جست‌وجوی استاد و پژوهشگر

• Skeletal Muscle Growth
• Ribosome Biogenesis
• Exercise Physiology
• +۴ مورد دیگر

Gustavo Nader, Ph.D., is a Professor of Kinesiology at The Pennsylvania State University's College of Health and Human Development, where he holds the Dorothy Foehr Huck and J. Loyd Huck Endowed Chair in Molecular, Cellular and Integrative Physiology. His research laboratory at 101 Noll Lab focuses on molecular mechanisms of skeletal muscle adaptation, employing human, animal, and cellular models to investigate ribosome biogenesis, transcriptional regulation, and muscle growth control in contexts ranging from exercise hypertrophy to cancer cachexia. Dr. Nader's research examines fundamental processes including: Ribosome biogenesis and its role in muscle growth regulation Epigenetic control of RNA Polymerase I activity Molecular pathways in mechanical overload-induced hypertrophy Tumor-induced muscle wasting mechanisms Biomimicry approaches inspired by hibernator physiology His work spans exercise physiology, cancer biology, and environmental stress responses. Analysis of his 15 most recent publications (2015-2025) reveals predominant themes in muscle hypertrophy mechanisms, cancer cachexia pathophysiology, ribosomal function analysis, and environmental stress impacts on muscle. His work consistently integrates molecular techniques with physiological models across species. Notable scientific recognitions include: Dorothy Foehr Huck and J. Loyd Huck Chair appointment (2024) Huck Institutes Leadership Fellowship (2025-2026) Dr. Nader leads an active research team investigating muscle plasticity, with current projects funded through the Huck Institutes of the Life Sciences. He collaborates extensively through Penn State's Integrative and Biomedical Physiology graduate program and Center for Cellular Dynamics.

Eduardo N. Chiniمشاهده پروفایل

استاد

• Metabolism
• NAD Metabolism
• Aging
• +۱۱ مورد دیگر

Eduardo N. Chini, M.D., Ph.D., is a Professor at Mayo Clinic with primary and joint appointments in the Department of Anesthesiology and Perioperative Medicine and the Department of Cancer Biology. He is based in Rochester, Minnesota, and leads a research program focused on NAD metabolism, aging, and their roles in diseases such as cancer, obesity, and kidney disease. Education: BS in Biology, Centro Educacional de Niteroi-RJ MD, Universidade do Rio de Janeiro PhD in Biological Chemistry, Universidade do Rio de Janeiro Fellow, Department of Physiology and Biophysics, Mayo Clinic Resident in Anesthesiology, Mayo Clinic College of Medicine Research Interests: Eduardo N. Chini's research investigates the central role of nicotinamide adenine dinucleotide (NAD) in cellular metabolism, aging, and disease. His lab has made foundational discoveries in NAD catabolism, identifying CD38 as the primary enzyme regulating NAD levels in mammals. His work explores SIRT1 regulation via CD38 and DBC1, NAD metabolism in cancer, and its implications in polycystic kidney disease. He is particularly interested in how NAD signaling influences aging, metabolic syndrome, and organ dysfunction. Recent Research Trends: His recent publications (2023–2025) reveal a strong focus on the role of CD38 in aging, immune function, and tissue metabolism. Key themes include NAD+ depletion triggering inflammatory responses, CD38 inhibition as a therapeutic strategy for cardiotoxicity and metabolic aging, and the interplay between senescence, stem cell function, and mitochondrial health. His work increasingly integrates translational models with molecular mechanisms in aging and cancer. Scientific Awards: Florida Investigator of the Year, Mayo Clinic (2024) Glenn/AFAR Breakthroughs in Gerontology Award (2007) Edward C. Kendall Award, Mayo Clinic Alumni Association (2002) Directors Award for Aging Research, Kogod Center on Aging (2018) Distinguished Scientist Seminar Series, Georgetown Medical School (2022) Grants and Leadership: Dr. Chini is a co-Principal Investigator on multiple NIH-funded grants, including projects on CD38 in scleroderma, CLL, and male reproductive aging. He is Co-Director of the Mayo Clinic Mitochondrial Care Center and Associate Director of the Robert and Arlene Kogod Center on Aging. He has served on numerous national review panels and advisory councils, including the NIH Hepatobiliary Pathophysiology Study Section and AFAR's National Scientific Advisory Council. Labs and Teams: Dr. Chini leads a research laboratory at Mayo Clinic focused on NAD metabolism and aging. His team collaborates extensively with experts in cancer biology, mitochondrial medicine, and aging research. He is affiliated with the Mayo Clinic Comprehensive Cancer Center, the Kogod Center on Aging, and the Robert M. and Billie Kelley Pirnie Translational PKD Center.

• Skeletal Muscle Physiology
• Ribosome Biogenesis
• Transcriptional Regulation
• +۴ مورد دیگر

Gustavo Alberto Nader is a Professor of Kinesiology at The Pennsylvania State University , holding the Dorothy Foher and J. Lloyd Huck Chair in Molecular, Cellular and Integrative Physiology. His research focuses on skeletal muscle growth control , ribosome biogenesis , and transcriptional/epigenetic regulation in health and disease contexts. Affiliated with the Huck Institutes of the Life Sciences and College of Health and Human Development Principal Investigator on NIH-funded projects examining ribosomal control of muscle mass Research Interests span molecular mechanisms of muscle adaptation to exercise, cancer cachexia, chronic disease impacts on muscle, and cross-species Wnt signaling regulation by CO₂ levels. Key methodologies include human/animal/cell models, ribosomal analysis, and epigenetic profiling. Publication Trends show sustained focus on: Ribosome biogenesis in muscle hypertrophy (2012–2025) Cancer-induced muscle wasting mechanisms (2015–2024) CO₂/Wnt pathway interactions (2015–2019) Exercise-induced transcriptional responses (2001–2016) Scientific Awards include the Huck Chair, while his Grants & Collaborations involve NIH-funded studies on transcriptional/epigenetic mechanisms (2019–2026) with cross-disciplinary teams in physiology, oncology, and respiratory medicine.

David N. Proctorمشاهده پروفایل

استاد

• Aging
• Cardiovascular Physiology
• Exercise Physiology
• +۵ مورد دیگر

David N. Proctor is a Professor of Kinesiology and Physiology at Pennsylvania State University . His research focuses on human cardiovascular aging, vascular adaptation to exercise, and therapeutic strategies for aging populations.

Jingsong Zhouمشاهده پروفایل

استاد

• Neuromuscular Diseases
• Striated Muscle Physiology
• Calcium Signaling
• +۴ مورد دیگر

Dr. Jingsong Zhou is a Professor of Kinesiology and Associate Director of the Bone-Muscle Research Center at The University of Texas at Arlington. Her research focuses on neuromuscular diseases, particularly Amyotrophic Lateral Sclerosis (ALS), with expertise in striated muscle physiology, calcium signaling, and mitochondrial dysfunction. She leads the Neuromuscular Diseases Lab, which develops genetic mouse models and molecular probes to study ALS mechanisms. Dr. Zhou’s work has been supported by NIH, MDA, DOD, and the ALS Association. She serves on the NIH SMEP study section and has over 20 years of academic experience, including postdoctoral training at Vanderbilt University College of Medicine and a PhD from Rush University School of Medicine. Education: Postdoctoral Fellow in Pharmacology, Vanderbilt University College of Medicine (2001) PhD in Molecular Biophysics and Physiology, Rush University School of Medicine (1997) Diploma in Medicine, Hunan Medical University (Xiangya Medical School) (1986) Research Interests: Mechanisms of calcium signaling and mitochondrial dysfunction in ALS Role of sarcolemma repair and autophagy in neuromuscular disease progression Development of therapeutic strategies targeting mitochondrial health and membrane integrity Grants and Funding: NIH grants focused on ALS pathogenesis and muscle-bone interactions Support from MDA, DOD, and ALS Association for translational research projects Labs and Teams: Director of the Neuromuscular Diseases Lab at UT Arlington Collaborations in developing mouse models and molecular tools for ALS research

Katrien De Bockمشاهده پروفایل

استاد

• Muscle Microenvironment
• Angiogenesis
• Metabolic Crosstalk
• +۴ مورد دیگر

Prof. Dr. Katrien De Bock is a Full Professor and Deputy Head of the Department of Health Sciences and Technology at ETH Zurich. Her research focuses on angiogenesis, metabolic crosstalk in muscle microenvironments, and the impact of exercise on muscle regeneration. She leads a team investigating cellular interactions in skeletal muscle, particularly how metabolic signals regulate blood vessel growth and muscle repair. Key areas include understanding fibroadipogenic progenitors' role in muscle physiology, the role of histamine in exercise responses, and age-related muscle decline. Her work integrates molecular biology, single-cell transcriptomics, and computational approaches to dissect mechanisms underlying tendon pathologies, ischemic muscle injury, and metabolic adaptations to exercise. She supervises Master's programs in Human Movement Science and collaborates on projects involving muscle stem cell therapies and vascular engineering. Prof. De Bock also explores interventions like NAD+ precursors to counteract age-related sarcopenia and promotes translational research in regenerative medicine. Research Interests: Exercise-induced metabolic pathways in muscle repair Angiogenesis regulation in health and disease Hypoxia signaling in tendons and muscles Epigenetic modifications during tissue regeneration Stem cell fate determination in muscle microenvironments Notable Projects: Developing AI-driven histologic analysis for tendinopathy diagnosis Mapping the human brain vasculature at single-cell resolution Testing sulfur amino acid restriction to enhance exercise capacity

Young Sub Kwonمشاهده پروفایل

استاد

• Exercise Physiology
• High-Intensity Exercise
• Thermoregulation in Exercise
• +۳ مورد دیگر

Dr. Young Sub Kwon is a Full Professor in the Department of Kinesiology at Cal Poly Humboldt, affiliated with the School of Applied Health. His research focuses on temperature regulation in high-intensity exercise physiology, virtual exercise laboratories, and fitness assessments for first responders. He holds a Ph.D. in Sports & Exercise Science from the University of New Mexico and has pioneered studies on cooling technologies for military and athletic applications, widely covered by major media outlets like NBC and the Wall Street Journal. Dr. Kwon teaches graduate courses including Exercise Testing and Physiology of Exercise. He has developed innovative virtual labs to enhance accessibility in exercise science education and co-authored a textbook on Exercise Physiology. His work includes collaborations with local fire departments and law enforcement to create fitness programs, involving over 20 students in research projects. Over 30 peer-reviewed publications and presentations at international conferences highlight his contributions to firefighter fitness, HIIT optimization, and thermal physiology. He has secured grants including the CSU Faculty-Student Collaborative Research Grant and led projects funded by the College of Professional Studies. His teaching philosophy emphasizes critical thinking, hands-on lab experiences, and student support through certification exam preparation. Dr. Kwon actively mentors students, fostering their academic and professional growth in kinesiology.

John G Georgiadisمشاهده پروفایل

استاد

• Biomedical Engineering
• Magnetic Resonance Imaging (MRI)
• Biomechanics
• +۳ مورد دیگر

John G Georgiadis is the Interim Chair and R. A. Pritzker Professor of Biomedical Engineering at Illinois Institute of Technology's Armour College of Engineering. He holds affiliations with the Illinois Tech Digital Medical Engineering and Technology (IDMET) Research and Education Center. His academic journey includes a Ph.D. (1987) and M.S. (1984) in Mechanical Engineering from UCLA, and a Diploma in Mechanical Engineering from the National Technical University of Athens (1983). Georgiadis’ research focuses on aging-related changes in the brain and skeletal muscle, leveraging MRI and computational models. Key projects include intramyocellular biotransport, cerebral microvasculature imaging, and multiscale brain mechanics. He has pioneered advancements in magnetic resonance elastography (MRE) for non-invasive tissue stiffness measurement, contributing to clinical applications in neurology and cardiology. His awards include the NSF Presidential Young Investigator Award (1991–1997) and Fellow status in the American Institute for Medical and Biological Engineering. Georgiadis has authored over 150 peer-reviewed publications and holds multiple patents in medical device technology and imaging techniques. His work bridges biomechanical engineering, computational imaging, and clinical diagnostics, with implications for aging populations and chronic disease management. Professional memberships include the Biomedical Engineering Society, IEEE, and AIMBE. His labs focus on translational research, integrating advanced imaging modalities with biomechanical principles to address complex biomedical challenges.

Natalia Imad Khalafمشاهده پروفایل

استادیار

• Pancreatic Cancer
• Gastroenterology
• Epidemiology
• +۳ مورد دیگر

Natalia Imad Khalaf, MD, MPH, FACP is an Assistant Professor in the Department of Medicine at Baylor College of Medicine with dual appointments as Clinical Investigator in the Clinical Effectiveness and Population Health Program and Core Faculty in the Health Policy, Quality & Informatics Program at the Center for Innovations in Quality, Effectiveness and Safety (IQuESt) at Michael E. DeBakey VA Medical Center. Her academic trajectory spans clinical gastroenterology, epidemiology, and health services research with focus on cancer outcomes. Her educational foundation includes: BA in Biological Sciences from Rice University (2007) MD from Baylor College of Medicine (2011) Internal Medicine Residency and Chief Medical Residency at Baylor College of Medicine (2014-2015) Gastroenterology & Hepatology Fellowship at Brigham and Women's Hospital (2018) MPH in Epidemiology from Harvard T.H. Chan School of Public Health (2018) Dr. Khalaf's research program centers on pancreatic cancer epidemiology, with emphasis on early detection biomarkers (particularly new-onset diabetes), metabolic risk factors, and healthcare system interventions. Her work integrates clinical gastroenterology with population health methodologies to address diagnostic delays, racial disparities in treatment, and implementation of evidence-based guidelines in gastrointestinal cancers. She actively develops risk prediction tools using health informatics and deep learning approaches. Analysis of her recent publications reveals a concentrated focus on pancreatic cancer pathophysiology and outcomes, with significant contributions to understanding pre-diagnostic metabolic changes, emergency presentation consequences, and diabetes-cancer linkages. Her colorectal cancer work examines screening adherence barriers and medication risk associations, while quality improvement research targets guideline implementation for gastric intestinal metaplasia. Her scientific recognition includes: AGA Academy of Educators Elected Member (2018) Bob Parsons Inaugural Fellow in Pancreatic Cancer Research (2017-2018) American Gastroenterological Association Early Career Investigator Recognition (2017) Soma Weiss Award for Clinical Teaching Excellence (2017) Dean of Medical Education Outstanding Resident Teacher Award (2013) Phi Beta Kappa Honor Society (2007) Dr. Khalaf directs multiple federally funded research initiatives including: VA Career Development Award: Health Informatics Approaches to Improve Early Diagnosis of Pancreatic Cancer ($1.09M, 2022-2026) National Academy of Sciences: Clinical Quality Measures for Gastrointestinal Cancers (2022-2027) Gordon and Betty Moore Foundation: Implementing Digital Quality Measures (2024-2025) American Pancreatic Association Young Investigator Grant (2019-2021) She operates within the IQuESt research ecosystem at the Michael E. DeBakey VA, leveraging the Clinical Effectiveness and Population Health Program infrastructure for her work on cancer diagnostic excellence, veteran health outcomes, and implementation science projects targeting gastrointestinal cancer care pathways.

• Metabolic Health in Obesity
• Nonalcoholic Fatty Liver Disease (NAFLD)
• Hepatokine Research
• +۵ مورد دیگر

Prof. Norbert Stefan is a Full Professor at the University of Tübingen's Department of Internal Medicine IV, specializing in clinical and experimental diabetology. His work focuses on metabolic health in obesity, nonalcoholic fatty liver disease (NAFLD), and hepatokine research. Pioneered metabolic phenotyping studies in the Tübingen Lifestyle Intervention Program (TULIP) Conducted seminal NIH/NIDDK research on adiponectin's role in insulin resistance in Pima Indian populations Developed the concept of hepatokines in 2008 with his colleagues His 2025 publications span GLP-1 receptor agonists' effects on liver fibrosis, SGLT2 inhibitors' impact on liver events, and precision medicine approaches for metabolic dysfunction-associated steatotic liver disease. Current research integrates urinary peptidomics, brain insulin action studies, and advanced visceral fat quantification techniques. Scientific Awards Innovation Award of the German Society for University Medicine (2010) Heisenberg-Professorship for Clinical and Experimental Diabetology (2011) Editorial Board Member, The Lancet Diabetes & Endocrinology (2015) Senior Associate Editor, Diabetes (2021) Stefan maintains collaborative networks with Harvard Medical School, Boston Children's Hospital, the NIH, and consortia like SOPHIA IMI EU Consortium and the German Center for Diabetes Research.

Geoffrey Handsfieldمشاهده پروفایل

استادیار

• Biomedical Imaging
• Rehabilitation Engineering
• Musculoskeletal Biomechanics
• +۴ مورد دیگر

Geoffrey Handsfield is an Assistant Professor at the University of North Carolina at Chapel Hill, holding appointments in the Department of Orthopaedics and the Lampe Joint Department of Biomedical Engineering. His work integrates advanced medical imaging, computational modeling, and mechanical experimentation to improve clinical orthopaedic medicine and understand musculoskeletal form and function. Educated at East Carolina University (B.S. Physics, Summa Cum Laude with Mathematics Minor), the University of Virginia (Ph.D., Biomedical Engineering), and as a Whitaker Postdoctoral Scholar at the University of Auckland, his research focuses on musculoskeletal MRI, computational modeling of muscle-tendon interactions, and pediatric cerebral palsy rehabilitation. Education: Ph.D., Biomedical Engineering, University of Virginia, 2014 Postdoctoral Fellowship, Auckland Bioengineering Institute, 2014–2016 (Whitaker Scholar) B.S., Physics (Summa Cum Laude), Mathematics Minor, East Carolina University, 2008 Research Interests: Dr. Handsfield’s lab pioneers techniques like ultra-high contrast MRI and 3D ultrasound to study muscle-fascia interactions, tendon mechanics, and pediatric cerebral palsy. Key areas include: Image-based computational models for personalized musculoskeletal analysis Muscle architecture and regeneration in children and athletes Biomechanical interventions for cerebral palsy rehabilitation Non-invasive muscle profiling for clinical decision-making Awards: Aotearoa Early Career Research Fellow, Robertson Foundation Early Career Research Award, Australia-New Zealand Orthopaedic Research Society Whitaker Postdoctoral Scholar Academic All-American in Swimming & Diving (2007–2008) Advising & Grants: While specific grant details are not listed, his lab’s focus on pediatric cerebral palsy and musculoskeletal modeling suggests involvement in NIH-funded or foundation-sponsored research. No formal advisees are listed in the provided data. Labs & Teams: His interdisciplinary lab collaborates with clinicians and engineers to translate imaging and modeling innovations into clinical practice, focusing on tools like the dSIR MRI sequence and high-dimensional muscle clustering for athlete and pediatric populations.

Corey Tomczakمشاهده پروفایل

دانشیار

• Cardiovascular Physiology
• Cardiac Rehabilitation
• Heart Failure
• +۴ مورد دیگر

Dr. Corey Tomczak is an Associate Professor in the Department of Kinesiology at the University of Saskatchewan. His research focuses on cardiovascular physiology, cardiac rehabilitation, and exercise intolerance in chronic conditions such as heart failure and congenital heart disease. He holds a PhD in Rehabilitation Medicine and has extensive postdoctoral training in the field. His work integrates clinical and physiological approaches to improve outcomes in patients with cardiovascular disorders. Affiliations: University of Saskatchewan, College of Kinesiology Research Themes: Health Aging and Management of Chronic Conditions, Child and Youth Health and Development Dr. Tomczak's research examines mechanisms underlying exercise limitations in heart failure and congenital heart disease, including autonomic regulation, vascular function, and skeletal muscle metabolism. He has trained numerous graduate students and mentors future researchers in cardiovascular physiology. His lab, the Russ Kisby Physical Activity and Health Promotion Laboratory, collaborates with clinical partners at the Royal University Hospital. Key areas of investigation include cerebrovascular responses during exercise, muscle metaboreflex modulation of cardiac function, and the impact of exercise training on cardiovascular outcomes. Recent work highlights impaired vascular function in heart failure and sex-based differences in exercise capacity.

• Molecular Chaperones in Cancer
• Heat Shock Proteins (Hsp60, Hsp90, Hsp27)
• Thyroid Pathology
• +۵ مورد دیگر

Francesca Rappa is a Full Professor in the Department of Human Anatomy and Histology within the School of Medicine and Surgery at the University of Palermo. Her academic position (BIOS-12/A classification) centers on biomedicine, neuroscience, and advanced diagnostics with a focus on molecular mechanisms of disease. Her research spans multiple interconnected domains centered on stress response systems. Key interests include: Molecular chaperone networks (particularly Hsp60, Hsp90, Hsp27) in carcinogenesis Thyroid and colorectal cancer pathophysiology Glioblastoma multiforme molecular characterization Probiotic interventions for gut-liver-muscle axis disorders Nanovesicle-based therapeutics from citrus and tomatoes Diagnostic applications of heat shock proteins in inflammatory diseases Publication analysis reveals consistent focus on chaperone systems across cancer types (thyroid, salivary, colorectal, brain), with recent expansion into nutraceutical mechanisms involving citrus nanovesicles and golden tomatoes. Her 2023-2025 output shows increasing emphasis on multi-organ communication pathways (gut-brain, gut-liver-muscle) and industrial-scale therapeutic applications. Methodologically, she integrates immunohistochemistry, proteomics, and animal disease models. Teaching responsibilities include core anatomy courses for Medicine and Radiology programs: Anatomy I (10 CFU) and II (6 CFU) for Medicine Human Anatomy with Histology elements (6 CFU) for Radiology Integrated Anatomy/Biochemistry/Physiology modules (12 CFU) She actively supervises graduate research, with four theses directed between 2020-2024 covering celiac disease histopathology, stress protein interactions in colorectal cancer, glioblastoma biomarkers, and thyroid stress responses. Her laboratory work focuses on immunomorphological analysis of chaperone systems in tumor tissues and development of probiotic/nanovesicle interventions for metabolic and inflammatory conditions.

Ant Shepherdمشاهده پروفایل

دانشیار

• Clinical Exercise Physiology
• Metabolic Health
• Cardiovascular Function
• +۵ مورد دیگر

Dr. Ant Shepherd is an Associate Professor in Clinical Exercise Physiology at the University of Portsmouth, affiliated with the School of Psychology, Sport and Health Sciences within the Faculty of Science & Health. He also contributes to the Institute of Life Sciences and Healthcare and the Centre for Integrated Health and Wellbeing. Dr. Shepherd holds an ORCID identifier (0000-0001-6392-7944) and is actively involved in PhD supervision and academic leadership. Education: BSc (Hons) Sports Science (Bangor University), MSc Exercise Rehabilitation (Bangor University), PhD (University of Exeter, 2015) Postdoctoral Experience: University of Exeter Medical School Research Interests: Dr. Shepherd focuses on using novel interventions—such as nutritional strategies and exposure to extreme environments—to improve metabolic and cardiovascular health. His work emphasizes patient-centered outcomes, particularly in chronic conditions like type 2 diabetes, cystic fibrosis, and chronic obstructive pulmonary disease. He explores disease pathophysiology to identify therapeutic strategies. Publications: His recent work includes studies on cardiovascular function in cystic fibrosis patients, the effects of ketone esters in diabetes, and the role of nitrate in vascular health. Articles often employ randomized controlled trials and observational designs. Awards: Runner-up, Inaugural Annual Review Prize of the Physiological Society (2021) Advising & Grants: Supervises multiple PhD students and postdocs. Serves as a grant reviewer for the Medical Research Council and reviews for journals including Journal of Applied Physiology and Thorax . Active in collaborative projects, such as investigating climate adaptation strategies in diabetes and the effects of passive heating on older adults. Labs & Teams: Leads research teams in translational exercise physiology and collaborates internationally on projects related to cystic fibrosis, diabetes, and vascular health.

Jaap Keijerمشاهده پروفایل

استاد

• Energy metabolism
• Mitochondrial function
• Metabolic pathways
• +۷ مورد دیگر

Jaap Keijer is a Full Professor and Chairholder in the Department of Human and Animal Physiology at Wageningen University & Research. His research focuses on metabolic physiology, particularly energy metabolism, mitochondrial function, and the interplay between diet, aging, and chronic metabolic diseases. He leads projects investigating nicotinamide nucleotide transhydrogenase (NNT) in energy metabolism, galactose's effects on metabolic programming, and the role of environmental factors like hypoxia in muscle physiology. He serves on the editorial board of Molecular Nutrition and Food Research and advises the German Institute of Human Nutrition. His work integrates molecular, cellular, and whole-organism approaches to understand health and disease mechanisms. Key research themes include metabolic adaptations in obesity, mitochondrial dysfunction in aging, and translational biomarker development for physical activity and metabolic health. Dr. Keijer teaches courses on molecular nutritional physiology, model organisms for lifespan research, and dissection-free human/animal physiology. His projects address clinical challenges such as sarcopenia, atrial fibrillation, and nutrient interventions for metabolic disorders. Recent studies explore dietary galactose's programming effects on intestinal metabolism and the impact of NNT deficiency on cardiac health. His lab employs advanced techniques like single-cell transcriptomics and Seahorse extracellular flux analysis to study metabolic pathways in humans and animal models. Publications emphasize mitochondrial dysfunction, metabolic biomarkers, and translational models for aging and disease. His work bridges basic research and clinical applications, aiming to improve metabolic health through dietary and lifestyle interventions. Current initiatives include developing a human gut-on-a-chip model and validating integrative biomarkers for physical activity in adolescents.