جست‌وجوی استاد و پژوهشگر

Katie Atkinsمشاهده پروفایل

استاد

• Infectious Disease Epidemiology
• Mathematical Modelling
• Phylogenetics
• +۵ مورد دیگر

Katie Atkins is Professor (Personal Chair) of Infectious Disease Epidemiology at the University of Edinburgh, holding a Chancellor's Fellowship within the Usher Institute of the College of Medicine and Veterinary Medicine. She maintains an external Professorship at the London School of Hygiene & Tropical Medicine until June 2026. Education: BSc in Mathematics MSc in Mathematical Biology PhD in Biological Sciences Research Focus: Dr. Atkins pioneers evolutionary epidemiology through mathematical modelling and phylogenetics to decode infectious disease dynamics. Her work targets HIV transmission bottlenecks , antimicrobial resistance evolution , and vaccine-induced pathogen shifts , with emphasis on unobservable early-infection processes. Current projects integrate deep sequencing with quantitative analysis to address critical public health questions. Publication Trends: Recent work (2023-2024) demonstrates methodological convergence across HIV, measles, RSV, and SARS-CoV-2 research. Key patterns include phylogenetic bottleneck analysis for transmission routes, spatial network modelling for vaccine-preventable outbreaks, and cost-effectiveness frameworks for novel immunization strategies – reflecting her integrative approach to epidemic dynamics. Scientific Awards: No specific awards were documented in the source materials. Supervision & Grants: Dr. Atkins mentors PhD candidates in Wellcome's Hosts, Pathogens and Global Health DTP and MRC's Precision Medicine DTP. Her research portfolio includes: ERC Starting Grant (HIV ECLIPSE, 2018-2024): Quantifying early HIV transmission events Wellcome Trust Programme (2021-2026): Tracking vaccine-driven antimicrobial resistance in Vietnam Cluster randomized trials for pneumococcal conjugate vaccines Research Collective: She leads a multidisciplinary team comprising postdoctoral researchers (Villabona-Arenas, Lepper, Hackman) and PhD students at the Centre for Global Health, driving collaborative work on pathogen evolution and intervention impact.

Sofya Aptekarمشاهده پروفایل

دانشیار

• Immigration
• Gentrification
• Public Space
• +۶ مورد دیگر

Dr. Sofya Aptekar is an Associate Professor of Urban Studies at St. John's University (CUNY), with a PhD in Sociology from Princeton University (2010) and a BA from Yale University (2001). Her research focuses on immigration, gentrification, public space, military and US empire dynamics, and alternatives to capitalism. She is the author of Green Card Soldier: Between Model Immigrant and Security Threat and The Road to Citizenship: What Naturalization Means for Immigrants and the United States , and co-author of Lend and Rule: Fighting the Shadow Financialization of Public Universities . She actively participates in labor movements through the Public Higher Education Workers network with Labor Notes and serves as a delegate of the Professional Staff Congress-CUNY. Research Interests : Dr. Aptekar explores how immigration policy shapes undocumented status, the role of militarism in citizenship narratives, and the impact of neoliberal policies on higher education. Her work bridges sociological theory with grassroots activism, particularly in urban spaces like community gardens and libraries. She critically examines the intersections of race, class, and state power. Recent Work : Her recent articles analyze debt and military labor, DACA's educational impacts, and the legal violence faced by undocumented Chinese migrants. She has received grants including the 2024 Social Practice CUNY Faculty Fellowship and the 2017 T. Grant Foundation award for research on immigration and education. Awards & Grants 2024-2025 Social Practice CUNY Faculty Fellow 2023-2024 CUNY Black, Racial, and Ethnic Studies Research Faculty Fellow 2019-20 Russell Sage Foundation Visiting Fellow Advising & Advocacy : Co-authoring studies with Amy Hsin on undocumented students at CUNY, she advocates for systemic changes in higher education financing and labor rights. Her activism includes organizing with the Coalition against Campus Debt and contributing to policy debates on immigration reform. Labs/Teams : Engaged with the Public Higher Education Workers network and the Scholar Strategy Network, she collaborates to advance equity in urban spaces and public institutions.

• Logic
• Philosophy of Science
• History of Philosophy
• +۴ مورد دیگر

Laszlo Polos is a distinguished Professor holding dual appointments at Károli Gáspár Reformed University in Budapest (Faculty of Humanities, Department of Liberal Arts and Art Studies) and Durham University in the UK (Business School, Department of Management). Born in Budapest in 1955, he earned his PhD in Philosophy in 1993 and has established himself as a leading scholar bridging logical philosophy and organizational theory. His educational background includes dual MA degrees in Mathematics-Physics and Philosophy from Eötvös Loránd University (1980, 1982), followed by doctoral studies culminating in a PhD in Philosophy in 1993. He also completed Basic Dutch studies at the University of Amsterdam in 1993. Professor Polos's research spans the intersection of formal logic and social sciences, with primary interests in Logic, Philosophy of Science, History of Philosophy, Sociology, Organization Theory, Social Science Methodology, and Cognitive Sociology. His work uniquely combines rigorous logical frameworks with sociological analysis, particularly through the application of logical semantics to organizational phenomena. This interdisciplinary approach has enabled him to develop formal theories of social forms, organizational inertia, and institutional change. His publication record reveals a consistent trajectory from early work in logical semantics toward increasingly sophisticated applications in organizational theory. The most recent articles demonstrate his continued leadership in developing formal models of organizational phenomena, particularly in organizational ecology, structural inertia, and the mathematical foundations of sociological theory. His collaborations with leading scholars like Michael T. Hannan have produced influential theoretical frameworks that bridge disciplines. Best textbook Award from Ministry of Education (1987) Ministerial Award for Teaching Achievements (1988) Széchenyi Professzori Stipend of Applied Logic (1998) ERIM Fellowship (1999) Fellow, Netherlands Institute for Advance Study (2000) Best Paper in Mathematical Sociology Award (2003) Membership in European Academy of Sociology (2013) External Membership in Hungarian Academy of Science (2019) Professor Polos has supervised numerous doctoral students at Durham University and Erasmus Universiteit Rotterdam, with recent completions including Vladimir Vladimirov (2020) and Issam Al Tawari (2020). He has directed significant research initiatives including the Institute for Formal Studies in the Social Sciences (2000-2002), Research Centre CODES (2005-2016), and served as Work Package Leader and Principal Investigator of the COMPOSITE research project of the European Commission (2010-2014). From 2009-2017, he directed the Durham Doctoral Program DBA, and since 2020 has served as Co-Director of the Institute of Advanced Study at Durham University. His research is conducted through multiple collaborative frameworks including the Applied Logic Laboratory (ALL), Institute for Formal Studies in the Social Sciences, Center for Computer Science in Organization and Management (CCSOM), Erasmus Research Institute of Management (ERIM), Netherlands Institute for Advanced Study (NIAS), Center of Organizational Dynamics (CODES), and the Comparative Police Studies in the EU (COMPOSITE) project.

• Materials Simulation
• Density Functional Theory
• van der Waals Interactions
• +۷ مورد دیگر

T. Thonhauser is the Wright Family Professor of Physics and Associate Chair in the Department of Physics at Wake Forest University, where he also serves as Director of the Center for Functional Materials. He holds a Ph.D. in Physics from Karl-Franzens-Universität, Austria, and has built a distinguished career in computational materials science. His research focuses on advanced materials simulation, particularly in the development and application of van der Waals density functionals, metal-organic frameworks (MOFs), and nanomaterials for energy storage and gas separation. He leads the Materials Simulation Group, which combines theoretical modeling with experimental collaboration to design functional materials with tailored properties. His recent publications reveal a strong trend in designing MOFs for selective hydrocarbon separation, CO2 capture under humid conditions, and novel carbon allotropes. His work frequently appears in high-impact journals such as Nature Communications , JACS , and Physical Review B , reflecting his influence in the field of applied physics and materials chemistry. APS Fellow Simons Fellow KITP Scholar Ranlet and Frank Bell Jr. Fellow Wright Family Professor in Physics Endowed Chair Excellence in Teaching Award (2023) Advised Goldwater Scholar and NSF GRFP recipients Thonhauser actively mentors graduate and undergraduate students, including Noah Meyer, Trevor Jenkins, and Haardik Pandey. He has led significant research initiatives, including the founding of the Center for Functional Materials. His collaborative network spans institutions like MIT, Rutgers, and ORNL, emphasizing interdisciplinary research in energy and materials science. The Materials Simulation Group investigates porous materials for industrial gas separation, hydrogen storage, and environmental applications, with a strong emphasis on computational modeling and theoretical innovation in density functional theory.

• Natural Language Processing
• Human-Computer Interaction
• Speech Recognition
• +۱۳ مورد دیگر

Prof. Dr. Bernd Ludwig is a faculty member at the Institute for Information and Media, Language and Culture (I:IMSK) within the Faculty of Languages, Literature and Cultural Studies at the University of Regensburg. He has held the Professorship for Information Linguistics since August 2011, following a visiting role in the summer semester of that year. His academic journey began at Friedrich-Alexander-Universität Erlangen-Nürnberg, where he earned his PhD in 2004 and completed his habilitation in 2010. His research spans the interdisciplinary domains of natural language processing, human-computer interaction, and artificial intelligence, with a focus on spoken dialogue systems, user modeling, and context-aware assistive technologies. He leads projects like URWalking and ROSE, contributing to advancements in indoor navigation and intelligent mobile assistance. His recent publications reflect a diverse portfolio, combining AI and NLP with health informatics, social media analysis, and industrial applications. Trends show a growing emphasis on large language models, health recommendation systems, and the societal impact of AI. Scientific Awards: Zeitschrift für Medizinische Physik (ZMP) Autorenpreis 2022 AMiner Most Influential Scholar Award 2018 Nomination for Best Paper Award at MUM 2016 Nomination for Best Paper Award at KI 2010 SEW-EURODRIVE-Stiftung Studienpreis for Diploma Thesis (1997) Advising and Grants: Prof. Ludwig has supervised multiple doctoral candidates to completion, including Dr. Karema Al Subari and Dr. Robert Jackermeier, and currently mentors PhD students. He has secured research funding, notably a BMBF grant for the OPTAPEB project (2018–2021), and contributes to academic service as co-editor of Künstliche Intelligenz and organizer of major conferences such as CHIIR 2022 and COSIT 2019. Labs and Teams: He is a core member of the research team at the University of Regensburg, collaborating closely with Prof. Udo Kruschwitz, Prof. David Elsweiler, and others. His workgroup focuses on intelligent user interfaces, multimodal interaction, and practical applications of AI in everyday contexts.

Dennis James Williamsمشاهده پروفایل

استاد

• Transfusion Medicine
• Blood Banking
• Transfusion Safety
• +۷ مورد دیگر

Dennis James Williams, MD, is a Professor in the Department of Pathology and Laboratory Medicine at the University of Kentucky College of Medicine. He serves as Medical Director of the Transfusion Medicine Service and the Kentucky Blood Center, demonstrating leadership in clinical operations and blood safety. His work bridges academic medicine and practical transfusion services. Dr. Williams received his MD from Indiana University and completed his residency in Anatomic and Clinical Pathology at Ball Memorial Hospital, followed by a fellowship in Transfusion Medicine at the University of Cincinnati. His training provides a strong foundation in both laboratory medicine and clinical pathology. His research focuses on transfusion medicine, particularly the immunological effects of blood products, transfusion-related complications like TRALI and DIC, and strategies to improve transfusion safety. He has investigated how blood processing affects immune function and explored rapid diagnostic tools for infectious agents such as Zika virus. His work combines clinical insight with laboratory investigation to enhance patient outcomes. The recent publications show a consistent focus on transfusion immunology, emergency blood use, and diagnostic innovation. Themes include immune modulation by stored blood, point-of-care testing, and mitigation of transfusion-related adverse events. His research contributes significantly to evidence-based practices in blood banking. Experience with uncrossmatched blood in emergency settings Development of field-deployable Zika virus detection Studies on T-cell suppression due to transfusion TRALI reduction strategies in platelet collections Comprehensive reviews on DIC Dr. Williams has not listed any formal scientific awards in the provided text. However, his leadership roles and scholarly output indicate recognition within the field of transfusion medicine. There is no mention of student advising or grant funding in the available information. His contributions are primarily through clinical leadership, research publications, and service as Medical Director in key blood banking institutions. While specific laboratory or research teams are not detailed, his collaborative publications suggest active engagement with multidisciplinary teams in trauma, infectious disease, and immunology research. His role at the Kentucky Blood Center implies oversight of operational and research aspects of blood donation and distribution.

Jessica Borgerمشاهده پروفایل

دانشیار

• Immunology
• T-cell Biology
• Translational Medicine
• +۹ مورد دیگر

Associate Professor Jessica Borger is a faculty member at the School of Translational Medicine, Monash University, where she currently serves as the Director of Education. She previously held roles as Lecturer and Graduate Course Convenor, establishing a Master's program in Translational Research and Medicine. She also held leadership positions at the Walter and Eliza Hall Institute (WEHI) and the University of Melbourne as Scientific Education Team Leader and Graduate Research Coordinator. University: Monash University School: School of Translational Medicine Academic Rank: Associate Professor Email: jessica.borger@monash.edu Education: Bachelor of Medical and Pharmaceutical Biotechnology (Honours), University of South Australia PhD (Medical Research Council Scholarship), National Institute of Medical Research, awarded through University College London Research Interests: Jessica Borger’s research spans immunology and translational medicine, with a focus on T-cell biology. Her work investigates novel CAR-T cell therapies for lung diseases using intracellular checkpoint blockade and explores the signaling pathways of unconventional T cells in pulmonary inflammation. She also conducts impactful research in science education, equity, and inclusion in STEMM, advocating for gender balance and systemic reform in medical research. Recent Publications Trend: Her recent scholarly output reveals a dual trajectory: cutting-edge immunological research in T-cell mechanisms and pulmonary disease, alongside influential contributions to equity in science, education policy, and gender representation in research funding. These works appear in high-impact journals such as EBioMedicine , Immunology and Cell Biology , and public platforms like The Conversation. Scientific Awards: Veski Inspiring Women STEM Scholarship (mid-career) Margaret Baird Women in Immunology Award (2019) Cheers-Buchan Education Award (2024) Multiple Dean’s and Vice-Chancellor’s Awards for Excellence in Education and Diversity & Inclusion (2021) Best Postdoctoral Speaker and Presentation Awards (2017–2018) AMREP EMCR Collaborative Seed Grant (2018) Cass Foundation International Travel Award (2018) Advising and Grants: While specific student names are not listed, Dr. Borger has served as Graduate Course Convenor and Graduate Research Coordinator, indicating extensive mentoring experience. She led the 'Designing superior killers in cancer immunotherapy' research project as Primary Chief Investigator (2019) and received the CASS Foundation Medicine/Science grant for her CAR-T therapy research. Her editorial and advisory roles further reflect leadership in academic development and policy. Labs and Teams: Dr. Borger leads research in immunology and translational medicine at Monash University. Her work involves collaboration with key researchers such as Prof. Michael Hibbs and Prof. Dale Godfrey. She contributes to national and international networks through her roles in the Australian and New Zealand Society for Immunology (ASI), the International Union of Immunological Societies (IUIS) Gender Equality Committee, and editorial boards for Immunology & Cell Biology and BAMBED .

• Structural Biology
• Immunology
• Malaria
• +۷ مورد دیگر

Dene Littler is a Research Fellow in the Department of Biochemistry & Molecular Biology at Monash University, where he conducts cutting-edge research at the intersection of structural biology, immunology, and infectious diseases. His work significantly contributes to understanding immune responses in malaria, influenza, and SARS-CoV-2, particularly focusing on antigen presentation and T-cell epitope recognition. His research interests span Structural Biology , Immunology , Malaria , Viral Immunology , Computational Biology , and Antigen Processing . He employs advanced techniques in structural analysis and bioinformatics to investigate molecular mechanisms in pathogen-host interactions. A major focus is on the PTEX-dependent protein export system in Plasmodium falciparum and the immunopeptidome of viral antigens. The recent publications demonstrate a strong trend toward integrating machine learning with immunological data, particularly in predicting CD4+ and CD8+ T cell epitopes using contrastive and transfer learning models. These interdisciplinary studies are published in high-impact journals such as Nature Communications and Nature Machine Intelligence , reflecting the significance and innovation of his research. Dene Littler collaborates extensively with leading immunologists including James Rossjohn, Anthony Purcell, Katherine Kedzierska, and Nicole Mifsud. These collaborations span structural immunology, viral immunity, and systems biology, enhancing the translational potential of his work. Although no formal students or awards are listed, his role as a key contributor in multiple high-impact studies underscores his scientific influence. He is actively involved in research with ongoing outputs through 2025, indicating sustained productivity and engagement in major projects related to global health challenges, including those aligned with UN Sustainable Development Goals on health and well-being.

• Climate Statistics
• Extreme Weather Modeling
• Atmospheric Science
• +۵ مورد دیگر

T. Economou is affiliated with the Department of Mathematics and Computer Science at the University of Exeter, UK, where he conducts research at the intersection of statistics and meteorology. His work primarily focuses on modeling extreme weather events, particularly the serial clustering of extratropical cyclones, using climate model outputs and statistical methodologies. His research interests lie in climate statistics , spatio-temporal modeling , and extreme event analysis , with applications to atmospheric dynamics and climate change impacts. He applies advanced statistical techniques to understand patterns in storm occurrences and their variability under changing climate conditions. The two available publications show a strong trend in analyzing extreme meteorological phenomena through rigorous statistical frameworks. His work emphasizes quantifying uncertainty, modeling dispersion in storm counts, and assessing the role of large-scale climate drivers such as the North Atlantic Oscillation. These studies contribute to improving risk assessments related to clustered extreme weather events in Europe and the North Atlantic region. Scientific Awards: No awards mentioned in the provided text. Advising and Grants: There is no information available regarding students advised or grants received. However, his active involvement in CMIP5-based research suggests potential participation in collaborative, funded climate science initiatives. Labs and Teams: While no formal lab or team structure is described, T. Economou collaborates with researchers from institutions such as the University of Reading and the University of Cologne, particularly within the context of multi-model climate analysis and extratropical cyclone dynamics.

Claire Jessupمشاهده پروفایل

مدرس ارشد

• Immunology
• Cancer Immunotherapy
• Autoimmune Diseases
• +۵ مورد دیگر

Dr Claire Jessup is a Senior Lecturer at Flinders University's College of Medicine and Public Health, where she serves as a Full Member of the Flinders Health and Medical Research Institute. She heads the Immunomodulation (iMOD) Laboratory, focusing on harnessing the immune system to modulate disease processes. Dr Jessup holds a PhD from Flinders University (awarded December 2005) and completed an NHMRC CJ Martin Overseas Biomedical Postdoctoral Fellowship at Oxford University in 2006. She also maintains an adjunct position as Senior Lecturer at the University of Adelaide since 2012. Her research program centers on immune modulation of complex cellular interactions in diabetes development, transplant rejection, and oncogenesis. Dr Jessup's laboratory utilizes advanced techniques including flow cytometry, gene therapy, pancreatic islet isolation, immune assays, confocal microscopy, and islet transplantation models. Her work has demonstrated the potential of cellular cotherapy using endothelial progenitor cells to improve islet transplantation outcomes. Current projects investigate the interplay between tissue microenvironment, vasculature, and the immune system, with applications for clinical immunomodulation. Dr Jessup's recent publications reveal a strong focus on immune receptor signaling, pancreatic cancer microenvironment, islet cell biology, and serotonin regulation in the gut. Her work spans immunology, diabetes research, oncology, and neurogastroenterology, demonstrating interdisciplinary approaches to complex biological problems. Her scientific achievements have been recognized with numerous awards including: ASI Breakthrough Immunology Award (2022) Tim Welborn Mid-career Basic Researcher Fellowship from JDRF Australia (2024) Innovative Grant Award from JDRF International (2022) Vice Chancellor's Award for Early Career Researchers (2012) South Australian Young Tall Poppy Science Award (2011) Dr Jessup actively supervises PhD students and has successfully guided Ms Amy Hughes (PhD Dean's Commendation, 2013) and Ms Darling Rojas (Thomas E. Starzl Postdoctoral Fellowship, 2011). She also provides associate supervision for projects on dendritic cells and gene therapy related to pancreatic islets. Her research is supported by major funding bodies including JDRF Australia, NHMRC, Diabetes Australia, Channel 7 Children's Research Foundation, FMC Foundation, and the Department of Further Education, Employment, Science and Technology. As leader of the Immunomodulation Laboratory, Dr Jessup directs a research team investigating molecular activation of immune cells in cancer treatment and autoimmune diseases. Her laboratory's work on T lymphocyte activation during Type 1 diabetes, checkpoint inhibitors for cancer immunotherapy, and vascular-endocrine cell interplay during islet transplantation represents cutting-edge research in immunomodulation.

• Body Image
• Eating Disorders
• Co-Design Methodology
• +۳ مورد دیگر

Mia Pellizzer is a Research Fellow and Lecturer in Psychology at Flinders University's College of Education, Psychology and Social Work. She serves as Placement Coordinator for postgraduate psychology students and Topic Coordinator for PSYC9014 Introduction to Cognitive Behavioural Therapy. Her research focuses on body image disturbances across clinical populations, including those with inflammatory bowel disease, eating disorders, endometriosis, and peripartum women. Mia's work emphasizes co-design methodologies, integrating lived experience perspectives into intervention development. She contributes to the Flinders University Institute for Mental Health and Wellbeing and collaborates with Professor Tracey Wade on NHMRC-funded projects targeting youth mental health. Eating Disorders Body Image Research Co-Design with Lived Experience Clinical Psychology Practice Qualitative Methodology Health Psychology Applications Her recent publications explore transdiagnostic approaches to eating disorders, body image in chronic illnesses, and digital mental health interventions. Awards include the ANZAED Peter Beumont Young Investigator Award (2018) and the Flinders University Medal (2015). Mia supervises postgraduate psychology students and actively participates in curriculum development, guest lecturing on family-based therapy and multidisciplinary teamwork. She serves on the ANZAED Professional Development Strategy Committee and reviews for journals including the International Journal of Eating Disorders.

• Speech and Hearing
• Acoustic Engineering
• Middle Ear Physiology
• +۳ مورد دیگر

Susan Voss is the Achilles Professor of Engineering at the Picker Engineering Program, Smith College, where she has been a faculty member since January 2001. She teaches courses including Introduction to Engineering: Energy and the Environment, Circuit Theory, Signals and Systems, and Acoustics. Her research spans electrical engineering and auditory science, with a primary focus on sound transmission in normal and diseased ears and applications in audiometric instrumentation and auditory implants. Dr. Voss received her B.S. in Engineering from Brown University (1991), M.S. from MIT's Department of Electrical Engineering and Computer Science (1995), and Ph.D. from the Harvard-MIT Division of Health Sciences and Technology (1998). Her research interests include: Wideband acoustic immittance (WAI) measurements and database development Ear canal geometry and its relationship to age Noninvasive diagnostic tools for middle-ear problems Applications of acoustic measurements in hearing assessment Development of monitoring tools for intracranial pressure Dr. Voss's publication record demonstrates consistent progression from fundamental acoustic principles to clinical applications, with increasing emphasis on creating standardized databases and measurement protocols. Her recent work focuses on population studies of ear acoustics, geometric modeling of ear canals, and developing non-invasive monitoring techniques with NASA collaboration. Her significant contributions have been recognized through: R15 AREA grant from NIH (2014-2024) for "Development of a normative database for wide-band acoustic immittance measures" NSF CAREER AWARD for "Acoustic Energy Flow Through Normal and Abnormal Middle Ears" Tau Beta Pi National Laureate Award Frontiers in Education New Faculty Fellow AT&T Graduate Research Program for Women Grant Young Investigator Talk at the 2013 American Auditory Society Meeting Dr. Voss actively supervises student research and has developed an online WAI database to facilitate research collaboration. She collaborates on NASA-funded projects to develop noninvasive tools for monitoring intracranial pressure using auditory responses, demonstrating the translational impact of her engineering research.

Jennifer Quiziمشاهده پروفایل

استاد مدعو

• Biomanufacturing
• Viral Therapy
• Gene Therapy
• +۶ مورد دیگر

Jennifer Quizi, PhD , is an Adjunct Professor in the Department of Biochemistry, Microbiology and Immunology at the Faculty of Medicine, University of Ottawa . She is affiliated with the Ottawa Hospital Research Institute (OHRI) and leads the BMC VMF Group as a contract development and manufacturing organization . Specializes in GMP-compliant manufacturing of virus-based therapies Focuses on process innovation to reduce biologics costs Director of CanPRIME , Canada’s first hands-on biomanufacturing training program Research Interests revolve around biologics manufacturing , viral vector development , and training next-generation biomanufacturing professionals . Her work addresses challenges in affordable access to therapeutic viruses and innovations in GMP processes , including customized cell lines to maximize yields. Her publications highlight advancements in CAR-T cell trials , autologous vaccine production , and integrated training models . The CanPRIME program she co-develops trains 5 co-op students annually from University of Ottawa , Carleton University , and Algonquin College . Team Composition : 35 full-time experts in process development, quality control, and project management, supported by 5 CanPRIME trainees during May-December.

Marc Bitoun and Stéphane Vassilopoulosمشاهده پروفایل

استاد

• Muscle Cell Biology
• Neuromuscular Diseases
• Centronuclear Myopathy
• +۶ مورد دیگر

Marc Bitoun and Stéphane Vassilopoulos are INSERM Research Directors who co-lead a research team focused on muscle cell organization and therapy of autosomal dominant centronuclear myopathy at the Institute of Myology. Their collaborative work bridges fundamental muscle biology with therapeutic development for neuromuscular diseases, particularly those involving Dynamin 2 (DNM2) mutations. Their research interests encompass muscle cell biology , endocytosis and autophagy mechanisms , mechanotransduction , and gene therapy development for neuromuscular disorders. They investigate how fundamental cellular processes like endocytosis, autophagy, and mechanical stress response contribute to muscle homeostasis and disease pathogenesis, with particular focus on centronuclear myopathy and related conditions. Analysis of their recent publications reveals a strong trend toward translational research , with increasing focus on therapeutic development including AAV vector optimization, allele-specific silencing therapies, and pharmacological interventions. Their work spans from basic cellular mechanisms to preclinical therapeutic validation, with particular emphasis on how cellular machinery can be harnessed for therapeutic purposes. Patent EP22306213.4 for Allele-specific siRNA therapy for Dynamin 2-related diseases Patent PCT/EP2017/080884 for Allele-specific silencing therapy for Dynamin 2-related disorders They mentor a substantial research team including doctoral students, post-doctoral fellows, and research engineers. Their work involves multiple collaborative projects examining cellular mechanisms in muscle physiology and pathology, with particular emphasis on developing therapies for centronuclear myopathy and optimizing AAV-based treatments for neuromuscular diseases. Their laboratory investigates the cellular and molecular mechanisms involved in muscle function under both physiological and pathological conditions, with applications to therapeutic development.

• Pancreatic ductal adenocarcinoma
• Lung adenocarcinoma
• RNA splicing
• +۷ مورد دیگر

Luisa Escobar-Hoyos is an Assistant Professor of Therapeutic Radiology at Yale School of Medicine, with secondary appointments in Medical Oncology and Hematology and Molecular Biophysics and Biochemistry. She serves as Director of Department Cores and Radiobiology Course Director in the Department of Therapeutic Radiology. Dr. Escobar-Hoyos obtained her master's degree in Biomedical Sciences at the Universidad del Valle in Cali, Colombia, followed by a Ph.D. in Cancer Molecular and Cellular Pharmacology at Stony Brook University as a Fulbright Scholar. She completed her postdoctoral training at Memorial Sloan Kettering Cancer Center under the mentorship of Drs. Steven Leach and Omar Abdel-Wahab. Her research focuses on understanding and targeting somatic mutations and aberrant RNA processing in pancreatic and lung cancers to develop novel therapies. Dr. Escobar-Hoyos' lab investigates how activating mutations in KRAS and p53 cooperate to cause tumors, with a particular focus on how altered RNA splicing by mutant p53 activates and maintains oncogenic KRAS signaling. Her team has developed a novel therapy called Splicing-Hit Oligonucleotide Therapy (SHOT) that corrects RNA splicing errors to selectively kill pancreatic and lung cancer cells. Dr. Escobar-Hoyos' work spans cancer biology, RNA splicing, tumor immunology, and genetically engineered mouse models. Her research has revealed that keratin 17 serves as a prognostic and predictive biomarker in pancreatic ductal adenocarcinoma and non-small cell lung cancer, and modulates the immune topography of pancreatic tumors. Damon Runyon-Rachleff Innovation Award (2023) from Damon Runyon Cancer Research Foundation Career Development Award to Further Diversity, Equity, and Inclusion (2022) from American Association for Cancer Research Dr. Escobar-Hoyos leads a collaborative research team that includes postdoctoral associates, graduate students, and research scientists. Her laboratory collaborates with researchers at Yale University, Stony Brook University, and Memorial Sloan Kettering Cancer Center across disciplines including oncology, immunology, bioinformatics, drug delivery, and microbiology. She also directs the Escobar-Hoyos Lab, which focuses on developing innovative therapies for pancreatic and lung cancers.