معرفی
Michelle CD Bridi is an Assistant Professor in the Department of Neuroscience at West Virginia University School of Medicine, with a joint affiliation at the Rockefeller Neuroscience Institute. Her research integrates synaptic plasticity, sleep physiology, and neurological conditions to investigate dynamic synaptic regulation under typical and atypical states.
Education:
- BS, McGill University, 2006
- PhD, University of Pennsylvania, 2013
Research Focus: The Bridi Lab explores how daily oscillations in excitation/inhibition (E/I) balance are disrupted in Autism Spectrum Disorder (ASD), aging, and post-stroke states. Current projects address: 1) synaptic adaptation to sleep/wake cycles, 2) E/I imbalance in neurodevelopmental disorders, and 3) molecular mechanisms maintaining neuronal firing rate homeostasis.
Publication Trends: Recent work spans REM sleep plasticity, autism models, and neurodegenerative interventions, emphasizing synaptic oscillations, NMDA receptor pathways, and gene therapy applications. Collaborative efforts with Morgan Bridi's lab extend findings to stress and stroke contexts.
Grants & Collaborations: Research is funded by NIH/NIGMS, BBRF, and NSF. The lab actively collaborates with cross-institutional teams and is recruiting postdocs and students for ongoing studies.
