جست‌وجوی استاد و پژوهشگر

Ajith Karunarathneمشاهده پروفایل

دانشیار

• Biological Chemistry
• Chemical Biology
• Molecular Pharmacology
• +۴ مورد دیگر

Ajith Karunarathne, Ph.D., is an Associate Professor of Chemistry at Saint Louis University, affiliated with the School of Science and Engineering. His research focuses on Biological Chemistry, Chemical Biology, and Molecular Pharmacology, with a particular emphasis on optogenetic tools and G protein signaling. He earned his Ph.D. in Biological Chemistry from Michigan State University and completed postdoctoral training in Signal Transduction and Optogenetics at Washington University School of Medicine. Education: Ph.D. in Biological Chemistry, Michigan State University Postdoctoral Training in Signal Transduction and Optogenetics, Washington University School of Medicine His research group investigates subcellular signaling mechanisms, optogenetic tool development, and the interplay between light, retinal, and cellular toxicity. Key projects include engineering opsins for in vivo applications, studying G protein signaling pathways, and exploring phytopharmacology for targeted drug delivery. His work bridges molecular biology with pharmacology, aiming to uncover disease mechanisms and develop therapeutic strategies. Publications highlight his contributions to understanding G protein dynamics, optogenetic methodologies, and light-induced toxicity. While no formal awards are listed, his extensive publication record reflects his scholarly impact. Advising and grants are not explicitly detailed, but his research involves collaboration with institutions like Washington University and SLU labs. His lab focuses on interdisciplinary approaches to signaling and pharmacological innovation.

Christoph Fahlkeمشاهده پروفایل

استاد

• Membrane Physiology
• Neuroscience
• Biophysics
• +۳ مورد دیگر

Prof. Christoph Fahlke is a Professor at the Institute for Biological Information Processes (IBI) within Forschungszentrum Jülich, leading the Molecular and Cellular Physiology (IBI-1) department. His research focuses on membrane transport mechanisms, synaptic transmission, and the pathophysiology of genetic disorders. Recent work emphasizes the role of glutamate transporters and CLC anion channels in neurological diseases. Key research areas include: Mechanisms of ion transport in excitable cells Structure-function relationships of transporters like EAAT and ClC proteins Genetic mutations linked to neurodevelopmental disorders CLC channel modulation by fluoride and metabolic signals His publications highlight collaborative approaches combining experimental and computational methods to study ion channels. Notable contributions include elucidating CLC-3's role in pain perception and EAAT-linked ataxias. Current work explores how transporter dysfunction impacts glial and neuronal physiology. Prof. Fahlke's lab is part of the Helmholtz Association and collaborates widely, contributing to projects like the Peter Grünberg Institut. He has authored over 50 peer-reviewed articles and holds an ORCID ID: 0000-0001-8602-9952.

• Retinal Imaging
• Optical Coherence Tomography Angiography (OCTA)
• Glaucoma Research
• +۳ مورد دیگر

Corey A. Smith is a Professor in the Department of Ophthalmology & Visual Sciences at Dalhousie University's Faculty of Medicine, focused on retinal imaging and optical coherence tomography angiography (OCTA) . His research balances experimental methods with clinical relevance , emphasizing 3D image analysis and artificial intelligence applications in understanding retinal diseases like glaucoma. Research priorities : interdisciplinary collaboration, OCTA optimization, clinical data integration Students : Masters and Honours students in biomedical engineering and medical sciences Recent publications highlight his work in macular perfusion density , ganglion cell asymmetry , and transsynaptic vascular changes . Awards and educational background are not explicitly mentioned in the provided texts, though opportunities for trainees are advertised.

Sandra Gemmaمشاهده پروفایل

دانشیار

• Medicinal Chemistry
• Antiviral Drug Development
• Antiparasitic Agents
• +۳ مورد دیگر

Sandra Gemma is an Associate Professor at the University of Siena's Department of Biotechnology, Chemistry and Pharmacy. Her research focuses on medicinal chemistry approaches for developing therapeutics against infectious diseases, cancer, and fibrotic conditions. She specializes in structure-based drug design targeting viral proteases (including SARS-CoV-2 and monkeypox), parasitic enzymes (trypanothione reductase in Leishmania), and bacterial quorum sensing mechanisms in ESKAPE pathogens. Her research integrates: Design and synthesis of enzyme inhibitors (HDACs, proteases, reductases) Development of epigenetic modulators for oncology and retinal diseases Exploration of natural products for wound healing and anti-infective applications Medicinal chemistry optimization of heterocyclic scaffolds (quinolones, quinazolines, spiroindolines) Publication analysis reveals strong focus on: Targeted protein degradation (PROTACs) and covalent inhibitors Multi-target epigenetic modulators for fibrosis and leukemia Structure-guided optimization of antiviral and antiparasitic compounds Translational applications of natural product derivatives She advises pharmacy students on experimental theses covering antiviral synthesis, anti-leishmanial agents, and quorum sensing disruptors. No funded grants or awards were documented in available materials.

Gerardo R. Vastaمشاهده پروفایل

استاد

• Glycobiology
• Glycoimmunology
• Lectin research
• +۷ مورد دیگر

Gerardo R. Vasta, PhD is a Professor in the Department of Microbiology and Immunology at the University of Maryland School of Medicine and the Institute of Marine and Environmental Technology. With a distinguished academic career spanning over four decades, Dr. Vasta has established himself as a leading research scientist in glycosciences, particularly in the field of protein-carbohydrate interactions in innate immunity, development, and cancer. Dr. Vasta's research program has been continuously supported by major funding agencies including the National Science Foundation, National Institutes of Health, and National Oceanic and Atmospheric Administration. His work has revealed key insights into the structural and functional relationships of carbohydrate binding proteins across diverse model systems including zebrafish, C. elegans, eastern oyster, and mice. Early in his career, he focused on C-type lectins in innate immune recognition in non-mammalian models, which later evolved into extensive studies on galectins in development, immune regulation, and pathogen recognition. His laboratory has made significant contributions to understanding galectin roles in skeletal muscle development, eye lens development, retinal regeneration, prostate cancer diagnostics, and host-pathogen interactions. Notably, his research demonstrated that galectins can recognize pathogenic viruses such as influenza A and facilitate viral infection while promoting subsequent pneumococcal pneumonia. His work spans fundamental structural and biophysical aspects of protein-carbohydrate interactions to translational applications including the development of natural and synthetic inhibitors for lectin binding. Dr. Vasta's scientific contributions are reflected in numerous high-impact publications, including a seminal 2009 review in Nature Reviews Microbiology titled 'Roles of galectins in infection.' His research shows a consistent evolution from basic characterization of lectins in invertebrate systems to sophisticated molecular understanding of galectin functions across species, with implications for human health and disease. J. William Fulbright Scholar International Award (2007) National Award 'Raíces' from Argentina's Department of Science, Technology, and Innovation (2016) Faculty Award from University of Maryland Biotechnology Institute (2006) Board of Scientific Counselors Review at National Institute of Dental and Craniofacial Research (2011) Editorial Board Member for Glycobiology, Journal of Marine Biology, and Invertebrate Immunity Throughout his career, Dr. Vasta has been deeply committed to education and training, mentoring numerous PhD and MSc students while regularly hosting high school and undergraduate summer interns in his laboratory. His research has involved extensive collaborations across disciplines, demonstrating his ability to bridge fundamental glycobiology with practical applications in immunology, infectious disease, and cancer research.

• Glaucoma
• Age-related Macular Degeneration
• Ophthalmology
• +۴ مورد دیگر

Dr. Jonathan Denniss is an Associate Professor at the School of Optometry & Vision Science, part of the Faculty of Life Sciences at the University of Bradford. He earned his MSc in Optometry from the University of Manchester (2007) and a PhD in Glaucoma Structure-Function Relationships (2010). His career includes postdoctoral roles at the University of Melbourne (Australia) and the University of Nottingham’s Visual Neuroscience Group. His research focuses on age-related eye diseases like glaucoma and macular degeneration, employing imaging, computer simulations, and psychophysical techniques. Key projects include improving glaucoma detection via en face OCT analysis and customizing perimetric tests for individual patients. He leads the College of Optometrists-accredited Professional Higher Certificate in Glaucoma and oversees postgraduate research in his department. Research interests span clinical diagnostics, ocular imaging innovations, and translating findings into automotive industry applications. He actively mentors prospective PhD students exploring age-related vision disorders. Publications emphasize structure-function correlations in glaucoma, OCT advancements, and patient-centric visual testing improvements. His work bridges clinical practice and technological innovation in ophthalmology.

• Cell Biology
• Biochemistry
• Electron Microscopy techniques
• +۴ مورد دیگر

Pedro Fale is a Research Fellow at the Institute of Ophthalmology , University College London. His research focuses on Cell Biology , Biochemistry , and Electron Microscopy techniques , with an emphasis on molecular imaging and subcellular analysis. Education: Not explicitly detailed in the text. His work spans cellular physiology, nutraceutical potential of natural products, and advanced spectroscopic methodologies. Recent publications highlight investigations into lysosomal dynamics in retinal pigment epithelial cells, phytochemical profiling of seaweed and microalgae, and the use of synchrotron-based imaging for subcellular resolution. Key collaborations include researchers at institutions such as the University of Lisbon, where he served as a Guest Assistant Professor from 2016-2019, teaching Experimental Biochemistry and advising multiple MSc and PhD students.

• Molecular Modeling
• Drug Design
• Biomaterials
• +۳ مورد دیگر

Juan Jesus Perez Gonzalez is a Professor at the Universitat Politècnica de Catalunya (UPC), affiliated with the Department of Chemical Engineering and the Barcelona School of Industrial Engineering (ETSEIB). He leads the GBMI research group (Grup de Biotecnologia Molecular i Industrial) and is part of the CEBIM (Centre de Biotecnologia Molecular). His work focuses on computational chemistry, molecular modeling, drug design, and biomaterials, with over 348 documented activities including articles, projects, and presentations. Research interests span structural biochemistry, protein-ligand interactions, and the application of computational methods to drug discovery. Notable contributions include studies on SARS-CoV-2 inhibitors, K-RAS allosteric sites, and rhodopsin mutations linked to retinitis pigmentosa. He has collaborated on projects funded by national and international grants, emphasizing sustainability and interdisciplinary research. Over 197 indexed articles and 77 conference presentations highlight his prolific output. Key projects include 'Raise excellence in R&S&I in HEI for widening countries' and contributions to the 'Unite! University Network for Innovation, Technology and Engineering.' His research also explores green transitions and sustainable science through workshops and collaborative initiatives. Perez Gonzalez holds ORCID (0000-0002-0748-8147) and ResearcherID (E-3710-2010), reflecting his international academic engagement. His lab and team activities emphasize computational tools for drug design and biomaterials innovation.

Abigail Fahimمشاهده پروفایل

استادیار

• Inherited Retinal Diseases
• Ocular Genetics
• Retinal Imaging
• +۷ مورد دیگر

Abigail Fahim is an Assistant Professor in the Department of Ophthalmology and Visual Sciences at the University of Michigan Medical School. She is actively affiliated with the UM Kellogg Eye Center and contributes to the Foundation Fighting Blindness Clinical Consortium, a collaboration of 41 international clinical centers managing patients with inherited retinal diseases (IRDs). Dr. Fahim's research focuses on inherited retinal diseases with particular emphasis on genetic testing disparities across racial groups, choroideremia, Stargardt disease, and USH2A-related retinal degeneration. Her work spans both clinical and basic science domains, investigating genetic detection rates, retinal structure-function relationships, and molecular mechanisms underlying retinal degeneration. She has made significant contributions to understanding why Black patients with IRDs have lower genetic detection rates compared to non-Hispanic White patients. Analysis of Dr. Fahim's recent publications reveals a strong focus on translational research bridging genetic discoveries with clinical applications. Her work demonstrates expertise in retinal imaging, genetic testing interpretation, and disease progression monitoring. The research spans multiple continents through the Foundation Fighting Blindness Consortium, highlighting her international collaborative approach to tackling inherited retinal diseases. Dr. Fahim serves on editorial teams for prominent ophthalmology journals including Investigative Ophthalmology & Visual Science, where she co-authored an editorial on supporting effective peer review. Her research is supported through multiple University of Michigan grants and collaborations with the Foundation Fighting Blindness. She is actively involved with the UM Kellogg Eye Center research team and collaborates extensively with colleagues including Kari Branham, Kanishka Jayasundera, and other members of the Foundation Fighting Blindness Clinical Consortium. Her work combines clinical research with laboratory investigations to advance understanding and treatment of inherited retinal diseases.

• Neuro-Ophthalmology
• Retinal Diseases
• Optic Nerve Disorders
• +۳ مورد دیگر

Steffen Hamann serves as Clinical Professor in the Department of Ophthalmology within the Faculty of Health and Medical Sciences at the University of Copenhagen. His clinical and research activities are centered at Rigshospitalet (Copenhagen University Hospital) with office address at Blegdamsvej 3, 2200 København N. His work bridges clinical ophthalmology with neuro-ophthalmic research, focusing on diagnostic and therapeutic challenges in optic nerve disorders. Professor Hamann's primary research interests include neuro-ophthalmology with special emphasis on optic disc drusen, retinal vascular diseases, and AI applications in ophthalmic diagnostics. His laboratory investigates anatomical correlates of optic nerve pathologies, inflammatory markers in vasculitic eye diseases, and time-sensitive interventions for acute vision loss conditions. Current projects involve multicenter clinical trials for retinal artery occlusion and genetic studies of familial optic disc drusen. Analysis of his recent publications reveals strong concentration in three interconnected domains: (1) Optic disc drusen pathophysiology and management strategies, (2) AI-enhanced diagnostic approaches for acute retinal vascular events, and (3) Systemic disease manifestations in neuro-ophthalmology. His collaborative network spans European stroke specialists, AI researchers, and international ophthalmology centers. Principal Investigator for TenCRAOS (Tenecteplase in Central Retinal Artery Occlusion Study) Lead researcher in Nordic collaborative projects on optic disc drusen epidemiology Active participant in European networks for neuro-ophthalmic emergency protocols Professor Hamann maintains strong clinical ties with Rigshospitalet's Department of Ophthalmology while directing translational research that bridges bench findings with bedside applications. His work increasingly incorporates artificial intelligence for early detection of time-critical ophthalmic conditions.

Colenso Speerمشاهده پروفایل

دانشیار

• Neural Circuit Development
• Visual System Maturation
• Synaptic Connectivity
• +۱ مورد دیگر

Colenso Speer is an Associate Professor in the Department of Biology at the University of Maryland. His research examines molecular-genetic programs and activity patterns that drive neural circuit maturation in the mammalian visual system. The Speer Lab investigates structure/function relationships in visual microcircuits using genetic labeling, electrophysiology, and advanced imaging techniques. Recent work focuses on synaptic clustering mechanisms underlying eye-specific competition and proteomic transitions during circadian pacemaker development. Key methodologies include volumetric super-resolution imaging (STORM), 3D-STORM tissue imaging, and computational analysis of neural architecture. Research aims to advance understanding of neurodevelopmental disorders and therapeutic approaches.

Kevin Drewمشاهده پروفایل

استادیار

• Molecular Interactions
• Proteomics
• Computational Biology
• +۴ مورد دیگر

Kevin Drew is an Assistant Professor in the Department of Biological Sciences at the University of Illinois Chicago's College of Liberal Arts and Sciences. His research focuses on developing computational and biochemical tools to systematically characterize molecular interactions in cells, with applications in understanding disease mechanisms and therapeutic development. Education includes a Ph.D. in Biology – Molecular Biophysics from New York University School of Medicine (2014), M.S. in Computer Science from University of Chicago (2005), and B.S. in Computer Science from University of Iowa (2003). Research interests span molecular interactions, proteomics, computational biology, structural biology, machine learning applications in biology, macromolecular assemblies, and drug design. The Drew Lab employs biochemical, computational, and proteomic approaches to identify cellular macromolecular assemblies, characterize their structural states, determine 3D structures, and develop interaction modulators. Publications demonstrate consistent focus on proteomics, computational modeling of protein complexes, and biomolecular interaction analysis. Recent work emphasizes high-throughput methods for complex identification, evolutionary conservation of interactions, and therapeutic targeting of protein interfaces. No awards or student advising information was available. Lab activities at the Drew Lab include systematic characterization of macromolecular assemblies using interdisciplinary approaches.

King-Wai Yauمشاهده پروفایل

استاد

• Cellular Neuroscience
• Molecular Neuroscience
• Sensory Transduction
• +۴ مورد دیگر

King-Wai Yau is a Professor of Neuroscience at the Solomon H. Snyder Department of Neuroscience, Johns Hopkins University School of Medicine. His research focuses on sensory transduction processes in vision and olfaction, particularly phototransduction in rods, cones, and intrinsically photosensitive retinal ganglion cells (ipRGCs), as well as olfactory transduction mechanisms. Yau’s work explores how light and odorant signals are converted into electrical signals, with emphasis on cyclic nucleotide pathways, calcium feedback mechanisms, and signal amplification. He investigates topics such as light adaptation, melanopsin signaling, and the structural-functional relationships of photoreceptors in mammals and teleosts. Yau’s lab has pioneered studies on ipRGCs, revealing their dual roles in conveying rod/cone signals and intrinsic light detection. Key discoveries include the role of melanopsin in non-image-forming vision (e.g., circadian rhythms, pupillary reflex), the molecular basis of phototransduction in these cells, and comparisons with traditional rod/cone pathways. His work also addresses olfactory receptor neuron transduction, including odorant-receptor specificity and cAMP-mediated signaling. Yau has advised multiple graduate students and postdoctoral fellows, including Yaqing YE, Zuying CHAI, and others. His lab integrates electrophysiology, molecular genetics, and imaging techniques to study retinal physiology and sensory biology. Current projects include understanding phototransduction kinetics, light-induced signaling cascades, and the evolutionary adaptations of sensory systems. His research has been published in top-tier journals such as Nature , Science , and Neuron , with over 15 highlighted publications since 2002. Yau serves on the faculty of the Neuroscience Training Program and Biochemistry, Cellular and Molecular Biology Graduate Program.

Vardan T. Karamyanمشاهده پروفایل

استاد

• Neurodegenerative Disorders
• Cardiovascular Disorders
• Enzyme and Receptor Pharmacology
• +۱۳ مورد دیگر

Vardan T. Karamyan is a Professor in the Department of Foundational Medical Studies at the Oakland University William Beaumont School of Medicine (OUWB), where he also heads the Laboratory for Neurodegenerative Disease and Drug Discovery. He joined OUWB in September 2022, after a distinguished career at Texas Tech University Health Sciences Center, where he served as Full Professor and Vice-Chair of Pharmaceutical Sciences. Pharm.D., Faculty of Pharmacy, Yerevan State Medical University Ph.D., Biology, Institute of Biochemistry, National Academy of Sciences of Armenia Postdoctoral Training, Pharmacology, University of Mississippi Dr. Karamyan’s research spans enzyme and receptor pharmacology, chemical biology, and drug discovery, with a focus on neurodegenerative and cardiovascular disorders. His work integrates molecular, biochemical, and behavioral approaches to study ischemic stroke, Alzheimer’s disease, and vascular dementia. Key areas include the role of neuropeptides like neurolysin (Nln) in modulating the blood-brain barrier, allosteric activation of peptidases (e.g., ACE2, neprilysin), and mechanisms of neuroplasticity and functional recovery after stroke. His recent publications reflect a strong trend toward translational neuroscience, with an emphasis on developing novel therapeutics and refining preclinical models. Articles highlight small molecule activators of neurolysin, challenges in ACE2 pharmacology, and innovative low-cost stroke models, underscoring a commitment to both mechanistic insight and practical application. Dr. Karamyan has received research funding from the National Institutes of Health (NIH) and the American Heart Association (AHA) , recognizing the significance and impact of his work. As an educator, he has been consistently recognized by students and peers for excellence in teaching pharmacy and graduate students. He mentors PhD students and postdoctoral fellows, fostering an inclusive environment that promotes academic success and innovation. His laboratory actively investigates neurolysin biology, peptidase modulation, and stroke recovery mechanisms, contributing to a deeper understanding of neurodegenerative diseases and advancing therapeutic strategies.

Shannon Barwickمشاهده پروفایل

استادیار

• Anatomy
• Cell Biology
• Ophthalmology
• +۳ مورد دیگر

Shannon Barwick serves as an Assistant Professor at Augusta University's Medical College of Georgia with dual appointments in the Department of Cellular Biology and Anatomy and the Department of Obstetrics and Gynecology. She teaches foundational medical courses including Human Gross Anatomy (CAHS 7400), Cardiopulmonary/Heme (MEDI 6220), and Integrative Science (MEDI 5005), and holds active roles in curriculum development and student mentoring. Education: Ph.D. in Cell/Cellular Biology and Anatomy, Augusta University (2022) B.S. in Biochemistry, Converse College (2017) Anatomy Training Program Certificates (Neuroanatomy, Trunk, Head/Neck, Limbs), AAA and Anatomical Society (2023-2024) Certificate in Inclusive Excellence Program, Office of Diversity and Inclusion Future Faculty Learning Community Certificate (2023) Research Focus: Dr. Barwick's work centers on retinal structure-function relationships, investigating metabolic disorders like hyperhomocysteinemia in mouse models and molecular mechanisms involving Sigma 1 Receptor/NRF2 pathways in photoreceptor cells. Her medical education research emphasizes inclusive teaching practices and anatomy curriculum innovation, supported by her Certificate in Inclusive Excellence and active participation in faculty development programs. Scholarly Trends: Her publications reveal a concentrated focus on retinal pathophysiology using transgenic models, with strong connections between metabolic biochemistry and visual neuroscience. The work bridges cellular biology with clinical ophthalmology, particularly examining oxidative stress pathways in degenerative eye conditions through molecular localization studies and functional assessments. Honors: AY2023/24 Exemplary Teaching Award, MCG Office of Academic Affairs Mentoring & Service: As Faculty Mentor and OBGYN Anatomy Clinical Readiness Elective Co-Course Director, she guides medical students while serving on critical committees including the Pre-Clerkship Committee, 3MT Planning Committee, and MCG Admission Interview panel. Her departmental service includes chairing the CBA Anatomy Chair Search and participating in the Vision Discovery Institute. Research Affiliation: Dr. Barwick coordinates data sessions for the Vision Discovery Institute Retreat, connecting her retinal research with Augusta University's broader vision science initiatives through this interdisciplinary research consortium.