جست‌وجوی استاد و پژوهشگر

• Tissue Engineering
• Biofabrication
• Cartilage Regeneration
• +۳ مورد دیگر

Prof. Marcy Zenobi-Wong is a Full Professor at ETH Zurich's Department of Health Sciences and Technology, specializing in biofabrication and tissue engineering. Her research focuses on cartilage regeneration using advanced biomaterials, including nanofilm coatings and 3D printing techniques. She holds patents in tissue engineering and has pioneered methods like filamented light (FLight) biofabrication for creating anisotropic tissues. Her academic journey includes a B.Sc. from MIT (1985), M.Sc. and Ph.D. from Stanford (1987, 1990), followed by postdoctoral work at the University of Michigan. She leads the Biofabrication Group at ETH, developing therapies for joint repair and regenerative medicine. Courses taught include Biomedical Engineering and Materials and Mechanics in Medicine . Research highlights include engineered hydrogels for cartilage protection, CRISPR-driven gene editing in chondrocytes, and biohybrid neural interfaces. Her work bridges material science, cell biology, and clinical applications, with a focus on translational medicine. Collaborative projects involve creating elastic cartilage grafts for microtia reconstruction and volumetric printing of complex tissue constructs.

Carmen Bergomمشاهده پروفایل

دانشیار

• Radiation Oncology
• Breast Cancer
• Tumor Microenvironment
• +۵ مورد دیگر

Carmen Bergom, MD, PhD, is an Associate Professor of Radiation Oncology at Washington University School of Medicine (WashU Medicine), where she joined the faculty in 2020. She holds secondary appointments in the Division of Cancer Biology and the Siteman Cancer Center. Her research focuses on leveraging genetic models to improve radiation therapy efficacy while mitigating radiation-induced cardiotoxicity , particularly in breast cancer patients. Key areas include radiation biology , tumor microenvironment , and cardio-oncology . Recent publications highlight her work in genetic mapping of radiation sensitivity (e.g., rat chromosome 3 variants), innovative imaging techniques (e.g., integrin-targeted PET), and clinical trial design for cardiovascular risk stratification. Her laboratory has pioneered the first genetic studies of radiation-induced cardiac dysfunction. Scientific awards include the Michael Fry Research Award (2021) and recognition as a Top Doctor in America (2018, 2019). She serves as Chair of the ASTRO Science Council Scientific Review Panel and co-chair of the Clinical and Experimental Research in Radiation Oncology meeting at ESTRO. Dr. Bergom treats breast cancer patients clinically and mentors students across all levels (undergraduate to postdoctoral). Her work bridges basic research with clinical applications , aiming to develop biomarkers and therapeutic targets for radiation oncology.

• Nuclear Magnetic Resonance (NMR)
• In vivo imaging
• MRI pulse sequence development
• +۷ مورد دیگر

Professor Guy Williams is a leading academic at the University of Cambridge with a focus on imaging science and clinical neurosciences, affiliated with Downing College and the Wolfson Brain Imaging Centre . Holding a PhD in Physics from his initial Natural Sciences degree, he specializes in nuclear magnetic resonance (NMR) and MRI techniques for brain imaging. Education: BA, PhD in Physics His research centers on non-invasive imaging of brain structure and function, particularly in traumatic brain injury (TBI) and dementia. His work involves developing novel MRI pulse sequences and advanced data analysis algorithms, including AI-based diagnostic tools. He leads studies on white matter integrity post-trauma, longitudinal dementia assessment, and applications of MRI in disorders of consciousness and addiction. Recent publications highlight collaborations in traumatic brain injury outcomes, AI-guided dementia prediction, and neuroimaging of post-COVID cognitive deficits. His team's work on ultra-high field laminar fMRI and distortion correction methods has advanced clinical neuroscience applications. Key techniques include diffusion tensor imaging (DTI), 7 Tesla MRI, and positron emission tomography (PET/MR). His research spans from basic NMR physics to clinical translation, with a strong emphasis on multi-site studies and real-world diagnostic implementation.

Simon Schäferمشاهده پروفایل

استاد

• Neuroscience
• Developmental Biology
• Stem Cell Research
• +۴ مورد دیگر

Prof. Dr. Simon Schäfer leads the Schäfer Lab at the Technische Universität München , focusing on engineering advanced organoid systems to study human brain development, disease modeling, and repair mechanisms. His work bridges stem cell biology, gene editing, and bioengineering to develop personalized therapies for brain disorders. Stem Cell & Organoid Technology Neurodevelopmental Mechanisms Neurodegenerative Disease Models Gene Editing & Neuroimmune Interactions Translational Neuroscience Recent research emphasizes brain organoid development, microglia phenotypes, and neurodevelopmental timing anomalies in autism. His team’s work also explores zika virus interactions with glioblastoma stem cells and neuronal plasticity in psychiatric disorders. Scientific awards and funding include support from the Deutsche Forschungsgemeinschaft (DFG), Brain & Behavior Research Foundation (BBRF), and Munich Cluster for Systems Neurology (SyNergy). Collaborations span institutions like the TUM Center for Organoid Systems. Advises 6 students (2 PhD, 1 MSc, 3 associated) Labs include Schäfer Lab, COS@TranslaTUM Contact: simon.schafer@tum.de

• DNA Repair
• Mitochondrial Biology
• Aging
• +۵ مورد دیگر

Vilhelm Bohr is an Affiliate Professor at the Department of Cellular and Molecular Medicine , University of Copenhagen, affiliated with the Molecular Aging Program and Center for Healthy Aging . His research explores the interplay between DNA maintenance , mitochondrial biology , and aging , particularly in age-associated neurodegeneration and Alzheimer’s disease. Research Interests include: Molecular mechanisms linking NAD + metabolism to mitochondrial dysfunction and neurodegeneration Role of tau pathology in DNA damage and mitochondrial stress Impact of Aprataxin (APTX) and RECQL4 helicase defects on mitochondrial DNA integrity Pharmacological strategies to improve mitochondrial health via autophagy modulation Publications (2025-2024) span topics like NAD + biosynthesis, Werner/Rothmund-Thomson syndromes, tau nuclear functions, and mitochondrial turnover, with high citations and media attention. Collaborations extend to clinical tumor samples and CRISPR-based disease models.

Giorgio Ascoliمشاهده پروفایل

استاد

• Computational Neuroanatomy
• Neuroinformatics
• Neuronal Morphology
• +۵ مورد دیگر

Giorgio Ascoli is a University Professor in the Department of Bioengineering at George Mason University, where he has been since 1997. He is the Founding Director of the Center for Neural Informatics, Structures, & Plasticity (CN3) and Founding Editor-in-Chief of the journal Neuroinformatics . His affiliations span computational neuroanatomy, neuroinformatics, and hippocampal modeling. Education : PhD in Biochemistry and Neuroscience (1996), Scuola Normale Superiore; MS in Chemistry and Biochemistry (1993), Pisa University; BS in Chemistry and Physics (1991), Scuola Normale Superiore. Dr. Ascoli investigates the relationship between brain structure, activity, and function from cellular to circuit levels. His research focuses on anatomically plausible neural networks to model mammalian brains, particularly the hippocampus, with implications for understanding human memory and consciousness . He pioneered computational neuroanatomy, developing tools like L-Neuron for neuronal shape modeling and curating NeuroMorpho.Org , a central repository for digitally reconstructed neurons. His recent publications emphasize neuronal classification , connectome analysis , and biologically informed machine learning . Awards include the 2012 Outstanding Faculty Award (Virginia), 2022 AIMBE fellowship , and 2023 Presidential Faculty Excellence Awards . He has mentored over 20 graduate students and postdoctoral fellows, with funding from NIH, NSF, DARPA, and private foundations. Scientific Contributions : Over 137 peer-reviewed articles, 4 patents, 2 authored/edited books, and leadership in NeuroMorpho.Org and Hippocampome. Grants : $20M+ in cumulative funding, including NIH R01s, NSF BRAIN EAGERs, and Burroughs-Wellcome Trust support. Labs : Leads the Computational Neuroanatomy Group within CN3, focusing on hippocampal modeling, neuronal morphology, and consciousness theories.

Istvan Modyمشاهده پروفایل

استاد

• Neuroscience
• Neurology
• Pharmacology
• +۱۲ مورد دیگر

Istvan Mody is a Professor at the University of California, Los Angeles (UCLA) with appointments in the Department of Neurology and Department of Physiology . His research focuses on synaptic signaling in health and disease, including mechanisms of GABAergic transmission, calcium homeostasis, and their roles in neurological disorders such as epilepsy, Alzheimer's disease, Huntington's disease, stress, alcoholism, and postpartum depression. He utilizes advanced techniques like patch-clamp electrophysiology, neuroanatomical and immunohistochemical methods, and molecular biology in animal models and human brain tissue . Research Interests: Dr. Mody investigates the physiology, pharmacology, and pathology of synaptic transmission and extrasynaptic receptor activation , with a particular emphasis on GABA(A) receptors and their subunit-specific modulation. His work explores how disruptions in excitation-inhibition balance contribute to neurological diseases, including mechanisms of tonic inhibition , calcium signaling , and neurosteroid interactions . He also studies the effects of chronic stress and hormonal fluctuations on neural excitability and behavior. Publications Trends: Recent studies highlight his work on gamma oscillations in Alzheimer's models, microglial dynamics , and rehabilitation strategies for stroke. His lab develops optical tools like dqGEVI for neuronal activity monitoring and investigates human brain organoids to model network dysfunction in epilepsy and intellectual disability. Laboratory Location: 635 Charles Young Dr S, Los Angeles, CA 90095, United States.

Ilse Dewachterمشاهده پروفایل

استاد

• Alzheimer's Disease
• Neurodegenerative Diseases
• Therapeutic Development
• +۶ مورد دیگر

Prof. Ilse Dewachter is the head of the Biomed Neuroscience research group at Hasselt University (UHasselt), specializing in Alzheimer’s therapy and prevention for over 25 years. Her work focuses on multi-targeted therapies targeting tau, inflammation, and ApoE, alongside pioneering research into disease prevention via blood-based biomarkers. Recent studies explore a protective APOE3ch mutation that halted Alzheimer’s progression in a patient, offering hope for new treatments. Research Interests: - Alzheimer’s disease mechanisms (Abeta, tau, inflammation) - Multi-target therapies and biomarker development - Neurodegenerative disease prevention strategies - Genetic mutations impacting disease progression Articles Overview: Her most recent work (2025-2022) addresses neuroinflammation, tau propagation models, and AI-driven neuroimaging. Key themes include APOE genetics, blood-brain barrier dynamics, and exercise impacts on cognition. Funding & Grants: Current projects require significant investment for advanced biomarker equipment and clinical trials. A notable €300,000 grant funded research on brain lipid metabolism’s role in Alzheimer’s. Labs & Teams: Leads the BIOMED Neuroscience group at UHasselt, collaborating internationally on preclinical models and drug development.

Parth Chansoriaمشاهده پروفایل

مدرس

• Biofabrication
• Tissue Engineering
• Regenerative Medicine
• +۷ مورد دیگر

Dr. Parth Chansoria is a Lecturer at the Department of Health Sciences and Technology at ETH Zürich, where he leads biofabrication research within the Tissue Engineering and Biofabrication (TEB) group. His work focuses on structured light technology for regenerative medicine applications, including in vivo bioprinting and microgravity-based tissue engineering. He holds Ambizione and Spark grants from the Swiss National Science Foundation and has pioneered innovations in light-guided biofabrication, collagen-based resins, and anisotropic tissue design. Research domains include: Filamented light biofabrication for aligned tissues Minimally invasive light-based in vivo bioprinting Musculoskeletal tissue engineering in microgravity Isotonic collagen-based photocrosslinkable resins He has secured over 6 patents and received prestigious awards including the ISBF Early Career Investigator Award (2022), Marie Curie Actions Fellowship (2021), and SME 30 Under 30 recognition (2021). His interdisciplinary research bridges bioengineering, materials science, and clinical applications. Key collaborations include projects at UNC Chapel Hill (USA) and NC State (USA), where he developed biomimetic patches for dynamic organ pathologies and ultrasound-assisted cell patterning. His lab explores novel bioinks, hybrid fabrication techniques, and translational applications in regenerative medicine.

Teresa Puthusseryمشاهده پروفایل

دانشیار

• Retinal Neurobiology
• Neurophysiology
• Retinal Degeneration
• +۳ مورد دیگر

Dr. Teresa Puthussery is an Associate Professor in the School of Optometry & Vision Science at the University of California, Berkeley. Her research focuses on retinal neurobiology and neurophysiology, investigating how visual signals are encoded in healthy retinas and disrupted during degeneration. She uses advanced techniques like patch-clamp electrophysiology, immunohistochemistry, and microscopy to study retinal circuits, neurotransmitter receptors, and ion channels. Dr. Puthussery teaches courses on vision science anatomy, physiology, and problem-based learning, including VISION SCIENCE 206B/C and 260C. Her research explores questions such as how retinal neurons extract motion/spatial details, how photoreceptor mutations cause degeneration, and how inner retinal circuits adapt post-photoreceptor loss. Recent work includes studies on ON-type direction-selective ganglion cells, optogenetic therapy for vision restoration, and calcium dynamics in foveal ganglion cells post-degeneration. She collaborates on projects involving primate and rodent models, contributing to understanding retinal disease mechanisms and therapeutic targets. Dr. Puthussery’s lab (retinalab.berkeley.edu) emphasizes translational research, bridging basic science and clinical applications. Her work has been published in journals like Nature and Cell Reports , with a focus on retinal degeneration, synaptic plasticity, and optogenetic interventions. She actively participates in training future vision scientists through Berkeley’s Optometry program and oversees GSI affairs as a faculty advisor.

Caryl Sortwellمشاهده پروفایل

استاد

• Parkinson's Disease
• Neurotrophic Factors
• Alpha-Synuclein Pathology
• +۴ مورد دیگر

Caryl E. Sortwell is a Professor of Translational Neuroscience and Edwin A. Brophy Endowed Chair in Central Nervous System Disorders at Michigan State University's College of Human Medicine. She leads the Sortwell Lab within the Neuroscience Program and Grand Rapids Research Center, focusing on Parkinson's disease (PD) therapeutics. Education : B.S. in Psychology/Pre-medicine (University of Illinois, 1987), Ph.D. in Anatomy and Cell Biology/Neurobiology (University of Illinois at Chicago, 1994) Positions : Assistant/Associate Professor at Rush University Medical Center (1997-2005), Associate Professor at University of Cincinnati (2005-2009), Professor at MSU College of Human Medicine (2009-present) Her research investigates alpha-synuclein pathology in PD using preformed fibril models to study neurodegeneration, neuroinflammation, and therapeutic interventions. She explores neurotrophic factors like BDNF, gene therapies targeting CaV1.3 channels, and deep brain stimulation mechanisms. Her work emphasizes precision medicine approaches to optimize treatment outcomes. Scientific contributions include methodological advancements in neurochemical sensing with diamond electrodes and viral vector delivery systems. Key collaborations include research with Dr. Joe Patterson on alpha-synuclein genetic consequences. Technical Expertise : Immunohistochemistry, stereotactic surgery, in vivo neurotoxicant models, protein analysis (Western blot/ELISA), droplet digital PCR, and neuroinflammatory profiling

• Neurodegenerative Diseases
• Environmental Toxicology
• Neurotoxicology
• +۴ مورد دیگر

Dr. Douglas Lobner is a Research Professor in the Department of Biomedical Sciences at Marquette University, College of Health Sciences. His research focuses on neurodegenerative disease mechanisms, environmental toxin interactions, and dental material toxicity. He investigates how environmental factors like mercury, pesticides, and BMAA interact with genetic predispositions to cause neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and ALS, particularly through the cystine/glutamate transporter (system xc-). His work also explores dental pulp capping materials, emphasizing growth factor-enhanced repair mechanisms and system xc- regulation to prevent root canal procedures. Key collaborations involve studies on glutamate signaling, neurotoxicant synergy, and drug-induced neuroplasticity. Published research includes over 14 studies from 2009–2014, emphasizing system xc- regulation by growth factors, neurotoxin synergies (e.g., methylmercury and BMAA), and dental material toxicity mitigation strategies. His lab contributes to the Neuroscience Collaboratory and Integrative Neuroscience Research Center at Marquette.

• Neuroscience
• Neurodegenerative Diseases
• Alzheimer's Disease
• +۳ مورد دیگر

Hideyuki Takahashi is an Associate Research Scientist in the Department of Neuroscience at Yale University School of Medicine. He holds a PhD from Waseda University (2005) and has established himself as a prominent researcher in neurodegenerative diseases, particularly focusing on lysosomal biology and protein aggregation mechanisms. Dr. Takahashi's research primarily investigates the role of progranulin, TMEM106B, and other molecular players in neurodegenerative conditions including Alzheimer's disease, frontotemporal dementia, and tauopathies. His work spans multiple approaches from molecular and cellular neuroscience to animal models of disease. His recent publications demonstrate a strong focus on lysosomal dysfunction in neurodegeneration, with particular attention to how TMEM106B interacts with other proteins to influence disease progression. The research trends show increasing emphasis on therapeutic interventions targeting specific molecular pathways involved in protein aggregation and synaptic loss. ORCID: 0009-0004-4969-977X Dr. Takahashi maintains active collaborations with several leading researchers at Yale, most notably with Stephen Strittmatter (with whom he has 16 common publications), as well as Anita Huttner, Anthony Koleske, and Le Zhang. His research program appears well-integrated within Yale's neuroscience community, contributing significantly to our understanding of neurodegenerative disease mechanisms.

Manu Sharmaمشاهده پروفایل

دانشیار

• Neuroscience
• Neurodegenerative Diseases
• Synaptic Transmission
• +۵ مورد دیگر

Manu Sharma is an Associate Professor of Neuroscience at the Brain and Mind Research Institute , Weill Cornell Medical College (2024–present). His research focuses on the molecular mechanisms underlying neurodegenerative diseases, particularly tauopathies and synucleinopathies (e.g., Alzheimer’s and Parkinson’s diseases), synaptic transmission, and protein aggregation. Education: Ph.D., University of Toronto (2005) B.Sc., University of Toronto (1998) Research Interests: Dr. Sharma investigates how physiological and pathological modifications of tau and α-synuclein proteins contribute to neurodegeneration. His work explores synaptic vesicle dynamics, chaperone-mediated protein stabilization, and the role of lysosomal pathways in disease progression. Grants: He has secured major funding as Principal Investigator and Co-Investigator from the National Institute on Aging and National Institute of Neurological Disorders & Stroke (2024–2029) for studies on tau proteostasis, synucleinopathies, and small molecule inhibitors targeting neurodegenerative pathways. Labs & Teams: Affiliated with the Brain and Mind Research Institute, Dr. Sharma collaborates on multidisciplinary projects involving synaptic biology, protein quality control, and neurodegeneration models.

Franz Lennard Ricklefsمشاهده پروفایل

استاد

• Neurosurgery
• Neuro-oncology
• Molecular Neurobiology
• +۵ مورد دیگر

Prof. Dr. med. Franz Lennard Ricklefs is a Senior Physician and Head of the Working Group at the Department of Neurosurgery, University of Hamburg Faculty of Medicine. He is a Medical Specialist in Neurosurgery with cross-disciplinary expertise in neuro-oncology, molecular pathology, and extracellular vesicle research. Affiliations: University Medical Center Hamburg-Eppendorf (UKE), European Liquid Biopsy Society (ELBS), International Consortium on Meningiomas (ICOM) Research Interests: His work focuses on neurosurgical oncology, particularly glioblastoma and meningioma pathobiology. He investigates DNA methylation patterns, extracellular vesicle biomarkers, and liquid biopsy implementation in clinical neuro-oncology. Additional interests include surgical outcomes for epilepsy and aneurysm management. Article Trends: Over the last decade, Dr. Ricklefs has published extensively on: Extracellular vesicle applications as liquid biopsy markers DNA methylation subclasses for glioblastoma and meningioma Multicenter surgical outcome benchmarking Immune evasion mechanisms in neuro-oncology Technological innovations in neurosurgical visualization Molecular characterization of rare CNS tumors Professional Contributions: He co-authored the MISEV2023 guidelines for extracellular vesicle studies and participates in international consensus reviews for meningioma classification. His collaborations span institutions across Europe and North America.