology with vascular physiology to uncover novel therapeutic targets for neurological and cardiovascular conditions.

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